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Plus de 40 projets européens trouvés

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 TERMINÉ 

European HIV Vaccine Alliance (EHVA): a EU platform for the discovery and evaluation of novel prophylactic and therapeutic vaccine candidates (EHVA)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Many HIV vaccine concepts and several efficacy trials have been conducted in the prophylactic and therapeutic fields with limited success. There is an urgent need to develop better vaccines and tools predictive of immunogenicity and of correlates of protection at early stage of vaccine development to mitigate the risks of failure. To address these complex and challenging scientific issues, the Eur ...
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 43

 TERMINÉ 

European AIDS Vaccine Initiative 2020 (EAVI2020)

Date du début: 1 nov. 2015, Date de fin: 31 oct. 2020,

HIV-1 is responsible for a global pandemic of 35 million people, and continues to spread at a rate of >2 million new infections/year. It is widely acknowledged that a protective vaccine would be the most effective means to reduce HIV-1 spread and ultimately eliminate the pandemic, while a therapeutic vaccine may help mitigate the clinical course of disease and lead to strategies of viral eradicati ...
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 27

 TERMINÉ 

Combatting Bacterial Resistance in Europe (COMBACTE-NET)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2019,

The emergence of Antibiotic-resistant bacteria (ARB) is a global problem, having recently been elevated to the top three threats identified by the World Health Organisation (WHO), and subject of numerous national and international government activities, including the Trans-Atlantic Task Force on Antimicrobial Resistance established by the US and EU presidencies. The estimated costs of ARB are aro ...
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 38

 TERMINÉ 

Innovative controls for renewable sources Integration into smart energy systems (INCITE)

Date du début: 1 déc. 2015, Date de fin: 30 nov. 2019,

The continuous increase of the share of renewable energy sources is redefining the electrical networks. In future infrastructures, an important number of agents (sources, storage devices and consumers) will have intelligent interfaces allowing the regulation of the injection and extraction of power into the grid. This context will create multiple alternatives to increase the efficiency in electric ...
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 9

 TERMINÉ 

Open Digital Research Environment Toolkit for the Advancement of Mathematics (OpenDreamKit)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

OpenDreamKit will deliver a flexible toolkit enabling research groups to set up Virtual Research Environments, customised to meet the varied needs of research projects in pure mathematics and applications and supporting the full research life-cycle from exploration, through proof and publication, to archival and sharing of data and code.OpenDreamKit will be built out of a sustainable ecosystem of ...
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 17

 TERMINÉ 

BIOactive implantable CApsule for PANcreatic islets immunosuppression free therapy (BIOCAPAN)

Date du début: 1 juin 2015, Date de fin: 31 mai 2019,

The key therapeutic issue in diabetes mellitus type I and II is glycaemic control. Reductions of constant self-control, of insulin injections, and of long-term complications would have tremendous benefit for quality of life. The best therapy option is the transplantation of allogeneic islet cells, but the current state of the art limits the applicability of this approach. Implanting unprotected gr ...
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 10

 TERMINÉ 

Development of Selective Carbohydrate Immunomodulators Targeting C-type Lectin Receptors on Antigen Presenting Cells (IMMUNOSHAPE)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

IMMUNOSHAPE aims at training a new generation of scientists that will be capable of combining state of the art synthesis and screening technology to develop new lead structures for highly selective glycan based multivalent immunotherapeutics for the treatment of cancer, autoimmune diseases and allergy. To this end, we have set up a training program in a unique academic-industrial environment that ...
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 17

 TERMINÉ 

Critical State Soil Mechanics Revisited: Fabric Effects (SOMEF)

Date du début: 1 mars 2012, Date de fin: 28 févr. 2018,

The theory of Critical State Soil Mechanics (CSSM) has become a paradigm within the framework of which elastoplastic soil constitutive models have been developed for the last 50 years. The present project will constructively challenge this paradigm from a missing fundamental perspective, namely the effect of soil fabric on the premises of CSSM.The current CSSM postulates that at critical state the ...
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 4

 TERMINÉ 

Mineral Intelligence Capacity Analysis (MICA)

Date du début: 1 déc. 2015, Date de fin: 31 janv. 2018,

Primary and secondary raw materials are fundamental to Europe’s economy and growth. They represent the most important link in the value chain of industrial goods production, which plays a prominent role as a source of prosperity in Europe. However, as stated in the call, there exists to-date no raw materials knowledge infrastructure at EU level. The Mineral Intelligence Capacity Analysis (MICA) p ...
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 17

 TERMINÉ 

Investigating Tectonism-Erosion-Climate-Couplings (ITECC)

