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31 projets européens trouvés

Recherche sur 125080 projets européens

 TERMINÉ 

"Clinical and public health research to improve maternal, newborn health and to control sexually transmitted infections" (MNSIRSES)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

"The overall aim of the proposed staff exchange programme is to establish a long lasting collaboration between Moroccan, South African and European research teams involved in clinical epidemiological and public health research. This effort should ultimately lead to improved mother and child health and better control of sexual transmitted diseases. The proposal is therefore structured in seven work ...
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 7

 TERMINÉ 

Non-coding RNAs in neurogenic and neuropathic pain mechanisms and their application for risk assessment, patient stratification and personalised pain medicine (NCRNAPAIN)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

Neuro-immune alterations in the peripheral and central nervous system play a role in the pathophysiology of chronic pain, and non-coding RNAs (ncRNAs) regulate both immune and neuronal processes. Therefore, ncRNAPain proposes that ncRNAs are critically important master switches for chronic pain.ncRNAPain represents a multidisciplinary consortium of clinical partners, molecular and systems-level n ...
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 12

 TERMINÉ 

NEUREN - Neuroscience Research Exchange Network (NEUREN) (NEUREN)

Date du début: 1 sept. 2013, Date de fin: 31 août 2017,

"The NEUREN project is based on an interdisciplinary consortium of 14 laboratories from 4 EU countries (France, Italy, Spain, Poland), 3 industrialized countries (Australia, Canada, USA) and 3 Mediterranean countries (Egypt, Morocco, Lebanon). It covers a large scope of Neuroscience research topics from molecules to integrated physiology, associate basic, translational, and clinical research, from ...
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 6

 TERMINÉ 

Cardiac Origin of Rhythm DISturbances: 3-Dimensional structural investigations (CORDIS3D)

Date du début: 1 avr. 2013, Date de fin: 31 mars 2017,

"Myocardial structure is important in the triggering and maintenance of many cardiac arrhythmias including atrial and ventricular fibrillation. Detailed knowledge of myocardial structure is essential to the understanding of these disorders and in the development of diagnostic and therapeutic strategies. This must include the normal and pathological distribution of key functional proteins such as c ...
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 4

 TERMINÉ 

Combining innovation in vineyard management and genetic diversity for a sustainable European viticulture (INNOVINE)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

"The strategic goal of the project is to help the European vineyard sector facing the increasingly global competition by meeting:* Consumer demands for diversified high quality wines and concerns for food safety* Citizens’ requests for environment-friendly production systems involving decreased or no use of pesticides and spare of not renewable natural resources* Producers’ needs of plant material ...
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 29

 TERMINÉ 

Analysis and classification of mental states of vigilance with evolutionary computation (ACOBSEC)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2016,

Over the last decade, Human-Computer Interaction (HCI) has grown and matured as a field. Gone are the days when only a mouse and keyboard could be used to interact with a computer. The most ambitious of such interfaces are Brain-Computer Interaction (BCI) systems. BCI’s goal is to allow a person to interact with an artificial system using brain activity. A common approach towards BCI is to analyze ...
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 8

 TERMINÉ 

The Human Brain Project (HBP)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the ...
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 116

 TERMINÉ 

European Network of HIV/AIDS Cohort Studies to Coordinate at European and International Level Clinical Research on HIV/AIDS (EuroCoord)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,

Over the past 15 years, EU-funded cohorts and collaborations (EuroSIDA, CASCADE and PENTA), have played a central role in developing our understanding of HIV progression and the effects of ART, enabling European expertise to contribute directly to the advances in patient diagnosis and management worldwide, and providing a continued surveillance mechanism for detection of emerging problems at a Eur ...
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 26

 TERMINÉ 

Developing an efficient e-infrastructure, standards and data-flow for metabolomics and its interface to biomedical and life science e-infrastructures in Europe and world-wide (COSMOS)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2015,

