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 TERMINÉ 

BIOlogical therapy CYCLEs towards tailored, needs-driven, safer and cost-effective management of Crohn’s disease (BIOCYCLE)

Date du début: 1 avr. 2015, Date de fin: 31 mars 2021,

"The BIOCYCLE Project proposes to test and critically assess the benefits and risks of an innovative regimen for improving the treatment of Crohn’s disease (CD), a chronic immune-mediated inflammatory disease affecting the gastro-intestinal tract of an increasing number of patients. Currently, the combination of anti-TNFα monoclonal antibodies and immunosuppressants used without interruption is th ...
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 13

 TERMINÉ 

Innovative Network for Monte Carlo Event Generators for LHC Physics (MCnetITN3)

Date du début: 1 avr. 2017, Date de fin: 31 mars 2021,

We propose a European Training Network that will provide a total of 540 ESR-months of training in Monte Carlo event generator physics and techniques, and related applications in experimental particle physics.Monte Carlo event generators are central to high energy particle physics. They are used by almost all experimental collaborations to plan their experiments and analyze their data, and by theo ...
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 9

 TERMINÉ 

Directed Protein Evolution for Synthetic Biology and Biocatalysis (ES-Cat)

Date du début: 1 mars 2017, Date de fin: 28 févr. 2021,

ES-Cat will use directed evolution as a tool to reproduce Nature's remarkable ability to generate molecular machines - in particular enzymes – that perform at levels near perfection. Instead of seeing rational and combinatorial approaches as alternatives, we combine them in this network to achieve a ‘smarter’ and more efficient exploration of protein sequence space. By harnessing the forces of Dar ...
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 11

 TERMINÉ 

MetaMaterials antenna for ultra-high field MRI (M-CUBE)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

M-Cube aims at changing the paradigm of High-Field MRI and Ultra High-Field antennas to offer a much better insight on the human body and enable earlier detection of diseases. Our main objective is to go beyond the limits of MRI clinical imaging and radically improve spatial and temporal resolutions. The clinical use of High-field MRI scanners is drastically limited due to the lack of homogeneity ...
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 13

 TERMINÉ 

TRANSlating the role of Mitochondria in Tumorigenesis (TRANSMIT)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The consolidation of the knowledge that cancer is not only a genetic, but also a metabolic disease, has led scientists to investigate the intricate metabolic plasticity that transformed cells must undergo to survive the adverse tumor microenvironment conditions, and the contribution of oncogenes and tumor suppressors in shaping metabolism. In this scenario, genetic, biochemical and clinical eviden ...
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 10

 TERMINÉ 

Preparation for EMPHASIS: European Infrastructure for multi-scale Plant Phenomics and Simulation for food security in a changing climate (EMPHASIS-PREP)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Sustainable food security and increasing availability of plant biomass for human nutrition and bioindustries is the key challenge for the coming decades. The analysis of crop performance with respect to structure, function, quality and interaction with the environment (“phenotyping”) remains the bottleneck for the exploitation of crop genetic diversity required for the enhancement of plant product ...
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 9

 TERMINÉ 

Expectations and Social Influence Dynamics in Economics (ExSIDE)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Expectations play a crucial role in determining the behaviour of many economic decision makers. The recent financial and economic crisis has highlighted the importance of expectation dynamics for economic development, the success of firm strategies and public policies. The Innovative Training Network ExSIDE aims at improving our understanding of the role of expectation formation and social influen ...
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 7

 TERMINÉ 

An integrated mulTidisciplinary appRoach towards a new generAtIon of aNtibiotics: Targeting function and cross-talk of bacterial Envelope proTein machineries (Train2Target)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Train2Target is a multidisciplinary European Training Network built to address the challenge of the discovery of alternative antimicrobials. Innovative strategies to deliver a next generation of drugs are urgently needed. The alarming threats and spread of multi-drug resistant bacteria is currently leaving clinicians with very limited options to combat infections especially those from Gram-negativ ...
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 11