Date du début: 1 janv. 2013, Date de fin: 30 juin 2017,

Tectonics and climate are interdependent. The tectonics of orogens are moderated by climate through erosion. Exposure of rock by tectonics or erosion is critical to the feedback which governs changes in global climate, whilst topography influences rainfall. The principle objective of iTECC is to use the Himalaya as a natural laboratory to train young scientists in understanding such coupled proces ...
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 11

 TERMINÉ 

Arrowhead (ARROWHEAD)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,

"Our society is facing both energy and competitiveness challenges. These challenges are tightly linked and require new dynamic interactions between energy producers and energy consumers, between machines, between systems, between people and systems, etc. Cooperative automation is the key for these dynamic interactions and is enabled by the technology developed around the Internet of Things and Ser ...
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 87

 TERMINÉ 

Scalable ProactivE Event-Driven Decision making (SPEEDD)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2017,

SPEEDD (Scalable ProactivE Event-Driven Decision making) will develop a system for proactive event-based decision-making: decisions will be triggered by forecasting events -whether they correspond to problems or opportunities- instead of reacting to them once they happen. The decisions and actions will be real-time, in the sense that they will be taken under tight time constraints, and require on- ...
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 10

 TERMINÉ 

Flow in Transforming Porous Media (FlowTrans)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

The FlowTrans Initial Training Network is a unique environment for career development, built on joint challenges of Industry and University partners in a newly emerging supra-disciplinary field, spanning from Physics to Earth Sciences and aiming to understand Flow in Transforming Porous Media. Training will be hosted by 8 Universities in synergy with 2 full and 4 associated industry partners with ...
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 10

 TERMINÉ 

Assess Inquiry in Science, Technology and Mathematics Education (ASSIST-ME)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

ASSIST-ME is a high level research project with a societal impact that will investigate formative and summative assessment methods to support and to improve inquiry-based approaches in European science, technology and mathematics (STM) education. Based on an analysis of what is known about summative and formative assessment of knowledge, skills and attitudes related to key STM competences and an a ...
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 11

 TERMINÉ 

NOX enzymes as mediators of inflammation-triggered neurodegeneration: modulating NOX enzymes as novel therapies (NEURINOX)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,

NEURINOX aims at elucidating the role of NADPH oxidases (NOX) in neuroinflammation and its progression to neurodegenerative diseases (ND), as well as evaluating the potential of novel ND therapeutics approaches targeting NOX activity. NOX generate reactive oxygen species (ROS) and have emerged as regulators of neuroinflammation. Their role is complex: ROS generated by NOX lead to tissue damage in ...
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 15

 TERMINÉ 

Evolution of Evolution (EvoEvo)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2016,

Evolution is the major source of complexity on Earth, at the origin of all the species we can observe, interact with or breed. On a smaller scale, evolution is at the heart of the adaptation process for many species, in particular micro-organisms (e.g. bacteria, viruses...). Microbial evolution results in the emergence of the species itself, and it also contributes to the organisms' adaptation to ...
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 7

 TERMINÉ 

Compound Semiconductors for 3D integration (COMPOSE3)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2016,

COMPOSE3 aims to develop 3D stacked circuits in the front end of line of Complementary Metal Oxide Semiconductor (CMOS) technology, based on high mobility channel materials. The final objective is a 3D stacked SRAM cell, designed with gates length taken from the 14nm technology node. This technology will provide a new paradigm shift in density scaling combined with a dramatic increase in the power ...
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 10

 TERMINÉ 

Harmonized approach to stress tests for critical infrastructures against natural hazards (STREST)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

Critical Infrastructures (CIs) provide essential goods and services for modern society; they are highly integrated and have growing mutual dependencies. Recent natural events have shown that cascading failures of CIs have the potential for multi-infrastructure collapse and widespread societal and economic consequences.Moving toward a safer and more resilient society requires improved and standardi ...
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 13

 TERMINÉ 

Architecture for Multi-criticality Agile Dependable Evolutionary Open System-of-Systems (AMADEOS)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

Description The objective of this research proposal is to bring time awareness and evolution into the design of System-of-Systems (SoS), to establish a sound conceptual model, a generic architectural framework and a design methodology including tools for prototyping, for the modeling, development and evolution of time-sensitive SoSes with po ...
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 7

 TERMINÉ 

Mont-Blanc 2, European scalable and power efficient HPC platform based on\nlow-power embedded technology (Mont-Blanc 2)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