Metabolomics is an important phenotyping technique for molecular biology and medicine. It assesses the molecular state of an organism or collections of organisms through the comprehensive quantitative and qualitative analysis of all small molecules in cells, tissues, and body fluids. Metabolic processes are at the core of physiology. Consequently, metabolomics is ideally suited as a medical tool t ...
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 16

 TERMINÉ 

Multi-strain indigenous Yeast and Bacterial starters for ‘Wild-ferment’ Wine production (WILDWINE)

Date du début: 1 août 2012, Date de fin: 31 juil. 2015,

Traditionally, wines were produced by the resident grape/winery microbiota, whereas nowadays commercial Saccharomyces cerevisiae and Oenococcus oeni starter cultures are widely used to ensure a manageable process. Despite advantages, this may lead to sensory resemblance of wines from diverse origins. Currently, the competitive nature of global wine market urges for the production of premium wines ...
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 17

 TERMINÉ 

Virtual Museum Transnational Network (V-MusT.net)

Date du début: 1 févr. 2011, Date de fin: 31 janv. 2015,

Description The project aims to provide the cultural heritage sector with Virtual Museums that are educational, enjoyable, long-lasting and easy to maintain.Virtual Museums are personalised, immersive, interactive experiences that enhance our understanding of the world around us. The term 'Virtual Museum' is a general one that covers vari ...
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 20

 TERMINÉ 

Systems biology towards novel chronic kidney disease diagnosis and treatment (SysKID)

Date du début: 1 janv. 2010, Date de fin: 31 déc. 2014,

Chronic kidney disease (CKD) affects up to 10% of the population. Besides eventual progression towards end stage renal disease CKD impacts the patient’s quality of life by causing serious comorbidities including cardiovascular complications and bone metabolism disorders. On the everyday clinical level early stage diagnosis and tailored treatment of CKD are still inadequate. In addition, CKD seems ...
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 30

 TERMINÉ 

Pulmonary Imaging Network (Π-NET)

Date du début: 1 nov. 2010, Date de fin: 31 oct. 2014,

The lung is probably one of the most difficult organs to study by MRI because of its low proton density. Still, MRI is very interesting as not exposure of ionizing radiation to patients and its important role for translatability studies. Moreover, assessment of regional pulmonary perfusion and ventilation with clinical value as an indicator of lung function by MRI has been demonstrated using MRI b ...
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 11

 TERMINÉ 

Establishing the role of Purkinje fibres in the development of arrhythmias for the prevention of Sudden Cardiac Death: Insights from a combined in vivo and ex vivo study (PSCD)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2014,

"Sudden cardiac death (SCD) following ventricular fibrillation (VF) is a major cause of mortality in the industrialised world. VF is characterised by chaotic electrical activity in the ventricles leading to severe cardiac dysfunction. Thus far, the underlying mechanisms for the initiation and maintenance of VF are not fully understood. Recent clinical developments in the treatment of VF by the Hos ...
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 2

 TERMINÉ 

Study of Endothelial and Osteoclastic cells cooperation for Bone Tissue Engineering applications (EOBoTE)

Date du début: 1 août 2011, Date de fin: 31 juil. 2014,

Bone diseases like osteoporosis and osteoarthritis are affecting an increasing number of people worldwide. The short- and long-term consequences are an increasing risk of fractures, total joint replacement and bone grafting. Current treatments of osteoporosis are based on inhibition of bone resorption and at best preserve bone volume but do not improve bone formation together with a high risk of c ...
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 2

 TERMINÉ 

Collaborative HIV and Anti-HIV Drug Resistance Network (CHAIN)

Date du début: 1 avr. 2009, Date de fin: 31 mars 2014,

CHAIN is a large scale integrating project aimed to effectively and durably combat new and existing anti-HIV drug resistance in clinical settings, with a special emphasis on Eastern Europe and in heavily affected resource-poor regions in Africa. This will be achieved through our pan-European network of surveillance and basic research activities, the involvement of all main actors in the field of H ...
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 28

 TERMINÉ 

Synapses: from molecules to higher brain function and diseases (SYMBAD)

