Plus de 40 projets européens trouvés
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TERMINÉ
Novel Quantum Emitters monolithically grown on Si, Ge and III-V substrates (4PHOTON)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
We propose to forge a partnership between the leading European groups working on the next generation of solid state quantum emitters based on novel growth methods such as Droplet Epitaxy. Future, practical Nano-photonics and Quantum Circuits applications demand semiconductor quantum dots that can be grown on substrates with different lattice parameters (Si, Ge, GaAs), different substrate orientati ...
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11
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TERMINÉ
Mechanisms of Evasive Resistance in Cancer (MERiC)
Date du début: 1 mai 2014, Date de fin: 30 avr. 2020,
Cancer is a major health problem due to the failure of current therapies to effectively eradicate the disease. Alternative signaling pathways compensate for a therapeutically targeted pathway, a process referred to as 'evasive resistance'. The identities of the alternative signaling pathways and functional interconnections that underlie evasive resistance remain widely unknown. We propose to integ ...
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3
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TERMINÉ
OPtimising thERapy to prevent Avoidable hospital admissions in the Multimorbid elderly (OPERAM)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,
Most older adults have multiple chronic diseases (multimorbidity) and multiple medications (polypharmacy). However, multimorbid patients are often excluded from clinical trials and most guidelines address diseases in isolation. Inappropriate drug prescription and poor drug compliance are common and contribute to up to 30% of hospital admissions. OPERAM investigators developed STOPP/START criteria ...
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9
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TERMINÉ
Imaging the Force of Cancer (FORCE)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
Cancer is the second leading cause of mortality in EU member states with ~90% of all cancer deaths caused by metastatic spread. Despite its significance, measuring metastatic potential as well as potential indicators of therapy efficacy remain unmet clinical challenges. Recently, it has been demonstrated in vitro, that aggressive metastatic cells pull on their surroundings suggesting that metastat ...
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18
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TERMINÉ
Nanoscale solid-state spin systems in emerging quantum technologies (Spin-NANO)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
...y 14 academic and 7 industrial groups. Network-wide training course in transferable skills will be specially developed and delivered by the Think Ahead (Sheffield), an award winning initiative at the University of Sheffield (award by the Times Higher Education, 2014). Current proposal is designed to advance this multi-disciplinary research field significantly beyond the state-of-the-art, and train ...
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11
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TERMINÉ
Development of a multi-stakeholder dialogue platform and Think tank to promote innovation with Nature based solutions (ThinkNature)
Date du début: 1 déc. 2016, Date de fin: 30 nov. 2019,
Nature-based solutions (NBS) aim to help societies to address a variety of environmental, social and economic challenges in sustainable ways. They are actions which are inspired by and supported by nature. Some involve using and enhancing existing natural solutions to challenges, while others are exploring more novel solutions, for example, based on how non-human organisms and communities cope wit ...
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18
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TERMINÉ
Deciphering PI3K biology in health and disease (Phd)
Date du début: 1 nov. 2015, Date de fin: 31 oct. 2019,
The Phosphoinositide 3-kinase (PI3K) pathway is at the core of multiple fundamental biological processes controlling metabolism, protein synthesis, cell growth, survival, and migration. This inevitably leads to the involvement of the PI3K signalling pathway in a number of different diseases, ranging from inflammation and diabetes to cancer, with PI3K pathway alterations present in almost 80% of hu ...
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11
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TERMINÉ
Principles of Polarity – Integrating genetic, biophysical and computational approaches to understand cell and tissue polarity (PolarNet)
Date du début: 1 oct. 2015, Date de fin: 30 sept. 2019,
The ability of cells to polarize underlies the most basic biological functions such as motility and response to external challenges, but also the formation and maintenance of tissues in a multicellular organism. The importance of cell polarity is underscored by the fact that cell polarity is essential for animal development and is perturbed in disease states such as cancer. Understanding cell pola ...
