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 TERMINÉ 

A Systems medicine approach to chronic inflammatory disease (SYSCID)

Date du début: 1 janv. 2017, Date de fin: 31 mars 2022,

"The SYSCID consortium aims to develop a systems medicine approach for disease prediction in CID. We will focus on three major CID indications with distinct characteristics, yet a large overlap of their molecular risk map: inflammatory bowel disease, systemic lupus erythematodes and rheumatoid arthritis. We have joined 15 partners from major cohorts and initiatives in Europe (e.g.IHEC, ICGC, Twins ...
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 16

 TERMINÉ 
"The BIOCYCLE Project proposes to test and critically assess the benefits and risks of an innovative regimen for improving the treatment of Crohn’s disease (CD), a chronic immune-mediated inflammatory disease affecting the gastro-intestinal tract of an increasing number of patients. Currently, the combination of anti-TNFα monoclonal antibodies and immunosuppressants used without interruption is th ...
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 13

 TERMINÉ 
PROTECTED aims to develop expertise and protective capabilities against Endocrine Disruptors (EDs). EDs and their mixtures are a modern day health concern leading to failing ecological systems, poor agricultural production and health effects such as obesity, cancer and infertility. While analytical methods have advanced enormously, focus has been mainly on synthetic chemicals, overlooking emerging ...
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 11

 TERMINÉ 

Optical Infrared Coordination Network for Astronomy (OPTICON)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Europe has become a global leader in optical-near infrared astronomy through excellence in space and ground-based experimental and theoretical research. While the major infrastructures are delivered through major national and multi-national agencies (ESO, ESA) their continuing scientific competitiveness requires a strong community of scientists and technologists distributed across Europe’s nations ...
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 34

 TERMINÉ 
As the number of older people in Europe grows, increasing healthy life years is a priority. Cognitive decline, dementia (e.g. Alzheimer’s disease, AD), sleep disturbances and depression, all related to psychological distress and anxiety, are significant drivers of reduced quality of life in older adults. This project builds on evidence that lifestyle factors and meditation practice have the potent ...
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 12

 TERMINÉ 
The SeaDataNet pan-European infrastructure has been developed by NODCs and major research institutes from 34 countries. Over 100 marine data centres are connected and provide discovery and access to data resources for all European researchers. Moreover, SeaDataNet is a key infrastructure driving several portals of the European Marine Observation and Data network (EMODnet), initiated by EU DG-MARE ...
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 57

 TERMINÉ 

LIFE IN QUARRIES

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2020,

Background A wide range of temporary habitats is generated by the digging of quarries, with some becoming more permanent. In many cases, the ecological value and ecosystem services quarries could generate are neglected. Quarries can act as stepping stones and play a significant role in regulating green infrastructure in landscapes. In highly urbanised lan ...
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 4

 TERMINÉ 

HOLIstic optimisation of SHIP design and operation for life cycle (HOLISHIP)

Date du début: 1 sept. 2016, Date de fin: 31 août 2020,

Most maritime products are typically associated with large investments and are seldom built in large series. Where other modes of transport benefit from the economy of series production, this is not the case for maritime products which are typically designed to refined customer requirements increasingly determined by the need for high efficiency, flexibility and low environmental impact at a compe ...
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 39

 TERMINÉ 
"Agricultural production in Europe has significantly damaged soil and water resources, ecosystem biodiversity, socio-economic well-being and contributed to climate change. Expected further intensification of production to ensure food safety for population growth must be sustainable to minimise future impacts and negative externalities. This ETN addresses these challenges by training 15 early stage ...
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 11

 TERMINÉ 

Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI)

Date du début: 1 oct. 2013, Date de fin: 31 mars 2020,

Traumatic Brain Injury (TBI) is a major cause of death and disability, leading to great personal suffering to victim and relatives, as well as huge direct and indirect costs to society. Strong ethical, medical, social and health economic reasons therefore exist for improving treatment. The CENTER-TBI project will collect a prospective, contemporary, highly granular, observational dataset of 5400 p ...
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 44

