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 TERMINÉ 

A Systems medicine approach to chronic inflammatory disease (SYSCID)

Date du début: 1 janv. 2017, Date de fin: 31 mars 2022,

"The SYSCID consortium aims to develop a systems medicine approach for disease prediction in CID. We will focus on three major CID indications with distinct characteristics, yet a large overlap of their molecular risk map: inflammatory bowel disease, systemic lupus erythematodes and rheumatoid arthritis. We have joined 15 partners from major cohorts and initiatives in Europe (e.g.IHEC, ICGC, Twins ...
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 16

 TERMINÉ 

Healthy minds from 0-100 years: Optimising the use of European brain imaging cohorts (Lifebrain)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Our main objective is to identify determinants of brain, cognitive and mental health at different stages of life. By integration, harmonisation and enrichment of major European neuroimaging studies of age differences and changes, we will obtain an unparalleled database of fine-grained brain, cognitive and mental health measures of more than 6.000 individuals. Longitudinal brain imaging, genetic an ...
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 16

 TERMINÉ 

Spectral Statistics of Structured Random Matrices (RandMat)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

The purpose of this proposal is a better mathematical understanding of certain classes of large random matrices. Up to very recently, random matrix theory has been mainly focused on mean-field models with independent entries. In this proposal I instead consider random matrices that incorporate some nontrivial structure. I focus on two types of structured random matrices that arise naturally in imp ...
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 1

 TERMINÉ 

Combatting Bacterial Resistance in Europe - Molecules against Gram Negative Infections (COMBACTE-MAGNET)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2021,

Antimicrobial resistance (AMR) is a major global public health threat, and most troublesome is the rapid emergence and dissemination of multidrug resistant (MDR) Enterobacteriaceae, Acinetobacter species and Pseudomonas aeruginosa. There is an unmet medical need to prevent P. aeruginosa infection in critically ill patients and to develop new antibiotics for infections caused by Gram-negative bacte ...
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 44

 TERMINÉ 

Unravelling the architecture and the cartography of the human centriole (ACCENT)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

The centriole is the largest evolutionary conserved macromolecular structure responsible for building centrosomes and cilia or flagella in many eukaryotes. Centrioles are critical for the proper execution of important biological processes ranging from cell division to cell signaling. Moreover, centriolar defects have been associated to several human pathologies including ciliopathies and cancer. T ...
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 1

 TERMINÉ 

High-density cortical implants for cognitive neuroscience and rehabilitation of speech using brain-computer interfaces. (BrainCom)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2021,

The goal of BrainCom is to develop a new generation of neuroprosthetic devices for large-scale and high density recording and stimulation of the human cortex, suitable to explore and repair high-level cognitive functions. Since one of the most invalidating neurospychological conditions is arguably the impossibility to communicate with others, BrainCom primarily focuses on the restoration of speech ...
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 10

 TERMINÉ 

Molecular Basis of Toxoplasma gondii Encystation and Persistence (ToxoPersist)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2021,

Toxoplasma gondii is the most successful obligate intracellular parasites infecting virtually all warm-blooded animals. A infection initiates with the dissemination of the fast-replicating tachyzoites. At the onset of the immune response tachyzoites convert into slow-growing bradyzoites that form cysts in the central nervous system and in striated and heart muscles. Encystation ensures life-long p ...
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 1

 TERMINÉ 

Forecasting the recurrence rate of volcanic eruptions (FEVER)

Date du début: 1 avr. 2016, Date de fin: 31 mars 2021,

Volcanic eruptions occur with a frequency that is inversely proportional to their magnitude. Datasets of natural volcanic events, currently used to determine the recurrence rate of volcanic eruptions are intrinsically biased. Combining physical modelling of processes with detailed statistical analysis has been demonstrated essential for assessing reliably the recurrence rate of natural hazards, su ...
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 1

 TERMINÉ 

The European network for observing our changing planet (ERA-PLANET)

Date du début: 1 févr. 2016, Date de fin: 31 janv. 2021,

In the last decade a significant number of projects and programmes in different domains of environmental monitoring and Earth observation have generated a substantial amount of data and knowledge on different aspects related to environmental quality and sustainability. Big data generated by in-situ or satellite platforms are being collected and archived with a plethora of systems and instruments m ...
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 38

 TERMINÉ 

Laser Lightning Rod (LLR)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Controlling lightning is a long time dream of mankind. The goal of the present project is to investigate and develop a new type of lightning protection based on the use of upward lightning discharges initiated through a high repetition rate multi terawatt laser. The feasibility of the novel technique and the project’s prospect of success are based on recent research providing new insights into the ...
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 9

 TERMINÉ 

Investigating the impact of meditation training on mental health and wellbeing in the ageing population (MEDIT-AGEING)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

