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 TERMINÉ 
Land, food, energy, water and climate are interconnected, comprising a coherent system (the ‘Nexus’), dominated by complexity and feedback. The integrated management of the Nexus is critical to secure the efficient and sustainable use of resources. Barriers to a resource efficient Europe are policy inconsistencies and incoherence, knowledge gaps, especially regarding integration methodologies and ...
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 28

 TERMINÉ 
The objective of SponGES is to develop an integrated ecosystem-based approach to preserve and sustainably use vulnerable sponge ecosystems of the North Atlantic. The SponGES consortium, an international and interdisciplinary collaboration of research institutions, environmental non-governmental and intergovernmental organizations, will focus on one of the most diverse, ecologically and biologicall ...
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 19

 TERMINÉ 
The overarching goal of the project is to understand the economic, social, institutional and policy factors that have shaped the impacts of free movement and public debates about it. It aims to help European policymakers develop policy responses that inspire public trust, ensure the fairness and sustainability of free movement, and maintain inclusive policies that reduce inequalities across the co ...
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 14

 TERMINÉ 
Toxicology and risk assessment are undergoing a paradigm shift, from a phenomenological to a mechanistic discipline based on in vitro and in silico approaches that represent an important alternative to classical animal testing applied to the evaluation of chronic and systemic toxicity risks. Large databases and highly sophisticated methods, algorithms and tools are available for different tasks su ...
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 14

 TERMINÉ 

EPOS Implementation Phase (EPOS IP)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2019,

The nations of Europe are distributed around some of the most complex and dynamic geological systems on the planet and understanding these is essential to the security of livelihoods and economic power of Europeans. Many of the solutions to the grand challenges in the geosciences have been led by European scientists – the understanding of stratigraphy (the timing and distribution of layers of sedi ...
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 48

 TERMINÉ 
"The objective of DEPRIVEDHOODS is to come to a better understanding of the relationship between socio-economic inequality, poverty and neighbourhoods. The spatial concentration of poverty within cities is of great concern to national governments, partly based on a belief in neighbourhood effects: the idea that living in deprived neighbourhoods has an additional negative effect on residents’ life ...
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 5

 TERMINÉ 

Marine Renewable Energy Research Infrastructure (MARINERGI)

Date du début: 1 janv. 2017, Date de fin: 30 juin 2019,

The objective of MARINERG-i is to become the leading internationally distributed infrastructure in the Marine Renewable Energy (MRE) sector. Its integrated nature and co-ordinated approach will accelerate the research development and deployment of offshore wind, wave, tidal and combined energy technologies and help maintain Europe as a global leader in this industry. In addition MARINERG-i wil ...
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 13

 TERMINÉ 

Integrated view on disruptions of early brain development (BRAINVIEW)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

Early onset neurodevelopmental disorders such as autism spectrum disorders (ASD) and attention-deficit hyperactivity disorder (ADHD) are rather common, and affect more than 30 million children in Europe. The disorders carry a huge burden to the patients and their families and to society in general. This burden is linked to their chronic course and the absence of curative treatments. These neurodev ...
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 12

 TERMINÉ 

MIME - MOBILITY AND INCLUSION IN MULTILINGUAL EUROPE (MIME)

Date du début: 1 mars 2014, Date de fin: 31 août 2018,

Using an innovative interdisciplinary approach, MIME will generate an organised body of policy-relevant propositions addressing the full range of questions raised in the call. Our aim is to identify the language policies and strategies that best combine “mobility” and “inclusion”.MIME emphasises complementarity between disciplines, and brings together researchers from sociolinguistics, political s ...
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 23

 TERMINÉ 
The data generated in the health domain is coming from heterogeneous, multi-modal, multi-lingual, dynamic and fast evolving medical technologies. Today we are found in a big health landscape characterized by large volume, versatility and velocity (3Vs) which has led to the evolution of the informatics in the big biodata domain. AEGLE project will build an innovative ICT solution addressing the who ...
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 14