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9
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TERMINÉ
The Choice for Europe since Maastricht. Member States' Preferences for Economic and Financial Integration (EMU_SCEUS)
Date du début: 1 juil. 2015, Date de fin: 30 juin 2019,
The Eurozone crisis corroborated the warnings of economists that weak economic policy coordination and loose fiscal oversight would be insufficient to stabilise the monetary union. To prevent a recurrence of the crisis, economists, political actors and the “Blueprint” of the European Commission are asking for the construction of a deep and genuine economic and monetary union with reinforced govern ...
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10
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TERMINÉ
Demonstrating synergies in combined natural and engineered processes for water treatment systems (AquaNES)
Date du début: 1 juin 2016, Date de fin: 31 mai 2019,
The AquaNES project will catalyse innovations in water and wastewater treatment processes and management through improved combinations of natural and engineered components. Among the demonstrated solutions are natural treatment processes such as bank filtration (BF), managed aquifer recharge (MAR) and constructed wetlands (CW) plus engineered pre- and post-treatment options. The project focuses on ...
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30
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TERMINÉ
Ultra-low dose of IL-2 for the treatment of recently diagnosed type 1 diabetes (DIABIL-2)
Date du début: 1 oct. 2012, Date de fin: 31 mars 2019,
ConceptThe discovery of regulatory T cells (Tregs) has revolutionized our understanding of autoimmune diseases. As T1D is caused by the failure of Tregs to block autoimmune destruction of pancreatic ß-cells, Treg stimulation has the potential to stop the process, preserve ß-cells’ insulin secretion, and likewise prevent or delay disease progression and improve clinical outcome for patients.Backgro ...
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7
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TERMINÉ
TBVAC2020; Advancing novel and promising TB vaccine candidates from discovery to preclinical and early clinical development (TBVAC2020)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,
The TBVAC2020 proposal builds on the highly successful and long-standing collaborations in subsequent EC-FP5-, FP6- and FP7-funded TB vaccine and biomarker projects, but also brings in a large number of new key partners from excellent laboratories from Europe, USA, Asia, Africa and Australia, many of which are global leaders in the TB field. This was initiated by launching an open call for Express ...
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49
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TERMINÉ
Near-surface Geothermal Resources in the Territory of the Alpine Space (GRETA)
Date du début: 16 déc. 2015, Date de fin: 15 déc. 2018,
Description (EN): The Alpine region must tackle rising energy consumption and, accordingly, CO2 emissions reduction, related mostly to heating needs (mainly from residential and tourism sectors). The potential of renewable energy sources to handle this energy requirement has been discussed in some recent studies. However, the opportunity to utilize Near-Surface Geothermal Energy (NS ...
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12
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TERMINÉ
Accelerated Development of Vaccine benefit-risk Collaboration in Europe (ADVANCE)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,
Aim: The ADVANCE vision is focused on Timely and Best Evidence on Vaccine Effects. Our mission is to establish a best practice framework to rapidly provide robust data on vaccine benefits and risks to support accelerated decision-making.Approach: To achieve this vision through a public-private partnership, ADVANCE partners 1. establish common grounds and rules for collaboration between public and ...
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30
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TERMINÉ
Personalised Prognostic Tools for Early Psychosis Management (PRONIA)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,
Affective and non-affective psychoses have a major negative impact on human society. They account for 6.3% of the global burden of disease and cost €207 billion per year in Europe alone, making them the most expensive brain-related disorders and even more expensive than cardiovascular diseases. This socioeconomic burden is largely caused by two core disease features: onset in adolescence and early ...
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13
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TERMINÉ
Reservoir Computing with Real-time Data for future IT (RECORD-IT)
Date du début: 1 sept. 2015, Date de fin: 31 août 2018,
The aim of this proposal is to develop an intelligent biocompatible sensing device which detects complex behavioural changes in ion concentrations. The sensor will use wet NOMFETs, coated Si nanowires, self-conjugated polymers, arrays of photocells, flow of lipids. The level of ions will be measured by monitoring changes in the response function of the system. The high sensitivity of the device wi ...