 TERMINÉ 

Advanced Prediction in Polar regions and beyond: Modelling, observing system design and LInkages associated with ArctiC ClimATE change (APPLICATE)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,

Arctic climate change increases the need of a growing number of stakeholders for trustworthy weather and climate predictions, both within the Arctic and beyond. APPLICATE will address this challenge and develop enhanced predictive capacity by bringing together scientists from academia, research institutions and operational prediction centres, including experts in weather and climate prediction and ...
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 16

 TERMINÉ 

OPtimising thERapy to prevent Avoidable hospital admissions in the Multimorbid elderly (OPERAM)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,

Most older adults have multiple chronic diseases (multimorbidity) and multiple medications (polypharmacy). However, multimorbid patients are often excluded from clinical trials and most guidelines address diseases in isolation. Inappropriate drug prescription and poor drug compliance are common and contribute to up to 30% of hospital admissions. OPERAM investigators developed STOPP/START criteria ...
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 9

 TERMINÉ 

BRIdges the GAp for Innovations in Disaster resilience (BRIGAID)

Date du début: 1 mai 2016, Date de fin: 30 avr. 2020,

Recent studies from the IPCC indicate that Europe is particularly prone to increased risks of river and coastal floods, droughts resulting in water restrictions and damages from extreme weather such as heat events and wildfires. Evaluations also show a huge potential to reduce these risks with novel adaptation strategies. Researchers, innovators and incubators develop innovative products and servi ...
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 24

 TERMINÉ 

A multi-center randomized, placebo-controlled trial of mirabegron, a new beta3-adrenergic receptor agonist on left ventricular mass and diastolic function in patients with structural heart disease (BETA3_LVH)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,

Patients with cardiovascular risk factors, e.g. hypertension and obesity are at risk of developing heart failure with preserved ejection fraction (HFpEF), a highly prevalent disease in the elderly, mostly women population. There is currently no specific, defined treatment for HFpEF, beyond control of risk factors. Activation of cardiac and vascular Beta3-adrenergic receptors (B3AR) represents a ne ...
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 15

 TERMINÉ 

Robust and Efficient Approaches to Evaluating Side Channel and Fault Attack Resilience (REASSURE)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,

...urers (NXP, MORPHO), a highly respected side channel testing lab (Riscure), an engaged governmental representative (ANSSI), and two of the most prominent research institutions in this field (UCL, University of Bristol).
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 6

 TERMINÉ 

Advanced Networking for Nuclear Education and Training and Transfer of Expertise (ANNETTE)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

The present situation of nuclear energy in Europe asks for a continuing effort in the field of Education and Training aimed to assure a qualified workforce in the next decades. In this scenario, the present proposal is aimed at enhancing and networking the Europe-wide efforts initiated in the past decades by different organisations belonging to academia, research centres and industry to maintain a ...
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 25

 TERMINÉ 

PRocess-based climate sIMulation: AdVances in high resolution modelling and European climate Risk Assessment (PRIMAVERA)

Date du début: 1 nov. 2015, Date de fin: 31 oct. 2019,

The goal of PRIMAVERA is to deliver novel, advanced and well-evaluated high-resolution global climate models (GCMs), capable of simulating and predicting regional climate with unprecedented fidelity, out to 2050. This capability will deliver innovative climate science and a new generation of advanced Earth System Models. Sector-specific end-users in policy and business will be identified and engag ...
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 19

 TERMINÉ 

Advanced Multi-Variate Analysis for New Physics Searches at the LHC (AMVA4NewPhysics)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

With the 2012 discovery of the Higgs boson at the Large Hadron Collider, LHC, the Standard Model of particle physics has been completed, emerging as a most successful description of matter at the smallest distance scales. But as is always the case, the observation of this particle has also heralded the dawn of a new era in the field: particle physics is now turning to the mysteries posed by the pr ...
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 9