 TERMINÉ 
In the coming decade a significant number of the 500.000.000 European (EU/EEA) citizens will have their genome determined routinely. This will be complemented with much cheaper (currently ~20 Euro per measurement) acquisition of the metabolome of biofluids (e.g. urine, saliva, blood plasma) which will link the genotype with metabolome data that captures the highly dynamic phenome and exposome of p ...
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 17

 TERMINÉ 

Health Care Work Exchange 2016

Date du début: 1 juin 2016, Date de fin: 31 mai 2018,

The “Health Care Work Exchange 2016” project will enable 100 apprentices and students of health care vocational schools from 1 June 2016 to 31 May 2018 to carry out an internship in all countries participating in the ERASMUS+ Mobility Program. Apprentices and students in the fields of nursing, midwifery, physical therapy, occupational therapy, speech therapy, special education and in medical techn ...
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 39

 TERMINÉ 

Human Brain Project Specific Grant Agreement 1 (HBP SGA1)

Date du début: 1 avr. 2016, Date de fin: 31 mars 2018,

Understanding the human brain is one of the greatest scientific challenges of our time. Such an understanding can provide profound insights into our humanity, leading to fundamentally new computing technologies, and transforming the diagnosis and treatment of brain disorders. Modern ICT brings this prospect within reach. The HBP Flagship Initiative (HBP) thus proposes a unique strategy that uses I ...
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 126

 TERMINÉ 
The ageing of the European population represents a rapidly rising social and economic challenge. Especially cardiovascular morbidity increases with age, but unfortunately, elderly patients are often difficult to diagnose due to confounding factors, leading to uncertainties in clinical decision making with huge impact on patients’ outcomes. Hence, there is an unmet need for novel biomarkers for mor ...
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 22

 TERMINÉ 
The AIDA project aims to answer the question of clinical effectiveness and optimal dosing of 5 off-patent antibiotics for infections caused by multiple drug resistant (MDR) bacteria in three randomized controlled clinical trials. In an era of increasing emergence of drug resistance (EDR) and lack of new antibiotics, old off- patent antibiotics are increasingly being prescribed to patients. However ...
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 19

 TERMINÉ 

Mutanome Engineered RNA Immuno-Therapy (MERIT)

Date du début: 1 juin 2013, Date de fin: 30 nov. 2017,

The Mutanome Engineered RNA Immuno-Therapy (MERIT) project aims to clinically translate and industrially validate a pioneering RNA-based immunotherapy approach to target the individual tumour antigen signature. MERIT focuses on previous inventions, fits into the overall business and innovation needs of the partners, and addresses triple-negative breast cancer patients with high medical need. The M ...
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 5

 TERMINÉ 

Nanometrology Standardization Methods for Magnetic Nanoparticles (NANOMAG)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,

The NanoMag project is to improve and redefine existing analyzing methods and in some cases, to develop new analyzing methods for magnetic nanostructures. Using improved manufacturing technologies we will synthesize magnetic nanoparticles with specific properties that will be analyzed with a multitude of characterization techniques (focusing on both structural as well as magnetic properties) and b ...
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 18

 TERMINÉ 
Drug development in TB requires new integrated methods to transition the novel combination regimens needed to shorten first-line therapy and combat multi-drug resistance. Although new agents are emerging, the path to registration of such regimens remains uncertain while capacity for pivotal trials is limited. Selection and optimization of drug combinations for development depends on preclinical sy ...
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 23

 TERMINÉ 

Entrepreneurship, Modernization and Innovation in SoutH Africa

Date du début: 15 oct. 2015, Date de fin: 14 oct. 2017,

Based on a previous EU project on innovation in South Africa we realized there was a need for a capacity building project in the region. As previous projects had focused on mobility of students and staff, we wanted to create a project that would train and support the university staff in developing innovation in their universities.We put together a set of models which would affect employment of gra ...
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 9

 TERMINÉ 

Analytical Research In ADME profiling (ARIADME) (ARIADME)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

The integration of absorption, distribution, metabolism and excretion (ADME) profiling into early drug discovery has been put forward as a strategy for reducing drug candidate attrition. Europe is challenged to develop novel ADME screening methodologies with increased efficiency and predictive power to profile the multitude of lead compounds currently being generated. The principal objective of th ...
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 6

