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"COPD is the only chronic disease with an increasing mortality and it will constitute the 4th leading cause of death by 2035 world wide. To alleviate the burden of COPD an accurate and easy diagnosis in the early stages of COPD needs to be developed. Many studies strongly suggest that there is an individual genetic susceptibility to COPD: only 10-15% of all smokers develop COPD. In another study, ...