As the number of older people in Europe grows, increasing healthy life years is a priority. Cognitive decline, dementia (e.g. Alzheimer’s disease, AD), sleep disturbances and depression, all related to psychological distress and anxiety, are significant drivers of reduced quality of life in older adults. This project builds on evidence that lifestyle factors and meditation practice have the potent ...
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 12

 TERMINÉ 

Management of Climatic Extreme Events in Lakes Reservoirs for the Protection of Ecosystem Services (MANTEL)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Environmental perturbations to lakes and reservoirs occur largely as episodic climatic events. These range from relatively short mixing events to storms and heat waves. While the driving events occur along a continuum of frequency and magnitude, however, their effect is generally longer lasting than the events themselves. In addition, the more extreme weather events are now becoming increasingly ...
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 8

 TERMINÉ 

Common mechanisms and pathways in Stroke and Alzheimer's disease. (CoSTREAM)

Date du début: 1 déc. 2015, Date de fin: 30 nov. 2020,

Common mechanisms and pathways in Stroke and Alzheimer's disease.It has long been recognized that stroke and (Alzheimer’s Disease) AD often co-occur and have an overlapping pathogenesis. As such, these two diseases are not considered fellow travelers, but rather partners in crime. This multidisciplinary consortium includes epidemiologists, geneticists, radiologists, neurologists with a longstandin ...
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 11

 TERMINÉ 

Quantum Communications for ALL (QCALL)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2020,

Quantum Communications for ALL (QCALL) endeavors to take the next necessary steps to bring the developing quantum technologies closer to the doorsteps of end users. Quantum communications (QC) is well-known for its offering ultra-secure cryptographic key-exchange schemes—resilient to any future technological advancement. QCALL will empower a nucleus of researchers in this area to provide secure co ...
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 8

 TERMINÉ 

Regulation of mitochondrial expression (REMIX)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2020,

Mitochondria are essential organelles found in every eukaryotic cell, required to convert food into usable energy. The mitochondrial oxidative phosphorylation (OXPHOS) system, which produces the majority of cellular energy in the form of ATP, is controlled by two distinct genomes: the nuclear and the mitochondrial genome (mtDNA). Mutations in mitochondrial genes encoded by either genome could caus ...
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 9

 TERMINÉ 

Targeting SYNthetic lethal interactions for new cancer treatments TRAINing network (SYNTRAIN)

Date du début: 1 sept. 2016, Date de fin: 31 août 2020,

Breast and ovarian cancer constitute serious health challenges in the EU. To identify new improved cancer therapeutic approaches, we will pursue a multi-facetted synthetic lethal approach, which takes advantage of the inherent genetic instability of cancer cells. Most mutations acquired by cancer cells do not cause lethality, but the very same mutations may cause cell death when a second gene in a ...
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 10

 TERMINÉ 

PLAtform for Climate Adaptation and Risk reDuction (PLACARD)

Date du début: 1 juin 2015, Date de fin: 31 mai 2020,

Significant challenges exist towards strengthening the Climate Change Adaptation (CCA) and Disaster Risk Reduction (DRR) communities for coherent, mutually reinforcing and pragmatic planning and action. PLACARD seeks to support the coordination of these two communities. PLACARD will tackle current challenges by 1) providing a common ‘space’ where CCA and DRR communities can come together, share ex ...
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 10

 TERMINÉ 

Optimized drug combinations for effective cancer treatment: a personalised approach. (OPTIM)

Date du début: 1 mai 2016, Date de fin: 30 avr. 2020,

This project aims to improve the treatment of metastasized colorectal carcinoma (mCRC), as treatment options after first line chemotherapy are desperately needed. The key to improvement of cancer therapy resides in optimal combination of drugs. Optimally combining drugs is non-trivial due to the large number of possibilities, especially when more than two drugs are combined at various doses. In th ...
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 1

 TERMINÉ 

Combatting Bacterial Resistance in Europe - Carbapenem Resistance (COMBACTE-CARE)

Date du début: 1 mars 2015, Date de fin: 28 févr. 2020,

Multi-drug resistant Gram-negative bacteria (MDR-GNB): the ultimate challenge!Antibiotic resistance is a global public health concern recently elevated to the top three threats identified by the WHO, and subject of numerous national and international government activities. Although focused strategies have beneficially influenced infection rates due to methicillin resistant Staphylococcus aureus (M ...
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 23

 TERMINÉ 

Geospatial based Environment for Optimisation Systems Addressing Fire Emergencies (GEO-SAFE)

Date du début: 1 févr. 2016, Date de fin: 31 janv. 2020,

In EU and Australia, every year thousands of square miles of forests and other lands burn due to wildfires. These fires cause important economic and ecological losses, and often, human casualties. Both EU and Australian governments are aware of how crucial it is to improve wildfires’ management and containment. Scientists from different specialties, both in EU and Australia, have already developed ...
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 10

