Plus de 40 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging with ‘Minimally-Invasive Segmental Artery Coil-Embolization’: A Randomized Controlled Multicentre Trial (PAPA-ARTIS)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,
Chronic aortic aneurysms are permanent and localized dilations of the aorta that remain asymptomatic for long periods of time but continue to increase in diameter before they eventually rupture. Left untreated, the patients’ prognosis is dismal, since the internal bleeding of the rupture brings about sudden death. Although successful treatment cures the disease, the risky procedures can result in ...
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26
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TERMINÉ
An Integrated European ‘Flagship’ Program Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st Century (EU-ToxRisk)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2021,
The vision of EU-ToxRisk is to drive a paradigm shift in toxicology towards an animal-free, mechanism-based integrated approach to chemical safety assessment. The project will unite all relevant disciplines and stakeholders to establish: i) pragmatic, solid read-across procedures incorporating mechanistic and toxicokinetic knowledge; and ii) ab initio hazard and risk assessment strategies of chemi ...
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43
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TERMINÉ
Small vessel diseases in a mechanistic perspective: Targets for InterventionAffected pathways and mechanistic exploitation for prevention of stroke and dementia (SVDs-at-target)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,
Stroke and dementia rank among the most pressing health issues in Europe. Cerebral small vessel diseases (SVDs) have emerged as a central link between these two major co-morbidities. SVDs account for more than 30% of strokes and at least 40% of dementia cases. They encounter multiple distinct diseases that can be separated based on their underlying genetic defects, risk factors, and clinical prese ...
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14
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TERMINÉ
Role of European Mobility and its Impacts in Narratives, Debates and EU Reforms (REMINDER)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,
The overarching goal of the project is to understand the economic, social, institutional and policy factors that have shaped the impacts of free movement and public debates about it. It aims to help European policymakers develop policy responses that inspire public trust, ensure the fairness and sustainability of free movement, and maintain inclusive policies that reduce inequalities across the co ...
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14
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TERMINÉ
OpenRiskNet: Open e-Infrastructure to Support Data Sharing, Knowledge Integration and in silico Analysis and Modelling in Risk Assessment (OpenRiskNet)
Date du début: 1 déc. 2016, Date de fin: 30 nov. 2019,
Toxicology and risk assessment are undergoing a paradigm shift, from a phenomenological to a mechanistic discipline based on in vitro and in silico approaches that represent an important alternative to classical animal testing applied to the evaluation of chronic and systemic toxicity risks. Large databases and highly sophisticated methods, algorithms and tools are available for different tasks su ...
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14
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TERMINÉ
European Network of Research Ethics and Research Integrity (ENERI) (ENERI)
Date du début: 1 sept. 2016, Date de fin: 31 août 2019,
The “European Network of Research Ethics and Research Integrity” (ENERI) establishes an operable platform of actors in the fields of research ethics and research integrity.The reliability and credibility of research and science do not depend only on its excellence and productivity but also on the players’ awareness of highest standards of ethics in research and commitment to a responsible conduct ...
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11
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TERMINÉ
Expanding the industrial use of Robust Oxidative Biocatalysts for the conversion and production of alcohols (ROBOX) (ROBOX)
Date du début: 1 avr. 2015, Date de fin: 31 mars 2019,
Oxygen functionalities are key functional groups in many of today’s chemicals and materials. The efficient introduction of oxygen-functionalities into raw materials are key chemical transformations in bulk and fine chemicals. Innovative bio-catalytic oxidation routes using molecular oxygen (from air) under benign and mild (pH) conditions such as ambient temperature and pressure can greatly improve ...
