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16 projets européens trouvés

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 TERMINÉ 

Astrochemistry and the Origin of Planetary Systems (CHEMPLAN)

Date du début: 1 juil. 2012, Date de fin: 30 juin 2018,

When interstellar clouds collapse to form new stars and planets, the surrounding gas and dust become part of the infalling envelopes and rotating disks, thus providing the basic material from which new solar systems are made. Instrumentation to probe the physics and chemistry in low-mass star-forming regions has so far lacked spatial resolution. I propose here an integrated observational-modeling- ...
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 1

 TERMINÉ 
I propose novel methods for understanding key aspects that are essentialto the future of Bayesian inference for high- or infinite-dimensionalmodels and data. By combining my expertise on empirical processes andlikelihood theory with my recent work on posterior contraction I shallforemost lay a mathematical foundation for the Bayesian solution touncertainty quantification in high dimensions.Decade ...
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 1

 TERMINÉ 

European Lead Factory (EUC²LID)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

The European Lead Factory concept proposed by the EUC2LID Consortium relates to the discovery of novel small molecule candidates to serve as starting points for subsequent optimization to either drug candidates or high-quality pharmacological tools for the experimental validation of targets. The concept intends to bridge academic and applied research interests. The European Lead Factory will provi ...
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 34

 TERMINÉ 
"Gas accretion and galactic winds are two of the most important and poorly understood ingredients of models for the formation and evolution of galaxies. We propose to take advantage of two unique opportunities to embark on a multi-disciplinary program to advance our understanding of the circumgalactic medium (CGM).We will use MUSE, a massive optical integral field spectrograph that we helped to de ...
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 1

 TERMINÉ 
"Sphingolipids are major components of the human cell and are involved in human pathologies ranging from lysosomal storage disorders to type 2 diabetes. Here, we propose to establish an integrated research program for the study of sphingolipid metabolism, in health and disease. We will combine state-of-the-art synthetic organic chemistry, bioorganic chemistry, analytical chemistry, molecular biolo ...
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 1

 TERMINÉ 

Analysis of the Dark Universe through Lensing Tomography (ADULT)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,

"The discoveries that the expansion of the universe is accelerating due to an unknown “dark energy”and that most of the matter is invisible, highlight our lack of understanding of the major constituentsof the universe. These surprising findings set the stage for research in cosmology at the start of the21st century. The objective of this proposal is to advance observational constraints to a level ...
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 1

 TERMINÉ 
The Decathlon project will bring together a broad range of experts and expertise to jointly work on the development of new or improved methods that are needed in the field of 1) food pathogens, 2) traceability of GMOs and 3) customs issues. The project will develop advanced methods for all three application areas with method characteristics that meet the requirements of the individual areas, as wi ...
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 18

 TERMINÉ 
The project aims to generate a fundamental understanding of electrochemical processes that will enable the conversion of excess electrical energy produced by renewable sources to chemical energy, and store it in the form of fuels or useful chemical feedstocks. This can be realized by conversions of greenhouse gas molecules within the carbon- or nitrogen-cycle. The mechanisms of the reduction of su ...
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 1

 TERMINÉ 

Science Friction (SciFri)

Date du début: 1 juil. 2011, Date de fin: 30 juin 2016,

"There is no fundamental law that dictates the necessity of losing energy in a sliding contact. In spite of its apparent simplicity, we have a relatively poor understanding of the mechanisms that determine how energy is lost when two bodies are forced to slide over one another. The SciFri project will launch a research attack on friction that will not only deepen our fundamental insight into this ...
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 2

 TERMINÉ 

Variational Approach to Random Interacting Systems (VARIS)

Date du début: 1 mai 2011, Date de fin: 30 avr. 2016,

"The goal of my mathematical research is to force a breakthrough in solving and understanding a number of long-standing open problems that are rooted in physics and chemistry. My objects of study are systems consisting of a large number of random components that interact locally but exhibit a global dependence. Typically, the components of these systems are subject to a simple microscopic dynamics ...
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 1

 TERMINÉ 
Targeted therapy remains one of the greatest challenges in modern medicine. In response, I propose synthetic, liposomal vectors capable of delivering diverse and clinically relevant therapies to targeted sites in the body, whose therapeutic action is triggered exclusively by applied light. This approach challenges traditional approaches to targeted vector-based therapies and addresses the common f ...
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 1

 TERMINÉ 
Strong emission features dominate the IR spectra of the interstellar medium of the Milky Way, galaxies in the local Universe and out to redshifts of ~3. These features are generally attributed to IR fluorescence of large Polycyclic Aromatic Hydrocarbon (PAH) molecules pumped by UV photons. These species must be abundant, ubiquitous, and an important component of the ISM. However, despite extensive ...
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 1

 TERMINÉ 

Direct Imaging of Extrasolar Planets from LBT and VLT to E-ELT (DICE)

Date du début: 1 mars 2011, Date de fin: 28 févr. 2015,

"The direct imaging of planets around other stars has begun in earnest. The main challenge in imaging these faint companions is the large contrast between star and planet. By using a combination of adaptive optics, coronagraphs, thermal wavelength imaging and point spread function modeling, current ground based telescopes can search closer to target stars for extrasolar giant planets. The applican ...
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 1

 TERMINÉ 
"Studies of high redshift galaxies require very deep Near-IR imaging. This allows the study of z=2-4 galaxies redward of the Balmer/4000 Angstrom break, and the detection of UV-bright galaxies at z>7. Two new facilities wil revolutionize these studies: the VISTA telescope built for ESO, and the Near-IR channel on WF3 for HST. They will become available at the start of the grant period. We propose ...
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 1

 TERMINÉ 
"I propose to study the charge transport properties of DNA using beyond the state-of-the-art computational tools. The charge transfer is a highly competitive phenomenon, involving multiple pathways. Such competition is at the base of the regulatory machinery of many biological processes. For the first time, the proposed software implementation will provide a systematic and analytical tool to calcu ...
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 1

 TERMINÉ 
Photosynthetic reaction centres (RCs), such as the RC from purple bacteria or photosystems I and II of plants, have their cofactors arranged in a nearly C2 symmetry. Despite this symmetrical arrangement, the electron pathway in RCs of purple bacteria and photosystem II is entirely unidirectional occurring along a single branch. In photosystem I, however, both electron transfer branches are equally ...
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 1