Date du début: 1 déc. 2009, Date de fin: 28 févr. 2014,

SyMBaD aims to move forward our knowledge on synapse structure and function in the normal and pathological brain. Brain diseases represent a considerable social and economic burden in Europe. Emerging evidence indicates that synaptic dysfunction is associated with a majority of neurological and psychiatric disorders. Novel therapeutical approaches relie on a better knowledge of the synapse and its ...
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 13

 TERMINÉ 

"Role of the lysosomal dysfunction during aging, and implication for Parkinson’s Disease." (AGELYSPARK)

Date du début: 3 déc. 2010, Date de fin: 2 déc. 2013,

"Parkinson’s disease (PD) is a chronic progressive neurodegenerative disorder with no proven neuroprotective or neurorestorative therapy. The most consistent risk factor for developing PD is increasing age. PD is a disease where substantial cell loss in the substantia nigra pars compacta occurs alongside the formation of Lewy Bodies (LB). Although LB represent a pathological hallmark of PD, their ...
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 2

 TERMINÉ 

Arrhythmogenic potential of drugs (ARITMO)

Date du début: 1 janv. 2010, Date de fin: 30 juin 2013,

The ability of some compounds to prolong the QT interval of the electrocardiogram and to precipitate Torsade de Pointes (TdP, a potentially fatal arrhythmia) has caused several regulatory interventions, including drug withdrawals. Specific guidelines have been implemented to detect QT liability of new compounds as early as possible. However there is growing evidence that an increase in the QT inte ...
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 21

 TERMINÉ 

Chemical biology approach to study the role of PDZ domain-mediated interactions in synaptic plasticity (neuroCHEMbiotools)

Date du début: 1 mai 2011, Date de fin: 30 avr. 2013,

Complex dynamic protein-protein interactions are the base of protein-based networks in cells. Among them, the synaptic connection between two neurons is one of the most challenging. The postsynaptic density (PSD) at excitatory synapses in the brain is a prototypical example of protein-based network whose nanoscale structure and composition determines cellular function. Moreover, dynamic regulation ...
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 1

 TERMINÉ 

European Life-science Infrastructure for Biological Information (ELIXIR)

Date du début: 1 nov. 2007, Date de fin: 31 déc. 2012,

"The objective of the ELIXIR preparatory phase is to produce a memorandum or memoranda of understanding between organisations (government agencies, research councils, funding bodies and scientific organisations) within the member states, with the purpose of constructing a world class and globally positioned European infrastructure for the management and integration of information in the life scien ...
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 33

 TERMINÉ 

Image-controlled Ultrasound-induced Drug Delivery (SonoDrugs)

Date du début: 1 nov. 2008, Date de fin: 31 oct. 2012,

The demographic changes in Europe towards an aging society will coincide with increasing morbidity of the population. European citizens need improved access to state-of-the-art medical care especially in oncology and cardiology, while keeping expenditures on healthcare affordable. New therapeutic options such as externally triggered local drug release at the diseased area hold promise to solve urg ...
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 18

 TERMINÉ 

Integration of Novel Nanoparticle based Technology for Therapeutics and Diagnosis of different types of Cancer (NANOTHER)

Date du début: 1 sept. 2008, Date de fin: 31 août 2012,

The breakthrough objective of NANOTHER is to develop & characterise a novel nanoparticle system that will be used as a therapeutic agent or diagnosis tool for breast cancer, colorectal cancer & bone metastasis. Theranostics, the development of nanoparticles with both functionalities, will also be carried out using the hyperthermic effect to kill tumour cells or to release the selected drug . The n ...
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 19

 TERMINÉ 

Safety Of non-Steroidal anti-inflammatory drugs (SOS)

Date du début: 1 nov. 2008, Date de fin: 30 avr. 2012,

"The Safety Of non-Steroidal anti-inflammatory drugs (SOS) proposal aims to assess the relative cardiovascular (CVD) and gastrointestinal (GI) safety of non-steroidal anti-inflammatory drugs (NSAIDs). The NSAIDs are divided in traditional NSAIDs (tNSAIDs) and the newer COX-II inhibitors(coxibs). The aim will be fulfilled by a two-phase approach comprising systematic reviews and synthesis of CVD an ...
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 11