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20
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TERMINÉ
AN INNOVATIVE CAUSAL THERAPY FOR ALLERGY: SAFE AND RAPID INDUCTION OF AN ANTI-INFLAMMATORY IMMUNE RESPONSE USING A MUTANT HYPOALLERGEN AND VITAMIN D3 (BM4SIT)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,
Allergy is the most prevalent chronic inflammatory disease, having great socio-economic impact. Chronic lifelong dependency on symptomatic drugs is an expensive reality for the vast majority of allergy sufferers. Allergen-specific immunotherapy is the only causal and effective treatment targeting the underlying immune mechanism in a more cost-effective way. Yet, long treatment duration and risk of ...
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10
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TERMINÉ
Heart OMics in AGEing (HOMAGE)
Date du début: 1 févr. 2013, Date de fin: 31 janv. 2019,
As more people survive into old age, the prevalence of heart failure (HF), one of the most common and debilitating diseases in older people, will rise still further. Delaying or preventing HF will have great benefit to those at personal risk, their families, society and the economy. HOMAGE aims to provide a biomarker (BM) approach that will a) help identify i. patients at high risk of developing ...
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22
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TERMINÉ
Aggression subtyping for improved insight and treatment innovation in psychiatric disorders (AGGRESSOTYPE)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,
Aggression is a basic physiological trait with important roles throughout evolution, both in defence and predation. When expressed in humans in the wrong context, aggression leads to maladjustment, social impairment and crime. Despite this, knowledge about aggression aetiology is limited and current treatment strategies are insufficient. Contingent to a subdivision into impulsive and instrumental ...
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27
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TERMINÉ
Human Brain Project Specific Grant Agreement 1 (HBP SGA1)
Date du début: 1 avr. 2016, Date de fin: 31 mars 2018,
Understanding the human brain is one of the greatest scientific challenges of our time. Such an understanding can provide profound insights into our humanity, leading to fundamentally new computing technologies, and transforming the diagnosis and treatment of brain disorders. Modern ICT brings this prospect within reach. The HBP Flagship Initiative (HBP) thus proposes a unique strategy that uses I ...
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126
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TERMINÉ
European Clinical Research Infrastructures Network - Integrating Activity (ECRIN-IA)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2017,
ECRIN is a distributed ESFRI-roadmap pan-European infrastructure designed to support multinational clinical research, making Europe a single area for clinical studies, taking advantage of its population size to access patients. Servicing multinational trials started during its preparatory phase, and it now applies for an ERIC status by 2011. The ERIC budget will be restricted to core activities re ...
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48
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TERMINÉ
TOWARDS SAFE AND EFFECTIVE IMMUNOTHERAPY OF PERSISTENT LIFE-THREATENING FOOD ALLERGIES (FAST)
Date du début: 1 sept. 2008, Date de fin: 31 mai 2017,
The FAST project aims at the development of safe and effective treatment of food allergies. It targets persistent and severe allergy to fish and fruit. Besides persistence and severity, this choice is based on prevalence and the importance of these foods for a healthy diet. Classical allergen-specific immunotherapy (SIT) for treatment of food allergy using subcutaneous injections with food extract ...
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19
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TERMINÉ
BBMRI - Large Prospective Cohorts (BBMRI-LPC)
Date du début: 1 févr. 2013, Date de fin: 31 janv. 2017,
In recent years, biomedical research has crossed international borders in large, collaborative studies showing the value of multidisciplinarity and scale advantage. This has yielded valuable insights and some led to new and better medicines and treatments for diseases. However, disease-focused studies provide less insight in the real disease onset, the relative disease burden in the population, an ...
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36
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TERMINÉ
Boosting the Impact of Social Innovation in Europe through Economic Underpinnings (SIMPACT)
Date du début: 1 janv. 2014, Date de fin: 31 déc. 2016,
SIMPACT advances understanding of social innovation’s economic dimensions, creating new concepts, models and instruments for policy makers, innovators, investors and intermediaries. It systematically investigates how social innovations can enable the most vulnerable in society to become economic assets, integrating critical analysis of current and previous work with future-oriented methodologies, ...
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12
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TERMINÉ
The Human Brain Project (HBP)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,
Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the ...
