4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
REgenerative therapy of intervertebral disc: a double blind phase 2b trial of intradiscal injection of mesenchymal stromal cells in degenerative disc disease of the lomber SPINE unresponsive to conventional therapy (RESPINE)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
The World Health Organisation (WHO) has included low back pain in its list of twelve priority diseases. Notably, Degenerative disc disease (DDD) presents a large, unmet medical need which results in a disabling loss of mechanical function. Today, no efficient therapy is available. Chronic cases often receive surgery, which may lead to biomechanical problems and accelerated degeneration of adjacent ...
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18
Participants partenaires
TERMINÉ
Stem cells for Biological Assays of Novel drugs and prediCtive toxiCology (StemBANCC) (STEMBANCC)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2017,
StemBANCC, comprising internationally renowned investigators, is ideally positioned to deliver a unique European biorepository and drug discovery pipeline based upon human induced pluripotent stem cells (hiPSC). This unrivalled opportunity will address the pressing therapeutic need in neurodegeneration, neurodysfunction and diabetes. We have immediate access to richly phenotyped subjects with a we ...
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38
Participants partenaires
TERMINÉ
A Unique Pancreatic Human Beta Cells to revolutionize the Diabetes Drug Discovery (BETASCREEN)
Date du début: 1 août 2016, Date de fin: 31 janv. 2017,
Univercell Biosolutions (UB) is a pioneering biotech company providing unique human cell models to accelerate and secure pharmaceutical products. UB is generating 1 M€ turnover in 2015 selling its first generation of human beta cell lines to 10 world pharma industry leaders.Pharmas rentability is decreasing facing to high regulatory pressure and low clinical predictability on human. The rate of cl ...
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1
Participant partenaire
TERMINÉ
A bioartificial pancreas to treat type 1 diabetes: optimization of cell survival and function in preclinical and clinical phases (BIOSID)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,
MAILPAN (MAcroencapsulation of PANcreatic Islets) is a prototype of bioartificial pancreas usable in the human designed to treat type 1 diabetic patients. The prototype was developed along different stages since 1996 and led to the creation of the SME called Defymed in 2011. Next step is now to bring the prototype to the pre-clinical and clinical phases necessary to the ensuing commercialization o ...
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