The Mont-Blanc project aims to develop a European Exascale approach leveraging on commodity power-efficient embedded technologies. The project has developed a HPC system software stack on ARM, and will deploy the first integrated ARM-based HPC prototype by 2014, and is also working on a set of 11 scientific applications to be ported and tuned to the prototype system.The rapid progress of Mont-Blan ...
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 17

 TERMINÉ 

The Human Brain Project (HBP)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the ...
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 116

 TERMINÉ 

Integrated Solutions for Agile Manufacturing in High-mix Semiconductor Fabs (INTEGRATE)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2015,

European IC manufacturers are on the way to become suppliers of customized products for OEM companies, which means high flexibility and product diversity. The project aims at conducting research to support the development of new manufacturing procedures, new organizations and new information and control tools to enable IC production lines to efficiently manage a high product and technology mix and ...
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 29

 TERMINÉ 

Information, Fluctuations, and Energy Control in Small Systems (INFERNOS)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2015,

Strong statistical fluctuations in meso- and nano-scale structures make their thermodynamic properties extremely dependent on the information available about them. The most basic process illustrating the importance of information to statistical systems is the information-to-energy conversion in the famous Maxwell's Demon (MD). Our primary goal is to study both experimentally and theoretically the ...
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 9

 TERMINÉ 

Changing Permafrost in the Arctic and its Global Effects in the 21st Century (PAGE21)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,

Permafrost is defined as ground that remains continuously at or below 0°C for at least two consecutive years; some 24% of the land surface in the northern Hemisphere is classified as permafrost. In the Northern high latitudes, strong warming has been observed over the recent decades, and climate models project strong future warming. A projected decline in the extent of permafrost will have a major ...
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 20

 TERMINÉ 

Distributed MILS for Dependable Information and Communication Infrastructures (D-MILS)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2015,

Modern critical systems bear great responsibilities and face escalating challenges. Distributed systems for critical applications are costly and time-consuming to develop and to certify. Since there is little automated support for early assurance that a system faithfully implements its architectural design and satisfies its requirements, qualification testing and certification processes often reve ...
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 11

 TERMINÉ 

HEMatopoietic cell IDentity : genetic and epigenetic regulation in normal and malignant hematopoiesis (HEM_ID)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,

In hematopoiesis, failure to maintain homeostasis and regenerative functions result in a multitude of hematological malignancies, including myelodysplastic syndromes, lymphomas and leukemias, that represent a medical challenge and a large socioeconomic burden because of the large number of affected patients of all age groups. Although hierarchical organization of the hematopoietic system has been ...
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 12

 TERMINÉ 

Global Mercury Observation System (GMOS)

Date du début: 1 nov. 2010, Date de fin: 31 oct. 2015,

The overall goal of the proposed project is to develop a coordinated global observation system for mercury able to provide temporal and spatial distributions of mercury concentrations in ambient air and precipitation over land and over surface waters at different altitudes and latitudes around the world. This will then provide high quality data for the validation and application of regional and g ...
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 25

 TERMINÉ 

Virtual Earthquake and seismology Research Community in Europe e-science environment (VERCE)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2015,

The earthquake and seismology research, an intrinsically Global undertaking, addresses both fundamental problems in understanding Earth's internal wave sources and structures, and augment applications to societal concerns about natural hazards, energy resources, environmental change, and national security. This community is central in the European Plate Observing System (EPOS), the ESFRI initiativ ...
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 12

 TERMINÉ 

Towards continuous monitoring of the continuously changing Earth (Whisper)

Date du début: 1 juil. 2009, Date de fin: 30 juin 2015,

This project is focused on the use of the seismic ambient noise to monitor slight changes of properties in the solid Earth. Processing of noise records allow s to mimic a situation in which a perfectly repeatable source is activated at the location of a passive recorder. The implication is the detection of changes of strain at depth with applications in different contexts. A major field of applic ...
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 2

 TERMINÉ 

Mont-Blanc, European scalable and power efficient HPC platform based on low-power embedded technology (Mont-Blanc)

Date du début: 1 oct. 2011, Date de fin: 30 juin 2015,

There is a continued need for higher compute performance: scientific grand challenges, engineering, geophysics, bioinformatics, etc. However, energy is increasingly becoming one of the most expensive resources and the dominant cost item for running a large supercomputing facility. In fact the total energy cost of a few years of operation can almost equal the cost of the hardware infrastructure. En ...
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 14

 TERMINÉ 

Autonomic Service-Component Ensembles (ASCENS)

