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HER Imaging and Molecular Interaction Mapping in Breast Cancer (IMAGINT)
Date du début: 1 mai 2011, Date de fin: 30 avr. 2015,
The aim is to develop tools for imaging and characterising protein/protein and protein/RNA interactions in cancer using Designed Ankyrin Repeat Proteins (DARPins). DARPins are small, ultrahighly stable, antibody-like proteins that bind specific targets with high affinity in monovalent form and are readily engineered for site-specific chemical modification. The exemplar protein family will be EGFR, ...
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