 TERMINÉ 

European Gram Negative Antibacterial Engine (ENABLE)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2020,

The intensive use and misuse of antibiotics has resulted in some level of antibiotic resistance in essentially all human bacterial pathogens. There is a growing concern that the loss of therapeutic options will present us with a post-antibiotic era where present and future medical advances are negated. Resistant bacteria dramatically reduce the possibilities of treating infections effectively, a ...
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 42

 TERMINÉ 

ISOTOPIC LABELING FOR DRUG INNOVATION (ISOTOPICS)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

Excessive attrition rates during clinical trials dramatically impact on Drug Discovery and Development (DDD). Absorption, Distribution, Metabolism and Excretion studies carried out on larger series of drug candidates at an earlier stage of the DDD timeline and evaluation of drug efficacy through better assessment of pharmacokinetic/pharmacodynamic relationships, target engagement and receptor occu ...
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 8

 TERMINÉ 
Our proposal encompasses parallel clinical trials addressing the feasibility and the effectiveness of donor-derived regulatory T cells (Treg) as a therapeutic agent in the treatment and prevention of tissue and organ damage resulting from graft versus host disease (GVHD) after hematopoietic stem cell transplantation (HSCT).We propose a collaborative clinical study in which Treg therapy for GHVD is ...
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 8

 TERMINÉ 

People for tHe eurOpean bioENergy mIX (Phoenix)

Date du début: 1 déc. 2015, Date de fin: 30 nov. 2019,

The development and adoption of renewable and sustainable forms of energy has become a major priority for Europe and is an important theme in H2020. Research into new, energy-related technologies to reduce Europe’s reliance on non-renewable fossil fuels is a critical need, and requires more newly qualified people in areas such as renewable-energy infrastructure management, new energy materials and ...
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 15

 TERMINÉ 
What is consciousness? Can it be measured? While humankind has struggled with these questions for millennia, our project will focus on more modest but nonetheless ambitious and related goals. Inspired by recent developments in neuroscience and the potential role of fundamental concepts such as information integration and algorithmic complexity, we will study, model, quantify, and alter observable ...
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 8

 TERMINÉ 

Integrated Activities for the High Energy Astrophysics Domain (AHEAD)

Date du début: 1 sept. 2015, Date de fin: 28 févr. 2019,

We propose a set of integrated Activities in the High Energy Astrophysics Domain (AHEAD) in response to the INFRAIA-2014-2015 call Research Infrastructures for High EnergyAstrophysics.The overall objective of AHEAD is to integrate national efforts in high-energy Astrophysics and to promote the domain at the European level, to keep its community at the cutting edge of science and technology in this ...
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 26

 TERMINÉ 
Europe’s bioeconomy is expected to foster economic growth and to tackle significant societal challenges with less harmful environmental effects through innovative, sustainable and inclusive use of European forest resources. Increasing demand for biomass and other ecosystem goods and services calls for changes in forest-related policies at different levels and across different sectors. Accordingly, ...
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 37

 TERMINÉ 
The recent explosion of next generation sequencing (NGS) data has caught Europe unprepared and led to a critical shortage of computational biology expertise. As NGS methods are expected to become pervasive from basic science to personalised medicine there is an urgent need for highly skilled young scientists trained in both computational biology and experimental wet lab biology. Our network addres ...
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 11

 TERMINÉ 
The requirement for sustainable food production is a global issue to which the EU contributes as a major livestock producer. It is critical to improve animal production efficiency while sustaining environmentally friendly milk production. More profitable dairy production requires increased milk yield, cow health, longevity and fertility; reduced environmental footprint and optimised use of inputs. ...
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 17

 TERMINÉ 
...ack at the level of human resources is strongly related to the lacks in the higher education system, the improvement of which is object of our proposal by: a. increasing the capacity of Asian partner'university's staff in the area of food safety and quality, by sharing experiences and organising training courses.b. training them in "training engineering" (TE) methodology, encompassing 2 wide surve ...
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 13