Date du début: 1 oct. 2010, Date de fin: 31 mars 2015,

Description Future software-intensive systems, such as sensor networks, power grids, satellite and robot swarms, will generally exhibit a number of characteristic features:Massive numbers of nodes, nodes with complex behavior, or complex interactions between nodes.Operation in open and non-deterministic environments with variable network top ...
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 17

 TERMINÉ 

Quantum Nano-Electronics Training (Q-NET)

Date du début: 1 avr. 2011, Date de fin: 31 mars 2015,

Q-NET will provide initial training in the general field of Quantum Nano-Electronics, in particular spintronics, molecular electronics, single-electronics, quantum dots and nanowires, nano-cooling. The recruited researchers will be trained to state-of-the-art technologies of nanofabrication, near-field microscopies, transport measurement under extreme conditions (low temperatures, magnetic field, ...
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 8

 TERMINÉ 

Cyber-Physical European Roadmap and Strategy (CyPhERS)

Date du début: 1 juil. 2013, Date de fin: 28 févr. 2015,

The ongoing integration of software-intensive embedded systems and global communication networks into Cyber-Physical Systems (CPS) is considered to be the next revolution in ICT with a lot of game-changing business potential and novel business models for integrated services and products. CPS will be a core enabling technology for securing economic leadership in embedded systems/ICT, having an enor ...
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 6

 TERMINÉ 

Pan-European Gas-AeroSol-climate interaction Study (PEGASOS)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2014,

The Pan-European Gas-AeroSOls-climate interaction Study (PEGASOS) European large scale integrating project brings together most of the leading European research groups, with state-of the-art observational and modeling facilities to:(1) Quantify the magnitude of regional to global feedbacks between atmospheric chemistry and a changing climate and to reduce the corresponding uncertainty of the major ...
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 27

 TERMINÉ 

Highly-complex and networked control systems (HYCON2)

Date du début: 1 sept. 2010, Date de fin: 30 nov. 2014,

ICT developments both enable and also enforce large-scale, highly-connected systems in society and industry. Knowledge to cope with these emerging systems is lacking. HYCON2 will stimulate and establish the long-term integration of the European research community, leading institutions and industry in the strategic field of control of complex, large-scale, and networked dynamical systems. It will i ...
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 30

 TERMINÉ 

CErtification of Real Time Applications desIgNed for mixed criticaliTY (CERTAINTY)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2014,

Pushed by economical and ecological stakes, embedded systems from the avionics, automotive and automation domains, featuring real-time, safety and critical capabilities have to face increasing performance needs that will no more be satisfied by existing architectures based on single-cores. Current trends are to take benefit from multi-core processors high performance in replacing single-cores by m ...
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 9

 TERMINÉ 

Systems prediction of Chronic Lung Allograft Dysfunction (SysCLAD)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2014,

Lung transplantation (LT) is the standard of care for selected patients with chronic respiratory failure. Chronic lung allograft dysfunction (CLAD) (i.e. “Bronchiolitis obliterans syndrome” (BOS) and “Restrictive Allograft Syndrome” (RAS)) represents a major health risk for LT recipients, requiring the use of heavy treatments and possible retransplantation. Observed in almost 50% of patients afte ...
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 9

 TERMINÉ 

A challenge on large-scale biomedical semantic indexing and question answering (BioASQ)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2014,

BioASQ will push for a solution to the information access problem of biomedical experts by setting up a challenge on biomedical semantic indexing and question answering (QA). Biomedical knowledge is dispersed in hundreds of heterogeneous knowledge sources and databases; many of them are connected on the Linked Open Data cloud. Biomedical experts, on the other hand, are in constant need of highly s ...
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 8

 TERMINÉ 

CALIPSO: Connect All IP-based Smart Objects! (CALIPSO)

Date du début: 1 sept. 2011, Date de fin: 31 août 2014,

Smart Objects and the Internet of Things provide unparalleled means toconnect the physical world with the digital world, enabling importantapplications such as Smart Infrastructures, Smart Cities, and SmartToys. But existing systems are typically proprietary and tailored toone specific application and sacrifice interoperability for low powerconsumption. This hinders widespread adoption.CALIPSO bu ...
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 9

 TERMINÉ 

Determining (epi)genetic therapeutic signatures for improving lung cancer prognosis (CURELUNG)

Date du début: 1 janv. 2011, Date de fin: 30 juin 2014,

"Lung cancer (LC) is still the most lethal type of cancer worldwide. The extremely poor prognosis for LC patients is partly due to the lack of effective therapies. At present, most patients with pulmonary carcinomas are treated with chemotherapy. This essentially consists of classic cytotoxic drugs which only improve survival in small cohorts in few cases. In spite of the rapidly growing understan ...
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 11