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116
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TERMINÉ
Europäische Moblitäten in Laboren
Date du début: 1 juin 2014, Date de fin: 31 mai 2016,
Project background
Lise-Meitner-Schule is a vocational school/technical college in Berlin, Germany. We are specialized in the training of people who are going to work in laboratories and science orientated industry (Biology, Chemistry, Physics, Pharmacy, Micro Technology).
Since more than 20 years the school is conducting EU projects (Leonardo da Vinci Mobilities, Pilot Projects and Innovation Tra ...
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15
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TERMINÉ
Markers for Sub-Clinical Cardiovascular Risk Assessemnt (EU-MASCARA)
Date du début: 1 déc. 2011, Date de fin: 31 mai 2016,
EU-MASCARA is a collaborative project that aims to improve diagnosis of cardiovascular diseases and prediction of cardiovascular risk by analysing a panel of biomarkers. EU-MASCARA aims to examine genetic, proteomic and metabolomic markers together with markers of inflammation, oxidative stress and cardiac remodelling to study their incremental diagnostic and predictive value over and above existi ...
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16
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TERMINÉ
The Open Pharmacological Concepts Triple Store (OPEN PHACTS)
Date du début: 1 mars 2011, Date de fin: 29 févr. 2016,
Drug discovery is data-hungry and all major pharmaceutical companies maintain extensive in-house instances of public data alongside internal. Analysis and hypothesis generation for drug-discovery projects requires assembly, overlay and comparison of data from many sources, requiring shared identifiers and common semantics. Expression profiles need to be overlaid with gene or pathway identifiers an ...
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32
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TERMINÉ
Predicting long-term toxic effects using computer models based on systems characterization of organotypic cultures (NOTOX)
Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,
"NOTOX will develop and establish a spectrum of systems biological tools including experimental and computational methods for i) organotypic human cell cultures suitable for long term toxicity testing and ii) the identification and analysis of pathways of toxicological relevance. NOTOX will initially use available human HepaRG and primary liver cells as well as mouse small intestine cultures in 3D ...
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13
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TERMINÉ
Detection of endpoints and biomarkers of repeated dose toxicity using in vitro systems (DETECTIVE)
Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,
"Assessment of repeated dose toxicity is a standard requirement in human safety evaluation and relies on animal testing as no alternatives are currently accepted for regulatory purposes. An integrated research strategy for the replacement of animal tests needs to comprise the development of biomarkers of long-term toxicity in human target cells. To this aim, the DETECTIVE project will set up a scr ...
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15
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TERMINÉ
Multidimensional Impact of the Low-carbon European Strategy on Energy Security, and Socio-Economic Dimension up to 2050 perspective (MILESECURE-2050)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2015,
The main objective of the project is to explore, identify, analyze and evaluate multidimensional impact of European low-carbon strategy on energy security and socio-economic dimension up to 2050 perspective. Energy transition towards a low carbon economy and society have to be considered as a process by nature that it is not only the mere result of intentional actions but the product of the intera ...
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11
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TERMINÉ
The European Network for Translational Research in Atrial Fibrillation (EUTRAF)
Date du début: 1 nov. 2010, Date de fin: 31 oct. 2015,
"The initiation and perpetuation of atrial fibrillation (AF) can be regarded as a complication of a progressive transformation of the structure and functional properties of the atria. This transformation is the result of complex and multiple changes at the molecular, cellular and organ levels which interact to form the basis for proarrhythmic mechanisms in AF. Numerous individual and environmental ...
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20
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TERMINÉ
Recruitment and activation of brown adipocytes as preventive and curative therapy for type 2 diabetes (DIABAT)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2015,
"The DIABAT project will employ knowledge of the function, dysfunction and physiological regulation of brown adipocytes to develop innovative therapeutic and preventive strategies for type 2 diabetes. Brown adipose tissue (BAT) is currently a worldwide recognized target to combat obesity and diabetes due to last years re-discovery of functional BAT in adult humans by several of the members of the ...