 TERMINÉ 

BIOactive implantable CApsule for PANcreatic islets immunosuppression free therapy (BIOCAPAN)

Date du début: 1 juin 2015, Date de fin: 31 mai 2019,

The key therapeutic issue in diabetes mellitus type I and II is glycaemic control. Reductions of constant self-control, of insulin injections, and of long-term complications would have tremendous benefit for quality of life. The best therapy option is the transplantation of allogeneic islet cells, but the current state of the art limits the applicability of this approach. Implanting unprotected gr ...
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 10

 TERMINÉ 

Advanced European Infrastructures for Detectors at Accelerators (AIDA-2020)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,

Particle physics is at the forefront of the ERA, attracting a global community of more than 10,000 scientists. With the upgrade of the LHC and the preparation of new experiments, the community will have to overcome unprecedented challenges in order to answer fundamental questions concerning the Higgs boson, neutrinos, and physics beyond the Standard Model. Major developments in detector technology ...
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 38

 TERMINÉ 

Rebuilding an Inclusive, Value-based Europe of Solidarity and Trust through Social Investments (RE-InVEST)

Date du début: 1 mars 2015, Date de fin: 28 févr. 2019,

In 2013, as a response to rising inequalities, poverty and distrust in the EU, the Commission launched a major endeavour to rebalance economic and social policies with the Social Investment Package (SIP). RE-InVEST aims to strengthen the philosophical, institutional and empirical underpinnings of the SIP, based on social investment in human rights and capabilities. Our consortium is embedded in th ...
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 19

 TERMINÉ 

Radiation Innovations for Therapy and Education (RADIATE)

Date du début: 1 mars 2015, Date de fin: 28 févr. 2019,

Approximately 45-60% of all cancer patients are treated with radiotherapy. Some of these patients have a good outcome, but in other cases their illness fails to be cured. This may result from distant metastases or from regrowth of the primary tumor. This training network is built on the premise that considerable advances in understanding radiobiology will open novel routes for effective therapeuti ...
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 6

 TERMINÉ 

Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases (PRECISESADS)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

We concur to the IMI on “Reclassification of SLE, connective tissue diseases and RA” call by presenting a proposal aimed at using the power of OMICs, and bioinformatics to identify new classifications for diseases known to share common pathophysiological mechanisms. Such knowledge has not been applied to individual patients, depriving them from potential benefits in terms of the use of new therape ...
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 30

 TERMINÉ 

Integrating Cultural Diversity in Higher Education

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2018,

HE4u2 will contribute to the reform of teaching and learning in higher education and the improvement of the retention and attainment of migrants and ethnic minority students.There is a clear need and demand for training of teachers in relation to migrant students, for reform in the delivery of support for these learners, and in the intercultural dimension for all learners. HE4u2 will develop an in ...
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 8

 TERMINÉ 

Microbiome Influence on Energy balance and Brain Development-Function Put into Action to Tackle Diet-related Diseases and Behavior (MyNewGut)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2018,

Emerging evidence indicates that the gut microbiome contributes to our ability to extract energy from the diet and influences development and function of the immune, endocrine and nervous systems, which regulate energy balance and behaviour. This has led to hypothesize that developing microbiome-based dietary interventions can be cost-effective measures to prevent diet-related and behavioural diso ...
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 30

 TERMINÉ 

Improving digital health literacy in Europe (IC-Health)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2018,

Citizens' digital health literacy is an essential element for successful eHealth deployment. However, citizens often do not have the necessary skills to find, understand and appraise online health information and apply their knowledge to make health decisions. Digitally health literate citizens are empowered to play a more active role in their health self-management, resulting in improved preventi ...
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 14

 TERMINÉ 

Enhancing the effectiveness of programs and strategies to prevent youth smoking: a comparative realist evaluation of 7 European cities (SILNE-R)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2018,

Cigarette smoking is a main risk factor for premature disease, disability and death in Europe, especially in disadvantaged groups. Prevention of youth smoking is crucial to any strategy aimed at reducing this disease burden in the future. Several potentially effective strategies and programs are available to address youth smoking. However, in practice their impact often appears to be limited, espe ...
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 10