 TERMINÉ 
Despite the advances in modernization and capacity building of the research landscapes of the Western Balkan countries, especially in universities, management of the human resources in research and science is still lagging behind the level of the practices and standards of the EU universities. The national funding of science in the WB countries is far below the ERA Lisbon targets, and it is projec ...
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 13

 TERMINÉ 
The EURAXESS TOP III consortium includes partners from almost all EURAXESS countries (either as beneficiaries or associated partners, from altogether 39 countries), in order to ensure the widest possible coverage as well as increased impact. The project has been divided into eight work packages. Two WPs are devoted to the development, testing and pilot introduction of new services on career develo ...
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 34

 TERMINÉ 
"This ITN TRANSMIC project brings together a group of universities, think-tanks, institutes, practitioners and high-level officials that all share a long-term interest in migration policies and citizenship issues and who have extensive academic and/or practical expertise in this field. Their inter- and multi-disciplinary knowledge and experience is pooled with the main objective of improving the E ...
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 8

 TERMINÉ 

Measurement and Architecture for a Middleboxed Internet (MAMI)

Date du début: 1 janv. 2016, Date de fin: 30 juin 2018,

Recent revelations about large-scale pervasive surveillance of Internet traffic have led to a rapidly expanding deployment of encryption in order to protect end-user privacy. At the same time, network operators and access providers rely on increasing use of in-network functionality provided by middleboxes and network function virtualization (NFV) approaches to improve network operations and manage ...
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 7

 TERMINÉ 

Human Brain Project Specific Grant Agreement 1 (HBP SGA1)

Date du début: 1 avr. 2016, Date de fin: 31 mars 2018,

Understanding the human brain is one of the greatest scientific challenges of our time. Such an understanding can provide profound insights into our humanity, leading to fundamentally new computing technologies, and transforming the diagnosis and treatment of brain disorders. Modern ICT brings this prospect within reach. The HBP Flagship Initiative (HBP) thus proposes a unique strategy that uses I ...
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 126

 TERMINÉ 
"Stratified clinical treatment interventions meeting patient-specific efficacy (pharmacodynamics) while at the same time lowering the risk of emergence of drug resistance (EDR) and minimizing adverse effects are particularly needed in Hospital-acquired and Ventilator-Associated pneumonia [HAP/VAP] where morbidity, mortality and health care costs remain high. β-lactam antibiotics are at the corners ...
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 13

 TERMINÉ 

Superfluidity: a super-fluid, cloud-native, converged edge system (SUPERFLUIDITY)

Date du début: 1 juil. 2015, Date de fin: 31 déc. 2017,

Superfluidity is “a state in which matter behaves like a fluid with zero viscosity”. Our project aims at achieving superfluidity in the network: the ability to instantiate services on-the-fly, run them anywhere in the network (core, aggregation, edge) and shift them transparently to different locations.The SUPERFLUIDITY project tackles crucial shortcomings in today’s networks: long provisioning ti ...
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 18

 TERMINÉ 
This project will establish a demonstration fleet of small passenger vehicles that builds on and expands existing hydrogen refuelling infrastructure. Three European regions will be participating in this effort: the UK (the Midlands and Plymouth), the Brussels area and Wallonia, and the Weser-Ems region in NorthWest Germany. Each of these regions will deploy a new hydrogen refuelling site to close ...
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 18

 TERMINÉ 

High-End cLimate Impacts and eXtremes (HELIX)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,

"With the target of limiting global warming to 2ºC increasingly difficult to achieve, policymakers, businesses and other decision-makers need to plan to adapt to changes in climate under higher levels of global warming. This requires coherent information on the future climate conditions, and the consequences of different adaptation actions. International negotiations on limiting global warming a ...
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 17

 TERMINÉ 
"Chronic inflammatory diseases of joints are major causes of disability in the ageing population. Osteoarthritis (OA) is one of the most common types of arthritis and a major cause of pain and disability in older individuals. OA is expected to place a heavy burden on European healthcare systems, as European citizens grow older. Cartilage damage in OA is detected radiographically by decreases in jo ...
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 15