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22
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TERMINÉ
Protecting the food chain from prions: shaping European priorities through basic and applied research (PRIORITY)
Date du début: 1 oct. 2009, Date de fin: 30 sept. 2014,
"Bovine Spongiform Encephalopathy (BSE) started, 20 years ago, a devastating health and food crisis throughout Europe. Classical BSE is now under control as a result of the meat and bone meal ban. However, tonsil analyses suggest that there may be an alarmingly high number of asymptomatic PrPSc positive cases. Transmission through blood transfusion is another important concern, as are recent “atyp ...
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21
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TERMINÉ
European Research Ethics Committees’ Network (EURECNET)
Date du début: 1 mars 2011, Date de fin: 31 août 2014,
EURECNET is a network that brings together national REC associations, networks or comparable initiatives but also other bodies relevant in the field of research involving human participants like National Ethics Councils and the European Commission’s ethical review system. Such a network forms the infrastructural basis to promote awareness of specific working practices of RECs across Europe, to enh ...
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22
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TERMINÉ
European Framework for Measuring Progress (e-Frame)
Date du début: 1 janv. 2012, Date de fin: 30 juin 2014,
Within the framework of the Work Programme 2011 on Socio-economic Science and Humanities e-Frame project builds on the latest political directions of the European Commission, in particular the priorities identified in the Europe 2020 strategy. The project will focus on the following general objectives: stocktaking of available results and of ongoing research activities on progress measurement; fos ...
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19
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TERMINÉ
EUropean Cross Border Care Collaborations Short Title: CrossEurope (EUCBCC)
Date du début: 1 mai 2010, Date de fin: 31 oct. 2013,
"EUCBCC aims to facilitate a process whereby Europe's citizens can make informed choices about whether to seek health care in another Member State and, if they so choose, to ensure that the admin and clinical processes are straightforward and ensure continuity of care. It takes as its starting point the recent draft Directive on Patients' Rights, augmented by the existing body of research on cross ...
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15
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TERMINÉ
Improving health services for European citizens with dementia: Development of best practice strategies for the transition from ambulatory to institutional long-term care facilities (RightTimePlaceCare)
Date du début: 1 janv. 2010, Date de fin: 30 sept. 2013,
Given the increasing number of patients/consumers with dementia, political action is urgently required to prepare the health care services throughout Europe to deliver cost effective high quality long-term care to people concerned. Currently there is a lack of clinical research data of patients/consumers and informal caregivers to develop best practice strategies for long-term care. RightTimePlace ...
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8
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TERMINÉ
RICHE – a platform and inventory for child health research in Europe (RICHE)
Date du début: 1 févr. 2010, Date de fin: 31 juil. 2013,
"The European Commission and other funding agencies make a large investment in child health research. The health of our children is satisfactory, but there are serious concerns, for example, obesity, mental health, alcohol abuse, and sexuality. We know that there are strong links between the health of young people and their social inclusion and level of education. Our objective is to establish a s ...
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27
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TERMINÉ
Advancing knowledge-intensive entrepreneurship and innovation for growth and social well-being in Europe (AEGIS)
Date du début: 1 janv. 2009, Date de fin: 30 sept. 2012,
The proposed research project will study the interactions between knowledge, economic growth and social wellbeing in Europe. It focuses on knowledge-intensive entrepreneurship as a necessary mechanism and an agent of change mediating between the creation of knowledge and its transformation into economic activity. Knowledge-intensive entrepreneurship is perceived herein as a core interface between ...
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22
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TERMINÉ
IT Future of Medicine (ITFoM)
Date du début: 1 mai 2011, Date de fin: 30 avr. 2012,
Data-rich, individualised medicine poses unprecedented challenges for IT, in hardware, storage and communication. We propose a data-driven, individualised medicine of the future, based on molecular/physiological/anatomical data from individual patients. We shall make general models of human pathways, tissues, diseases and ultimately of the human as a whole. Individualised versions of the models, ...