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9
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TERMINÉ
Human Brain Project Specific Grant Agreement 1 (HBP SGA1)
Date du début: 1 avr. 2016, Date de fin: 31 mars 2018,
Understanding the human brain is one of the greatest scientific challenges of our time. Such an understanding can provide profound insights into our humanity, leading to fundamentally new computing technologies, and transforming the diagnosis and treatment of brain disorders. Modern ICT brings this prospect within reach. The HBP Flagship Initiative (HBP) thus proposes a unique strategy that uses I ...
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126
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TERMINÉ
Personalized diagnosis and treatment of hyperinsulinemic hypoglycaemia caused by beta-cell pathology (BETACURE)
Date du début: 1 avr. 2014, Date de fin: 31 mars 2018,
Background:Hyperinsulinaemic hypoglycaemia (HH) is a potentially lethal disease caused by over functioning beta cells derived from the pancreatic islets of Langerhans. Lethal HH and brain damage is a problem especially in infants with congenital HH. Current therapeutic approaches are associated with severe side effects/morbidity (diabetes, exocrine pancreas insufficiency etc.) considered acceptabl ...
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17
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TERMINÉ
Graphene-based disruptive technologies (GrapheneCore1)
Date du début: 1 avr. 2016, Date de fin: 31 mars 2018,
This project is the second in the series of EC-financed parts of the Graphene Flagship. The Graphene Flagship is a 10 year research and innovation endeavour with a total project cost of 1,000,000,000 euros, funded jointly by the European Commission and member states and associated countries. The first part of the Flagship was a 30-month Collaborative Project, Coordination and Support Action (CP-CS ...
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158
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TERMINÉ
Negotiating early job-insecurity and labour market exclusion in Europe (NEGOTIATE)
Date du début: 1 mars 2015, Date de fin: 28 févr. 2018,
Through an innovative use of four key concepts (resilience, capability, active agency and negotiation) and primary data (life course interviews, vignette experiments), NEGOTIATE will deliver gender-sensitive comparative knowledge about consequences of early job insecurity. We move beyond the state-of-the-art by investigating the linkages across macro, meso and micro levels as mechanisms of early j ...
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10
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TERMINÉ
Neurobiology and Treatment of Adolescent Female Conduct Disorder: The Central Role of Emotion Processing (FEMNAT-CD)
Date du début: 1 sept. 2013, Date de fin: 28 févr. 2018,
Conduct Disorder (CD) and Oppositional Defiant Disorder with symptoms of Conduct Disorder (which is included among the abbreviation “CD” throughout the proposal) has a highly negative impact for the affected individual as well as for families and society. Although the number of females exhibiting serious aggressive behaviours is growing, the majority of studies on aetiology and treatment of CD hav ...
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19
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TERMINÉ
"MOLECULAR-SCALE ELECTRONICS: Concepts, Contacts and Stability ""MOLESCO""" (MOLESCO)
Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,
"The MOLESCO network will create a unique training and research environment to develop a pool of young researchers capable of achieving breakthroughs aimed at realising the immense potential of molecular electronics. In part this will involve the major challenges of design and fabrication of molecular-scale devices. To deliver this step-change in capability, MOLESCO will coordinate the activities ...
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10
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TERMINÉ
URBan ANthrpogenic heat FLUX from Earth observation Satellites (URBANFLUXES)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2017,
The main goal of the proposed project URBANFLUXES (URBan ANthrpogenic heat FLUX from Earth observation Satellites) is to investigate the potential of Earth Observation (EO) to retrieve anthropogenic heat fluxes. The main research question addresses whether EO is able to provide reliable estimates of anthropogenic heat flux spatiotemporal distribution, at local and city scales. URBANFLUXES will inv ...
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8
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TERMINÉ
Molecular basis of the outer membrane permeability (TRANSLOCATION)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,
Overcoming the barriers that the cell envelope and efflux pumps provide to Gram-negative bacteria is a major bottleneck in the discovery and development of new antibiotics. To respond to this Call we are extending our current network on antibiotic translocation and propose an ambitious project ranging from identification of novel resistance mechanisms in clinical bacterial isolates to crystallizat ...
