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14 projets européens trouvés

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 TERMINÉ 

DIabetes REsearCh on patient sTratification (DIRECT)

Date du début: 1 févr. 2012, Date de fin: 31 janv. 2019,

The overarching aims of the DIRECT consortium, consisting of 20 leading academic groups in diabetes and 5 EFPIA companies, are to identify biomarkers that address current bottlenecks in diabetes drug development and to develop a stratified medicines approach to treatment of type 2 diabetes with either existing or novel therapies.There is heterogeneity in who develops diabetes, the rate at which th ...
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 27

 TERMINÉ 

Targets and biomarkers for antiepileptogenesis (EPITARGET)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,

Epilepsy is a devastating condition affecting over 50 million people worldwide. This multidisciplinary project is focused on the process leading to epilepsy, epileptogenesis, in adults. Our main hypothesis is that there are combinations of various causes, acting in parallel and/or in succession, that lead to epileptogenesis and development of seizures. Our central premise and vision is that a comb ...
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 20

 TERMINÉ 

European Medical Information Framework (EMIF)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

In response to the need to tackle increasingly complex medical research questions, a growing amount of human health data is being collected, either in routine Electronic Healthcare Record (EHR) databases, through research-driven cohort studies, in biobanks or related efforts. However, data sources are typically fragmented and contain information gaps which prevent their full exploitation. EMIF aim ...
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 64

 TERMINÉ 

The effect of intracoronary reinfusion of bone marrow-derived mononuclear cells (BM-MNC) on all-cause mortality in acute myocardial infarction (BAMI)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2017,

Although the long term prognosis of patients suffering acute myocardial infarction (AMI) has improved since the introduction of reperfusion therapies and primary angioplasty, the 1 year mortality of patients with AMI and resultant left ventricular systolic dysfunction (LVSD) is still as high as 13%. A major reason for the high morbidity and mortality is that the heart has an inadequate regenerativ ...
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 23

 TERMINÉ 

Biodegradable Magnetic Stent for Coronary Artery Luminal Regeneration (BIOMAGSCAR)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,

By 2010 1.5 million stents per year will be deployed in Europe. Although outcome for patients has improved, stents still fail because of the occurrence of restenosis and thrombosis at the site of implantation. While drug eluting stents have helped to reduce the problem of restenosis, neointimal proliferation causing restenosis can still occur. Additional concerns exist regarding drug eluting stent ...
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 8

 TERMINÉ 

Mechanisms of post-mating sexual selection in a marine invertebrate (POMASE)

Date du début: 1 sept. 2014, Date de fin: 31 août 2016,

"Sexual selection continues after mating up to the point of fertilization (post-mating sexual selection, PMSS) through intersexual selection (cryptic female choice, CFC) and intrasexual selection between ejaculates (sperm competition, SC). Although PMSS is ubiquitous in nature, the mechanisms and selective processes underlying both CFC and SC have remained largely enigmatic. CFC is often thought t ...
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 1

 TERMINÉ 

ADenoViruses as novel clinical treatments (ADVANCE)

Date du début: 1 avr. 2012, Date de fin: 31 mars 2016,

ADVance is designed to integrate 8 leading academic centres and 4 private companies under a single umbrella to create an opportunity to train young scientists in adenovirus (AdV) research. Our full partners and industrial partners represent internationally leading academic centres of excellence in key facets of research into the basic biology of AdV and their application as vectors for clinical p ...
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 13

 TERMINÉ 

Mechanisms of prevention of type 2 diabetes by lifestyle intervention in subjects with pre-diabetes or at high-risk for progression (DEXLIFE)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

"Type 2 diabetes (T2DM) is preventable by sustained changes in diet and physical exercise. Despite this, modern societies are already approaching 10% population prevalence of diabetes, and another 15% with pre-diabetes. The costs of T2DM are huge, approaching 10% of all health costs. Prevention of diabetes is a priority for national healthcare agencies and for the health insurance industry. Inve ...
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 12

 TERMINÉ 

BESAFE Biodiversity and Ecosystem Services: Arguments for our future Environment (BESAFE)

Date du début: 1 sept. 2011, Date de fin: 31 août 2015,

In order to protect biodiversity, policy makers increasingly require demonstration of its value. BESAFE will usecase studies to investigate how much importance people attribute to alternative arguments for the protectionof biodiversity and in particular how this relates to ecosystem services. It will focus on the arguments used at different governance levels and in different ecological, socio-econ ...
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 16

 TERMINÉ 

Nanostructured composite materials (NANOCOM)

Date du début: 1 avr. 2011, Date de fin: 31 mars 2015,

In the search for new materials with enhanced functionality, glassy nanocomposites comprising of nanoparticles of different nature in glassy matrix are of special interest. In the case of metal nanoparticles this is because the pronounced surface plasmon resonance, which dominates the optical properties of glass-metal nanocomposites (GMN) and provides high optical nonlinearity of GMN due to additi ...
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 3

 TERMINÉ 

European Training Network on Cancer-Induced Bone Diseases (BONE-NET)

Date du début: 1 févr. 2011, Date de fin: 31 janv. 2015,

Several cancers are prone to metastasize to bone. Combating bone metastasis, especially the early dissemination of cancer cells in bone, requires basic research knowledge, skills in different technologies and longstanding clinical experience in order to make clinically significant progress. BONE-NET is a european consortium with complementary expertises in the fields of cancer and bone. It brings ...
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 11

 TERMINÉ 

Molecular modelling of the cannabinoid CB1 receptor homodimer and its interaction with ligands: the role of membrane cholesterol and the CRIP1a protein (CannabiDim)

Date du début: 1 août 2012, Date de fin: 31 juil. 2014,

The cannabinoid CB1 receptor (CB1R) is an attractive molecular target for the treatment of substance abuse, drug addiction, schizophrenia, bipolar disorder, motor dysfunction including Huntington’s disease, as well as cardiometabolic disease and metabolic syndrome.The general aim of the project is to investigate in silico the phenomenon of the homodimerization of the CB1R, the interaction of the C ...
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 1

 TERMINÉ 

High-throughput Production of FunctIonal 3D images of the brain (HIGH PROFILE)

Date du début: 1 avr. 2011, Date de fin: 30 juin 2014,

"HIGH PROFILE combines industrial and clinical driven R&D activities dealing with image diagnostic platforms for the central nervous system. The project’s approach is to progress state-of-the-art by integrating imaging equipment for diagnostics –including algorithms, equipment and infrastructure for massive image processing and simulation– to support combinations of images from different medical e ...
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 20

 TERMINÉ 

BIOcontamination Specific Modeling in HAbitats Related to Space (BIOSMHARS)

Date du début: 1 juin 2011, Date de fin: 31 mai 2013,

"BIOSMHARS is the first phase of a Europe - Russia research effort aiming to develop the scientific and technical tools enabling to have a comprehensive approach of biocontamination inside manned spacecrafts, and to develop appropriate countermeasures. BIOSMHARS will develop and calibrate a mathematical model predicting the transportation of bioaerosols in a closed environment and the induced bioc ...
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 6