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The Role of Granzymes A, B and M in Sepsis (Granzymes in Sepsis)
Date du début: 15 mai 2012, Date de fin: 14 mai 2014,
Sepsis, the systemic inflammatory host response to infection, is a major health problem. Inflammation is considered the first line of defence in host-pathogen interactions. Granzymes (grzs) are a family of proteases released from secretory granules that have been suggested to have relevant effects in inflammation. Outstanding findings are the rationale to hypothesize that granzymes play an essenti ...
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