 TERMINÉ 

Methodologies and Data mining techniques for the analysis of Big Data based on Longitudinal Population and Epidemiological Registers (LONGPOP)

Date du début: 1 févr. 2016, Date de fin: 31 janv. 2020,

European societies face rapid social changes, challenges and benefits, which can be studied with traditional tools of analysis, but with serious limitations. This rapid transformation covers changes in family forms, fertility, the decline of mortality and increase of longevity, and periods of economic and social instability. Owing to population ageing across Europe, countries are now the experienc ...
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 10

 TERMINÉ 

Reinventing Democracy in Europe: Youth Doing Politics in Times of Increasing Inequalities (EURYKA)

Date du début: 1 févr. 2017, Date de fin: 31 janv. 2020,

The proposed project aims to study the relations between inequalities and young people's ways of doing politics as well as to advance scenarios for future democratic models and political systems in Europe that are more inclusive for young people. It has three main objectives: (1) To provide systematic evidence on the ways in which inequalities are lived by young people and (re)acted upon, explorin ...
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 10

 TERMINÉ 

Advanced European Network of E-infrastructuresfor Astronomy with the SKA (AENEAS)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,

The objective of the AENEAS project is to develop a concept and design for a distributed, federated European Science Data Centre (ESDC) to support the astronomical community in achieving the scientific goals of the Square Kilometre Array (SKA). The scientific potential of the SKA radio telescope is unprecedented and represents one of the highest priorities for the international scientific communit ...
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 31

 TERMINÉ 

European Prevention of Alzheimer’s Dementia Consortium (EPAD)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,

Background:The secondary prevention of Alzheimer’s dementia (AD) is achievable if we can identify individuals at risk of disease progression defined by biomarker evidence of AD pathology and no or only minimal clinical symptoms and engage them in a standing adaptive clinical trial, of the highest quality, testing multiple interventions. To achieve this, EPAD will also provide the analytical infras ...
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 40

 TERMINÉ 

Smart Sensor Technologies and Training for Radiation Enhanced Applications andMeasurements (STREAM)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

STREAM is a 4-year multi-site training network that aims at career development of Early Stage Researchers (ESRs) on scientific design, construction manufacturing and of advanced radiation instrumentation. STREAM targets the development of innovative radiation-hard, smart CMOS sensor technologies for scientific and industrial applications. The platform technology developed within the project will b ...
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 11

 TERMINÉ 

Development of Novel Statistical Tools for the Analysis of Astronomical Data (ASTROSTAT)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

We propose an interdisciplinary collaboration network involving leading groups in Astrophysics (Astrophysics Group in Crete, Geneva Observatory, Smithsonian Astrophysical Observatory, Ohio State University. and Nortwestern University), and Statistics (Imperial College, University. of California Davis). The goal of this project is to share expertise between the different fields and geographical ar ...
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 4

 TERMINÉ 

Emerging population issues in sub-Saharan Africa: Cross-checking and promoting demographic data for better action (DEMOSTAF)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

DEMOSTAF (DEMOgraphy-STatistics-for-Africa) brings together European and African research institutes as well as non academic African national statistics offices (NSOs) in a staff exchange programme, for a period of 48 months, with the aim to advance research on emerging population issues in Sub-Saharan Africa (SSA). DemoStAf is built around four major population-related themes: fertility, mortalit ...
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 5

 TERMINÉ 

Data-driven models for Progression Of Neurological Disease (EuroPOND)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

EuroPOND will develop a data-driven statistical and computational modeling framework for neurological disease progression. This will enable major advances in differential and personalized diagnosis, prognosis, monitoring, and treatment and care decisions, positioning Europe as world leaders in one of the biggest societal challenges of 21st century healthcare. The inherent complexity of neurologica ...
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 9

 TERMINÉ 

Combatting Bacterial Resistance in Europe (COMBACTE-NET)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2019,

The emergence of Antibiotic-resistant bacteria (ARB) is a global problem, having recently been elevated to the top three threats identified by the World Health Organisation (WHO), and subject of numerous national and international government activities, including the Trans-Atlantic Task Force on Antimicrobial Resistance established by the US and EU presidencies. The estimated costs of ARB are aro ...
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 38

 TERMINÉ 

Novel natural products for healthy ageing from Mediterranean diet and food plants of other global sources (MediHealth)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

The main goal of the MediHealth project is to introduce a novel approach for the discovery of active agents of food plants from Mediterranean diet and other global sources to promote healthy ageing. This will be achieved through an extended and well-balanced scheme of researcher’s secondments between 5 universities and 4 enterprises from EU & Associated countries as well as 4 universities from Thi ...
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 9