 TERMINÉ 

ODYSSEUS-MONNET NETWORK ON IMMIGRATION AND ASYLUM

Date du début: 1 sept. 2015, Date de fin: 31 août 2018,

The main rationale of the project is to forge, throughout the Member States, a European community of researchers and professors in the field of EU immigration and asylum who, despite the existing important cooperation and personal links, do not benefit from a consistent enough framework at EU level. Establishing “the place to be” virtually or physically sometimes per year to meet, exchange and net ...
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 22

 TERMINÉ 

MASTER GEOGRAPHICAL MODELLING CAMPUS+e

Date du début: 1 sept. 2015, Date de fin: 31 août 2018,

The increased complexity of urban and regional systems and the rise of massive digital and open data require that future students master an enlarged portfolio of geographical modelling tools and can relate them with other types of models in order to innovate in research and in planning practice. Likewise, trainers of geographical models and researchers across Europe also need to cross-fertilize th ...
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 9

 TERMINÉ 

Graphene-based disruptive technologies (GrapheneCore1)

Date du début: 1 avr. 2016, Date de fin: 31 mars 2018,

This project is the second in the series of EC-financed parts of the Graphene Flagship. The Graphene Flagship is a 10 year research and innovation endeavour with a total project cost of 1,000,000,000 euros, funded jointly by the European Commission and member states and associated countries. The first part of the Flagship was a 30-month Collaborative Project, Coordination and Support Action (CP-CS ...
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 158

 TERMINÉ 

From Strategy to Action: Supporting the professionalisation of sport organisations through the definition of work-based competencies and the development of fit-for-purpose training for Sport Administrators

Date du début: 1 sept. 2015, Date de fin: 28 févr. 2018,

This European project uses an innovative tool to analyse and address a crucial skills issue in an increasingly important sector. + THE PROJECT MEETS A REAL NEED. The S2A (Strategy to Action) Project is focussed on the sport and active leisure sector and in particular on the skill needs of sports administrators – the people, in paid and voluntary roles in middle management in national and European ...
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 12

 TERMINÉ 

"Comparing policy framework, structure, effectiveness and cost-effectiveness of functional and integrated systems of mental health care" (COFI)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

"Mental disorders affect 38.2% of the EU population. For reducing the associated burden, countries across Europe engage in costly re-organizations of mental health care systems. Reforms focus on one controversial core question: Should systems be functional or integrated? In functional systems, separate staff in different services are in charge of in- and out-patient care (to enhance specialization ...
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 7

 TERMINÉ 

"Therapeutic Beta-Lactam Monitoring for Stratified Treatment of hospital-acquired pneumonia, improved dose-dependent efficacy, decreased treatment duration, and prevention of emergence of resistance" (MON4STRAT)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

"Stratified clinical treatment interventions meeting patient-specific efficacy (pharmacodynamics) while at the same time lowering the risk of emergence of drug resistance (EDR) and minimizing adverse effects are particularly needed in Hospital-acquired and Ventilator-Associated pneumonia [HAP/VAP] where morbidity, mortality and health care costs remain high. β-lactam antibiotics are at the corners ...
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 13

 TERMINÉ 

Si on SiC for the Harsh Environment of Space (SaSHa)

Date du début: 1 févr. 2016, Date de fin: 31 janv. 2018,

The SaSHa (Si on SiC for the Harsh Environment of Space) project will accelerate the development of an entirely new generation of power electronic semiconductor devices benefitting Space and several terrestrial applications. Proof of concept prototypes (up to TRL5) will be developed that incorporate a brand new Si on SiC substrate solution into state-of-the-art power electronic device architecture ...
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 4

 TERMINÉ 

Volcanic ash: field, laboratory and numerical investigations of processes during its lifecycle (VERTIGO)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