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28
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TERMINÉ
Cold Molecular Ions at the Quantum Limit (COMIQ)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,
"COMIQ (COld Molecular Ions at the Quantum limit)will investigate how cooling, trapping, and control techniques applied molecular ion can expand the realm of quantum technology, enhance precision meaurements on molecular systems and lead to chemistry at the ultracold quantum limit."
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10
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TERMINÉ
Training scientists to develop and Image materials for Tissue Engineering and Regenerative Medicine (iTERM)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
The iTERM ITN (4 companies, 6 universities) will deliver 12 early stage researchers (ESR) and 1 experienced researcher (ER) trained in imaging, material science, and tissue engineering & regenerative medicine (TERM). For the aging population in the EU donor material is often not available, and artificial tissue needs to be developed to replace and repair damaged tissues. New smart materials have b ...
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8
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TERMINÉ
IMAging GEnetics for MENtal Disorders (IMAGEMEND)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
"Mental disorders are leading causes of disability, absence from work and premature retirement in Europe. While magnetic resonance imaging (MRI) facilities are broadly available and a vast research literature exists, few neuroimaging applications have reached clinical practice in psychiatry. A major problem is that mental illnesses are currently diagnosed as discrete entities defined clinically. I ...
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15
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TERMINÉ
The impact of chromosomal instability on health: Molecular causes and consequences of aneuploidy (PLOIDYNET)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
Aneuploidy, an abnormal number of chromosomes, is a hallmark of cancer cells, affecting the majority of all human tumours. Aneuploidy arises when errors occur during mitosis, as the duplicated chromosomes are distributed between the two new daughter cells. Paradoxically, aneuploidy appears to have detrimental consequences for the physiology of untransformed cells in vitro, inhibiting rather than s ...
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14
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TERMINÉ
Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in EUrope (EU-CERT-ICD)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
An estimated 500.000 sudden cardiac deaths (SCD) occur each year in the European Union. Patients at risk for SCD may benefit from prophylactic treatment with an implantable cardioverter-defibrillator (ICD). ICD implantations have dramatically increased in recent years leading to multi-billion Euros of costs with significant regional disparities across Europe. Information on risks, benefits and cos ...
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27
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TERMINÉ
MOLECULAR BASIS OF ANTIBIOTIC TRANSLOCATION (Translocation)
Date du début: 1 sept. 2013, Date de fin: 31 août 2017,
Multidrug resistant bacteria are now ubiquitous in both hospitals and the larger community. Drug-resistant pathogens are becoming increasingly pervasive, for example, the resurrection of tuberculosis provides one ominous example highlighting the risk associated with evolved drug resistance. Moreover, many pharmaceutical companies abandoned this field and no truly novel active antibacterial compoun ...
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11
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TERMINÉ
DIAmond Devices Enabled Metrology and Sensing (DIADEMS)
Date du début: 1 sept. 2013, Date de fin: 31 août 2017,
The DIADEMS project aims at exploiting the unique physical properties of NV color centres in ultrapure single-crystal CVD-grown diamond to develop innovative devices with unprecedented performances for ICT applications. By exploiting the atom-like structure of the NV that exhibits spin dependent optical transitions, DIADEMS will make optics-based magnetometry possible.The objectives of DIADEMS are ...
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17
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TERMINÉ
Evolutionary dynamics of growth factor production in cancer cell populations (DUNHARROW)
Date du début: 1 sept. 2014, Date de fin: 31 août 2017,
Cancer is a process of clonal selection, and analytical methods from evolutionary biology should be able to explain why cancer tissues are heterogeneous and develop resistance to current therapies. Evolutionary game theory helps understand non-intuitive properties of the frequency-dependent dynamics arising in the cooperative interactions between cancer cells. In particular, the theory of N-person ...
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2
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TERMINÉ
VitaminD3-Omega3-Home Exercise- HeALTHy Ageing and Longevity Trial (DO-HEALTH)
Date du début: 1 janv. 2012, Date de fin: 30 juin 2017,
As the European population is ageing rapidly, the growing number of seniors with age-related chronic diseases poses a challenge on European societies and health care systems. Therapeutic interventions that are effective, affordable and well-tolerated in the prevention of chronic disease are urgently needed and will have an outstanding impact on public health as a whole. Among the most promising in ...
