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"Glioblastoma (GBM) is a rare (2-3 incidences in 100,000) and fatal disease. Each year, approximately 13,000 new cases of GBM are diagnosed in Europe. The 5-year survival rate of this highly aggressive tumor entity under conventional therapy is less than 6%. Currently available therapeutic options neglect the individuality of each patients’ disease and only temporarily influence tumor progression ...

Today's major challenges for manufacturing companies, operating under productivity pressures, greater product variability and environmental constraints, are clearly identified as global cooperation with multiple supply chain partners, production optimization, and tracking and management of information to meet new requirements like traceability, security, sustainability. These requirements lead to ...