7 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
European Training in Neural Regulation of Intestinal Function (NeuroGut)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,
"Neurogastroenterology is a new and emerging medical/scientific subspecialty that currently has no formal training opportunities in medicine and related disciplines. It includes basic science aspects (neurophysiology, neurobiology, neuropsychology, psychophysiology) and clinical aspects (gastroenterology, neurology, internal medicine, surgery, psychology, psychosomatic medicine) of the neural cont ...
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12
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TERMINÉ
Preclinical development of drugs and drug delivery technology for the treatment of inherited photoreceptor degeneration (DRUGSFORD)
Date du début: 1 sept. 2012, Date de fin: 31 août 2016,
Dysregulation of cGMP is a pathological hallmark of inherited retinal degenerations (RD) affecting photoreceptors, the sensory cells of the retina. These RDs, including Retinitis Pigmentosa, Lebers Congenital Amaurosis, and Achromatopsia, are major causes of blindness, affecting approximately one in every 2000 individuals worldwide, and remain without effective treatment. In photoreceptors, cGMP i ...
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6
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TERMINÉ
A systems biology approach to dissect cilia function and its disruption in human genetic disease (SYSCILIA)
Date du début: 1 juin 2010, Date de fin: 31 mai 2015,
AIM: To identify the molecular mechanisms characterizing cilium function, and the discrete perturbations associated with dysfunction caused by mutations in inherited ciliopathies, applying a systems biology approach. BACKGROUND: Cilia are microtubule-based, centriole-derived projections from the cell surface. They transduce extracellular signals and regulate key processes in which signals of the e ...
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17
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TERMINÉ
Optical and adaptational limits of vision (OPAL)
Date du début: 1 avr. 2011, Date de fin: 31 mars 2015,
"Despite extensive research on the optics of the eye and the neuronal processing of the optical image that is projected on the retina, a number of basic questions are surprisingly unclear. Combining the expertise of 5 University-based European laboratories with a long history of scientific accomplishments, a well established industrial partner, and a high-ranking international advisory board, this ...
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6
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TERMINÉ
Innovative Techniques and Models to Study Glia-Neuron Interactions (EdU-GLIA)
Date du début: 15 sept. 2009, Date de fin: 14 sept. 2013,
It became evident over the last 20 years that glial cells are involved in virtually every aspect of nervous system function. Neurons and glia exchange chemical signals that are essential for the normal function of the nervous system, and are crucial in disease. Recently it was discovered that glial cells also act as neural stem cells both in early development and adulthood, and in synapse formatio ...
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14
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TERMINÉ
Restoring Mueller glia cell – photoreceptor interactions with Crumbs (CRUMBS IN SIGHT)
Date du début: 1 avr. 2008, Date de fin: 31 mai 2012,
"Mutations in the Crumbs homologue 1 (CRB1) gene cause photoreceptor degeneration resulting in progressive retinitis pigmentosa (RP) or Leber congenital amaurosis (LCA), which both currently are untreatable blinding diseases. CRB1 is localized in Mueller glia cells at a subapical region (SAR) adjacent to adherens junctions between Mueller glia cells and photoreceptors. Loss of CRB1 function result ...
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8
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TERMINÉ
Visual Impairment and Degeneration: A Road-map for Vision Research within Europe (EuroVisionNet)
Date du début: 1 mars 2008, Date de fin: 29 févr. 2012,
The coordination project EuroVisionNet aims to link the research activities and policies of the European vision research community and to overcome the national fragmentation, therewith intends to become an essential “instrument” for vision research in the 21st century. To reach this goal the following 4 objectives will be addressed: (1) scientific integration of European vision research; (2) colla ...
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