 TERMINÉ 
"Power system reliability management means to take decisions under increasing uncertainty (for instance, related to renewable generation). It aims to maintain power system performance at a desired level, while minimizing the socio-economic costs of keeping the power system at that performance level. Seven TSOs (Belgium, Bulgaria, Czech Republic, Denmark, France, Iceland, Norway), together with ele ...
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 20

 TERMINÉ 

Joint Operation for Ultra Low Emission Shipping (JOULES)

Date du début: 1 juin 2013, Date de fin: 31 mai 2017,

Reducing emissions from shipping has increasingly become a challenge over the last years, both as a counter measure against global climate change and to protect local environments and population from waste, gas emissions and noise.This challenge has been documented both in policy papers, like the Europe 2020 initiative or the Transport White Paper, and in rules and regulations issued by IMO as wel ...
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 44

 TERMINÉ 
According to UN assessments, there are 214 million international migrants worldwide and another 740 million internal migrants . The OECD highlights that there seems little likelihood of substantial reductions in numbers of international migrants in the current decade . Rises in global population, new demographic trends including ageing population, environmental deterioration and an increased globa ...
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 8

 TERMINÉ 

Mechanisms and Treatment of Migraine and its Chronification (EUROHEADPAIN)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2017,

Migraine is a common brain disorder, typically characterised by recurring, incapacitating attacks of 1-3 days of severe headache, autonomic dysfunction, and sometimes aura symptoms. The disease affects 15% of all European citizens including children, ranks among the WHO top 12 of most disabling and undertreated disorders, and is responsible for the highest socio-economic burden of any brain ailmen ...
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 14

 TERMINÉ 
PROTECTED aims to develop expertise and protective capabilities against Endocrine Disruptors (EDs). EDs and their mixtures are a modern day health concern leading to failing ecological systems, poor agricultural production and health effects such as obesity, cancer and infertility. While analytical methods have advanced enormously, focus has been mainly on synthetic chemicals, overlooking emerging ...
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 10

 TERMINÉ 

Machine Learning for Personalized Medicine (MLPM2012)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

"Over the last decade, enormous progress has been made on recording the health state of an individual patient down to the molecular level of gene activity and genomic information – even sequencing a patient’s genome for less than 1000 dollars is no longer an unrealistic goal. However, the ultimate hope to use all this information for personalized medicine, that is to tailor medical treatment to th ...
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 11

 TERMINÉ 

Bottom-up Approaches to Machines dedicated to Bayesian Inference (BAMBI)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2016,

We propose a theory and a hardware implementation of probabilistic computation inspired by biochemical cell signaling. We will study probabilistic computation following three axes: algebra, biology, and hardware. In each case, we will develop a bottom-up hierarchical approach starting from the elementary components, and study how to combine them to build more complex systems. We propose Bayesian g ...
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 6

 TERMINÉ 

MULTI-valued and parallel molecular logic (MULTI)

Date du début: 1 sept. 2012, Date de fin: 29 févr. 2016,

MULTI replaces the familiar sequential model of computation that uses Boolean variables and combinational gates by logic operations that are executed in parallel on devices that have a built-in many state memory and whose inputs and outputs are multivalued. MULTI seeks to design, simulate and experimentally implement proof of principle devices on the atomic and molecular scale.MULTI refers to the ...
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 4

 TERMINÉ 

Policy-oriented marine Environmental Research in the Southern EUropean Seas (PERSEUS)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

The overall scientific objectives of PERSEUS are to identify the interacting patterns of natural and human-derived pressures on the Mediterranean and Black Seas, assess their impact on marine ecosystems and, using the objectives and principles of the Marine Strategy Framework Directive as a vehicle, to design an effective and innovative research governance framework based on sound scientific knowl ...
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 55

 TERMINÉ 
In the transition from a fossil based to a bio-based economy. it has become an important challenge to maximally close the nutrient cycles and migrate to a more sustainable resource management. both from an economical as an ecological perspective. Nutrient resources are rapidly depleting. significant amounts of fossil energy are used for the production of chemical fertilizers. whereas costs for ene ...
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 7