 TERMINÉ 

Oral biopharmaceutics tools (ORBITO)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2017,

The OrBiTo project will deliver novel methods and a framework for rational application of predictive biopharmaceutics tools for oral drug delivery. This will be achieved through novel propsective studies to define new methodlogies which will be validated using historical datasets from EFPIA partners. A combination of high quality in vitro or in silico characterizations of API and formulations will ...
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 28

 TERMINÉ 

DRIVING RE-INVESTMENT IN R&D AND RESPONSIBLE ANTIBIOTIC USE (DRIVE-AB)

Date du début: 1 oct. 2014, Date de fin: 30 sept. 2017,

Antimicrobial resistance (AMR) is widespread. Its global human and economic burden is tremendous and increasing annually. Yet today only a few pharmaceutical companies retain active antibacterial drug discovery programmes. While the elaboration of antibiotics with novel mechanisms of action is scientifically complex, the chief challenge is diminishing incentives. Pre-market regulatory requirements ...
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 27

 TERMINÉ 
The iTERM ITN (4 companies, 6 universities) will deliver 12 early stage researchers (ESR) and 1 experienced researcher (ER) trained in imaging, material science, and tissue engineering & regenerative medicine (TERM). For the aging population in the EU donor material is often not available, and artificial tissue needs to be developed to replace and repair damaged tissues. New smart materials have b ...
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 8

 TERMINÉ 
Today, rational use of antibiotics is one the most important public health issues regarding both the control of communicable diseases and the control of increasing health expenditures around the World. The antibiotic consumption rate in Turkey is one of the highest among European countries. Studies show that international migrants from Turkey also show similar cultural characteristics, regarding t ...
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 7

 TERMINÉ 
"The strong temporal dynamics of the East African landscape and natural-resource distributions have always encouraged people to innovate and adapt to changing conditions. However, increasing population growth, changes in patterns of land tenure, industrialization, weak systems of governance, and global climate change have exacerbated previously localized environmental problems such as soil erosion ...
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 7

 TERMINÉ 
Cardiogenic shock (CS) complicating acute myocardial infarction (AMI) represents a major European health care concern with mortality rates between 40-70%. Approximately 70-80% of these patients present with multivessel disease defined as coronary lesions in more than one vessel. The clinician is faced with the decision to either 1) intervene only on the culprit lesion acutely responsible for the i ...
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 23

 TERMINÉ 

Health Care Work Exchange 2015

Date du début: 1 juin 2015, Date de fin: 31 mai 2017,

From 1.6.2015 to 31.5.2017 the project “Health Care Work Exchange 2015” will offer 100 apprentices and students of health care vocational schools an opportunity to carry out an internship in all countries participating in ERASMUS+. Foremost apprentices and students in the fields of nursing, midwifery, physical therapy, occupational therapy, speech therapy, special education and in medical technica ...
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 38

 TERMINÉ 
The main objective of GUIDEnano is to develop innovative methodologies to evaluate and manage human and environmental health risks of nano-enabled products, considering the whole product life cycle. A strategy to identify hot spots for release of nanomaterials (NMs) will be followed by decision trees to guide on the use of (computational) exposure models and, when necessary, design of cost-effecti ...
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 34

 TERMINÉ 

Enhanced European Coordination for Accelerator Research & Development (EUCARD-2)

Date du début: 1 mai 2013, Date de fin: 30 avr. 2017,

Research accelerators are facing important challenges that must be addressed in the years to come: existing infrastructures are stretched to all performance frontiers, new world-class facilities on the ESFRI roadmap are starting or nearing completion, and strategic decisions are needed for future accelerators and major upgrades in Europe.While current projects concentrate on their specific objecti ...
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 40

 TERMINÉ 

Integrated DEsign and AnaLysis of small population group trials (IDEAL)