Explosive volcanic eruptions are an unavoidable natural hazard: Volcanic ash, the ejected lethal mixture of crystals, lava, glass and older rocks, is the most far-reaching threat. In April 2010, the ash cloud from Eyjafjall volcano in Iceland, a comparatively small event, paralysed large parts of Europe for up to one week in a manner unique in history. The impact was dramatic: several million pass ...
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 10

 TERMINÉ 

Towards a flexible software-defined network ecosystem (ENDEAVOUR)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2017,

The focus of the project is to enable added-value services to be provided thanks to SDN, on top of Internet Exchange Points and other network interconnnection fabrics. The services would relate not only to the flexibility of the interconnection fabric, but most importantly to enable the content and data centre ecosystem that is present at the interconnection fabric to collaborate. The ultimate goa ...
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 6

 TERMINÉ 

Supramolecular assembly of polymeric structures: a novel route to enhance soft materials properties (SUPOLEN)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

"Supramolecular polymeric assemblies represent an emerging, promising class of systems with superior versatility compared to their covalent polymeric counterparts. They offer exciting new opportunities for stimuli-responsive structures exhibiting reversible tunable properties, with applications in foodstuff, coatings , cost-efficient processes or biomedical areas. To explore their potential and de ...
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 11

 TERMINÉ 

Measurement for Europe: Training and Research for Internet Communications Science (METRICS)

Date du début: 1 sept. 2013, Date de fin: 31 août 2017,

"Measurement for Europe: Training and Research for Internet Communications Science (METRICS) METRICS will offer a unique training and research opportunity for 13 ESRs and one ER in a network comprising seven partners and nine associate partners. The METRICS network comprises four strong academic partners (Aalto, UC3M, UCAM, UCL), three vendors (NEC, Ericsson, Narus), four ISPs (BT, TID, IIJ, Elisa ...
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 7

 TERMINÉ 

Sediment transport in fluvial, estuarine and coastal environment (seditrans)

Date du début: 1 sept. 2013, Date de fin: 31 août 2017,

Sediment transport in the fluvial, estuarine and coastal environment causes significant morphological changes and results in the amplification of floods, storm surges and other inundation hazards. This increases considerably the risk of failure of structures, disruption of function of networks (water, energy), destruction of ecosystems and natural resources, as well as property and human loss. The ...
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 10

 TERMINÉ 

Macroencapsulated Porcine Pancreatic Islets to cure Diabetes Mellitus type 1/2 (XENOISLET)

Date du début: 1 sept. 2013, Date de fin: 31 août 2017,

During the last five years, within the EU FP6 Integrated Project XENOME (LSHB-CT-2006-037377), we have convincingly demonstrated in primates that a complete control of induced type 1 diabetes is routinely obtained for 6/8 months after transplantation of subcutaneous alginate macroencapsulated porcine islets xenograft without the use of any immunosuppression. In order to improve the function of pig ...
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 5

 TERMINÉ 

Virtual Prototyping of Tactile Displays (PROTOTOUCH)

Date du début: 1 mai 2013, Date de fin: 30 avr. 2017,

"It is estimated that touch screen module revenues will reach $23.9 billion by 2017. These user interfaces have become one of the most common input devices for digital media, e.g. in mobile phones and computers. Current devices incorporate relatively primitive vibrotactile haptic-feedback. The aim of PROTOTOUCH is to develop tactile displays with high fidelity haptic recognition, so that buttons w ...
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 10

 TERMINÉ 

New Oral Nanomedicines: Transporting Therapeutic Macromolecules across the Intestinal Barrier (TRANS-INT)

Date du début: 1 mai 2012, Date de fin: 30 avr. 2017,

Despite the increasing number of macromolecules with potential impact in the treatment of devastating systemic diseases, these therapies have failed to deliver on their expectations because they cannot be administered in the fashion which is most cost efficient and has the highest patient compliance: the oral route. The availability of an oral form of administration could lead to a great improveme ...
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 20