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25
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TERMINÉ
Good Practices in Innovation Support Measures for SMEs: facilitating transition from the traditional to the knowledge economy (GPrix)
Date du début: 1 déc. 2009, Date de fin: 29 févr. 2012,
The GPrix project - Good Practices in Innovation Support Measures for SMEs: facilitating transition from the traditional to the knowledge economy - will provide a comprehensive insight into the design and implementation of SME research and innovation support programmes, actions, services and networks especially at national and regional level, and on its impact, in particular amongst the traditiona ...
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7
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TERMINÉ
Inter-connected European Information and Documentation System for Ethics and Science: European Ethics Documentation Centre (ETHICSWEB)
Date du début: 1 juin 2008, Date de fin: 31 août 2011,
"It is the overall aim of ETHICSWEB to stimulate an enhanced democratic debate on ethical issues of science and to promote a more engaged and informed public. Therefore, existing information and documentation systems will be connected to allow and ensure an easy access to comprehensive information on science and ethics. At the same time sophisticated tools, both technical and semantic, will be app ...
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16
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TERMINÉ
The mechanisms of cardiovascular risks after low radiation doses (CARDIORISK)
Date du début: 1 févr. 2008, Date de fin: 30 juin 2011,
"Recent epidemiologic evidence suggests that moderate and low radiation doses to the heart may result in a moderate, but significant increase in cardiovascular mortality. So far, the pathogenesis of radiation induced heart disease has not been studied in detail. Pathohistologic studies suggest that microvascular damage plays a crucial role in the development of radiation induced cardiovascular dis ...
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14
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TERMINÉ
EDGE: EDucation & GEnder
Date du début: 1 oct. 2011,
Im Juli 2009 wurde durch die Europäische Kommission der Bericht ‚Gender and Education‘ veröffentlicht. Odile Quintin, Director-General des Directorate-General for Education and Culture resümiert, das „All school and college programmes, from pre-school to university, including professional and occupational training courses, should involve a core module on gender equality.” Das Projekt richtet sich ...
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13
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TERMINÉ
S1-L14 Europe & South Africa Partnership for Human Development II
Date du début: 15 juil. 2011,
The EUROSA II partnership aims to contribute to redressing past inequities and imbalances and to improve the participation rate of historically disadvantaged individuals in higher education. Capacity building and human development, with specific attention to South African’s designated groups, through master, PhD and staff mobility from South Africa to Europe are at the core of the project. The pri ...
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17
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TERMINÉ
European Master in Neuroscience
Date du début: 1 oct. 2009,
Brain disease, psychiatric and neurologic diseases, combined represents a large social and economic burden in Europe. An analysis by the European Brain Council in 2005, estimated the total costs of brain disease throughout Europe in 2004 to be Euro 386 billion. That burden is set to grow, mainly due to the fact that the European population is ageing. The need for innovative treatments has never be ...
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9
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TERMINÉ
Gender-Medicine
Date du début: 1 oct. 2009,
Gender determines the outcome of numerous wide-spread diseases. Myocardial infarction, heart failure (HF), diabetes, neuropsychiatric, musculoskeletal, renal and others differ significantly between women and men. Side effects of frequently used drugs, use of prevention and rehabilitation depend on gender. A large imbalance of gender knowledge between different European regions exists. Yet, a syst ...
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7
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TERMINÉ
Trans-Atlantic Neuroscience TEaching Network
Date du début: 1 oct. 2009,
This program aims to increase exchange opportunities for 24 European Neuroscience students to Canadian Universities. There is a clear synergism with respect to research areas and research culture in the Universities in this consortium. The aim is to provide a challenging study abroad program for students, extend existing exchange programs and increase mutual awareness of teaching programs and meth ...
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