Date du début: 1 nov. 2013, Date de fin: 30 avr. 2017,

There exist more than 7000 rare diseases worldwide and the European Society of Paediatric Oncology stated that 75% of rare diseases affect children and 30% of rare disease patients die before the age of five. Usual statistical methods for proving efficacy and safety of therapies fail to provide cost-efficient and reliable results in small populations. There is a pressing need to integrate a broad ...
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 10

 TERMINÉ 
Drug delivery systems are a matter of intensive scientific investigation and technological developments. They are necessary since many active pharmaceutical ingredients to be employed in therapy, diagnostics or vaccination cause serious side effects when distributed non-specifically. Without a drug delivery system, the active pharmaceutical ingredients may accumulate in healthy and sensitive tissu ...
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 4

 TERMINÉ 

BeTheCuRE (BTCURE)

Date du début: 1 avr. 2011, Date de fin: 31 mars 2017,

BTCure is based on the recognition that RA is a heterogeneous disease where a major subset involves adaptive immunity, and that animal models have to develop the line with the different subsets of the human diseases in order to be optimally used for drug discovery and drug evaluation. Our aim is to develop an understanding of the early process in human arthritis subsets and the animal models that ...
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 41

 TERMINÉ 

Engine Breakthrough Components and Subsystems (E-BREAK)

Date du début: 1 oct. 2012, Date de fin: 31 mars 2017,

Future aero engines will need to be more efficient and contribute to the reduction on environmental impact of air transportation. They must reach some standards of performance by reducing emissions and creating some savings on operation costs.EIMG consortium has launched since several years some initiatives to develop future engines in the frame of the European Committee research programmes.Within ...
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 48

 TERMINÉ 
Prediction-ADR aims to discover the genetic factors predisposing patients to adverse drug reactions (ADRs) from cardiovascular disease (CVD) drugs. This will be achieved by assembling a consented blood bank and DNA for a population of ~500 cases of ACEi induced angioedema and statin induced myopathy defined using a standardised phenotypic criteria. An innovative next generation sequencing strategy ...
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 7

 TERMINÉ 

BBMRI - Large Prospective Cohorts (BBMRI-LPC)

Date du début: 1 févr. 2013, Date de fin: 31 janv. 2017,

In recent years, biomedical research has crossed international borders in large, collaborative studies showing the value of multidisciplinarity and scale advantage. This has yielded valuable insights and some led to new and better medicines and treatments for diseases. However, disease-focused studies provide less insight in the real disease onset, the relative disease burden in the population, an ...
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 36

 TERMINÉ 
Background:In current drug safety education and training in Europe, an integrative and translational approach is lacking. This shortfall has been identified by EUFEPS. The IMI (‘Strategic Research Agenda’), the FDA and the EMEA have also characterised this fact as a crucial gap in the education and training of scientists evaluating the safety of drug candidates and new medicines. Scope and objecti ...
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 34

 TERMINÉ 
An ideal intervention in a chronic inflammatory disease such as Rheumatoid Arthritis (RA) would be a preventive one. In order to develop preventive strategies and therapies two key developments need to occur: (1) Biomarkers need to be identified that can be used to predict an individual’s risk of developing RA. (2) Modifiable disease mechanisms need to be identified and characterized in the early ...
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 17

 TERMINÉ 

The Human Brain Project (HBP)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the ...
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 116

 TERMINÉ 

Development of RApid Point-of-Care test Platforms for Infectious Diseases (RAPP-ID)

Date du début: 1 avr. 2011, Date de fin: 30 sept. 2016,

RAPP-ID (“Development of RApid Point-of-Care test Platforms for Infectious Diseases”) will develop a Point-of-Care Test (POCT) for rapid (hospital
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 20

 TERMINÉ 

Drug Disease Model Resources (DDMORE)

Date du début: 1 mars 2011, Date de fin: 31 août 2016,

Model based-drug development (MBDD) is accepted as a vital approach in understanding patient risk/benefit and attrition. At the core of MBDD lies Modelling and Simulation (M&S), a technology providing the basis for informed, quantitative decision-making.M&S facilitates the continuous integration of available information related to a drug or disease into constantly-evolving mathematical models capa ...
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 28