 TERMINÉ 

Role of lateral diffusion of AMPA Receptors in LTP (TRAPAMPAR)

Date du début: 1 mars 2010, Date de fin: 29 févr. 2012,

Synaptic recruitment of AMPA receptors (AMPAR) is a critical step in synaptic plasticity events such as Long term potentiation (LTP). Although the signaling events necessary for the induction of LTP are well known (i.e. NMDA receptor activation and activation of protein kinase cascades), the source of the newly inserted AMPAR is still unclear. There are two pools of AMPA receptors that can be pote ...
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 1

 TERMINÉ 

Exploring and understanding adverse drug reactions by integrative mining of clinical records and biomedical knowledge (EU-ADR)

Date du début: 1 févr. 2008, Date de fin: 31 janv. 2012,

Serious adverse effects resulting from the treatment with thalidomide prompted modern drug legislation more than 40 years ago. Post-marketing spontaneous reporting systems for suspected adverse drug reactions (ADRs) have been a cornerstone to detect safety signals in pharmacovigilance. It has become evident that adverse effects of drugs may be detected too late, when millions of persons have alrea ...
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 15

 TERMINÉ 

Priming for L-dopa-induced dyskinesia and neurotransmitter receptor trafficking dysregulation in parkinsonism (PrimLID)

Date du début: 1 juin 2010, Date de fin: 31 août 2011,

L-dopa-induced dyskinesia (LID) severely limits the usability of L-dopa in Parkinson’s disease (PD) patients and a treatment is needed to improve their quality of life. The project aims at elucidating the “priming” phenomenon in PD, i.e. the unchangeable modification of brain response to dopamine (DA), that leads to the development of LID. We will investigate the role of neurotransmitter receptor ...
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 1

 TERMINÉ 

SYNAPTIC TRAFFICKING OF KAINATE RECEPTORS IN HIPPOCAMPAL CA3 PYRAMIDAL CELLS IN VIVO (KARTRAF)

Date du début: 1 mai 2009, Date de fin: 30 avr. 2011,

"The proper function of neurotransmitters receptors is highly dependent on their precise subcellular localization in neurons. The molecular and cellular mechanisms that govern the synaptic localization of glutamate receptors both depend on the molecular structure of receptors and on interactions with cytoplasmic and extracellular proteins. These mechanisms have been widely studied using a variety ...
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 1

 TERMINÉ 

Ethnic Differences in Education and Diverging Prospects for Urban Youth in an Enlarged Europe (EDUMIGROM)

Date du début: 1 mars 2008, Date de fin: 28 févr. 2011,

The research project aims to study how ethnic differences in education contribute to the diverging prospects for minority ethnic youth and their peers in urban settings. Through a comparative endeavor involving nine countries from among old and new member states of the European Union, EDUMIGROM will explore how far existing educational policies, practices and experiences in markedly different welf ...
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 11

 TERMINÉ 

Controlling Biogenic Amines in Traditional Food Fermentations in Regional Europe (BIAMFOOD)

Date du début: 1 févr. 2008, Date de fin: 31 janv. 2011,

"Food fermentations are among the traditional industries that have a long standing history worldwide. In spite of great technological advantages, much of the industry is still based on traditional, experienced-based techniques that are strongly rooted in specific geographic regions. In food fermentations, consortia of microorganisms are essential to the process, and determine the characteristics o ...
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 15

 TERMINÉ 

Medical Education in Europe 2

Date du début: 1 oct. 2009,

The MEDINE2 Thematic Network in Medical Education in Europe will build on the work of the MEDINE Network 2004-2007. The Networks is requiered because the education and training of medical doctors to high standard is critical to the physical health, well-being, productivity and social cohesion of European society. Variours issues must be addressed. Despite facilitative legislation, mobility of med ...
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 89