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25
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TERMINÉ
Development of Biomaterial-based Delivery Systems for Ischemic Conditions - An Integrated Pan-European Approach (AngioMatTrain)
Date du début: 1 mai 2013, Date de fin: 30 avr. 2017,
AngioMatTrain focuses on the comprehensive, multidisciplinary understanding of ischemic diseases, from basics to translation, fully supported by 8 full partners (5 universities, 1 hospital and 2 SMEs). This ITN will educate and train 12 Early Stage Researchers and 3 Experienced Researchers scientists in: tissue engineering, materials science, chemistry, functionalisation, cell biology, nanotechnol ...
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8
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TERMINÉ
Indo-European Network in Mathematics for Health and Disease (INDOEUROPEAN-MATHDS)
Date du début: 1 mai 2013, Date de fin: 30 avr. 2017,
"The main aim of this proposal is to set up an Indo-European Research Network in Mathematics for Health and Disease, INDOEUROPEAN-MATHDS, that will allow the transfer of knowledge, research and training between partners. The Network will involve physicists, mathematicians, statisticians, probabilists, biologists, immunologists and engineers. The Network will create new collaborations and reinfor ...
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7
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TERMINÉ
European Autism Interventions - A Multicentre Study for Developing New Medications (EU-AIMS)
Date du début: 1 avr. 2012, Date de fin: 31 mars 2017,
Despite dramatic advances in molecular and imaging technologies, there are currently no effective pharmacological treatments for the core symptoms of autism spectrum disorder (ASD). Major obstructions to this include a lack of aetiologically-driven or pathophysiologically-accurate animal models; an absence of tests that indicate efficacy; and reliance of clinical trials on DSM/ICD10 categories wh ...
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29
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TERMINÉ
Anti-Biopharmaceutical Immunization:Prediction and analysis of clinical relevance to minimize the risk (ABIRISK)
Date du début: 1 mars 2012, Date de fin: 28 févr. 2017,
The ABIRISK project provides an integrated approach to the study of immunization against biopharmaceuticals, bringing together a unique panel of experts from different disciplines. ABIRISK will involve many of the European leaders in rheumatology, gastroenterology, hemophilia and multiple sclerosis, caring for ~30,000 patients treated with biopharmaceuticals, with ~10,000 additional patients recru ...
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39
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TERMINÉ
Decision-making within cells and differentiation entity therapies (DECIDE)
Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,
"Our ITN has both scientific and therapeutic targets. Research in Work Package 1 (WP1) aims to advance understanding of normal blood cell development and why primitive cells fail to differentiate in acute myeloid leukaemia (AML). Research in WP2 will use the information gained from WP1 to develop ways of alleviating the differentiation block in AML and so deliver new agents for use in differentiat ...
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8
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TERMINÉ
Anticorruption Policies Revisited. Global Trends and European Responses to the Challenge of Corruption (ANTICORRP)
Date du début: 1 mars 2012, Date de fin: 28 févr. 2017,
The central objective of ANTICORRP is to investigate and explain the factors that promote or hinder the development of effective anticorruption policies and impartial government institutions. ANTICORRP directly addresses the objective in the Work Program by examining what the causes of corruption are, how corruption can be conceptualized, measured and analysed, what the impact of corruption on s ...
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22
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TERMINÉ
European Modular Education and Training Programme in Safety Sciences for Medicines (SAFESCIMET)
Date du début: 1 janv. 2010, Date de fin: 30 nov. 2016,
Background:In current drug safety education and training in Europe, an integrative and translational approach is lacking. This shortfall has been identified by EUFEPS. The IMI (‘Strategic Research Agenda’), the FDA and the EMEA have also characterised this fact as a crucial gap in the education and training of scientists evaluating the safety of drug candidates and new medicines. Scope and objecti ...
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