 TERMINÉ 

Frontiers in Quantum Materials Control (Q-MAC)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2019,

The overarching goal of the present proposal is to exploit materials design, coherent optical methods and multiple theoretical approaches to deterministically control ordered states of strongly correlated electron materials, also referred to as “quantum” or “complex” materials. The underlying ideas can be applied to vast number of problems in materials physics, but the stated goal is that of optim ...
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 4

 TERMINÉ 

A Centre of Excellence in Computational Biomedicine (CompBioMed)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2019,

This Centre of Excellence will advance the role of computationally based modelling and simulation within biomedicine. Three related user communities lie at the heart of the CoE: academic, industrial and clinical researchers who all wish to build, develop and extend such capabilities in line with the increasing power of high performance computers. Three distinct exemplar research areas will be purs ...
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 16

 TERMINÉ 

NanoSmells: Artificial remote-controlled odorants (NanoSmell)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

"Despite years of promise, an odor-emitting component in devices such as televisions, phones, computers and more has yet to be developed. Two major obstacles in the way of such development are poor understanding of the olfactory code (the link between odorant structure, neural activity, and odor perception), and technical inability to emit odors in a reversible manner. Here we propose a novel mult ...
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 6

 TERMINÉ 

EnhANcing emergencY management and response to extreme WeatHER and climate Events (ANYWHERE)

Date du début: 1 juin 2016, Date de fin: 31 août 2019,

The ultimate purpose of ANYWHERE is to empower exposed responder institutions and citizens to enhance their anticipation and pro-active capacity of response to face extreme and high-impact weather and climate events. This will be achieved through the operational implementation of cutting-edge innovative technology as the best way to enhance citizen's protection and saving lives.ANYWHERE proposes t ...
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 32

 TERMINÉ 

SENSE - a roadmap for the ideal low light level sensor development (SENSE)

Date du début: 1 sept. 2016, Date de fin: 31 août 2019,

Over the last decade substantial improvements were made in the technologies for low light-level detection. It is expected that the coming years may bring a technology revolution in this emerging FET-relevant topic. Various European research groups have played and will play an important role in further advancing this technology since low light-level detection is very important for a lot of research ...
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 4

 TERMINÉ 

Nanomaterial FAte and Speciation in the Environment (NanoFASE)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

Concept: NanoFASE will deliver an integrated Exposure Assessment Framework, including methods, parameter values, model and guidance that will allow Industry to assess the full diversity of industrial nano-enabled products to a standard acceptable in regulatory registrations. Methods to assess how use phases, waste streams and environmental compartments (air, soil, water biota) act as “reactors” in ...
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 39

 TERMINÉ 

Gamification of participatory science for training and education purposes (GAPARS)

Date du début: 1 janv. 2017, Date de fin: 30 juin 2019,

Creating effective ways for citizen science is immensely important. Scientists in all fields increasingly rely on active public participation for experiments and analyses of complex and/or massive data, and the outreach and education possibilities of citizen science are enormous.Yet there are three key issues for any citizen science project: (i) reach out to a sufficiently large audience, (ii) low ...
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 9

 TERMINÉ 

Optical dissection of cortical motor circuits (OPTOMOT)

Date du début: 1 juin 2014, Date de fin: 31 mai 2019,

"The motor cortex plays a key role in learning and orchestrating fine voluntary movements, which dominate many aspects of our daily lives.Despite decades of research, considerable controversy remains over the functional organization of this forebrain area and its role in goal directed action. In this project we will combine cutting edge in vivo two-photon imaging, decoding methods and optogenetic ...
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 1

 TERMINÉ 

ECOPOTENTIAL: IMPROVING FUTURE ECOSYSTEM BENEFITS THROUGH EARTH OBSERVATIONS (ECOPOTENTIAL)

Date du début: 1 juin 2015, Date de fin: 31 mai 2019,

Terrestrial and marine ecosystems provide essential services to human societies. Anthropogenic pressures, however, cause serious threat to ecosystems, leading to habitat degradation, increased risk of collapse and loss of ecosystem services. Knowledge-based conservation, management and restoration policies are needed to improve ecosystem benefits in face of increasing pressures. ECOPOTENTIAL makes ...
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 47

 TERMINÉ 

Doing It Together science (DITOs) (DITOs)

Date du début: 1 juin 2016, Date de fin: 31 mai 2019,

Our project, 'Doing-It-Together Science', DITOs, represents a step change in European public engagement with science and innovation. We propose moving from a model in which scientific research, innovation, and problem-solving is mainly driven by scientific/professional institutions to one based on active public participation and capacity building with various levels and strategies of engagement in ...
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 11