Plus de 40 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Clinical proof of concept through a randomised phase II study: a combination of immunotherapy and stereotactic ablative radiotherapy as a curative treatment for limited metastatic lung cancer (IMMUNOSABR)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2022,
IMMUNOSABR is geared towards opening up a new paradigm in treating metastatic cancer by obtaining clinical proof of concept for a novel bi-modal curative treatment strategy. High precision stereotactic ablative radiotherapy (SABR) is combined with immunotherapy to form a powerful synergistic anti-tumour strategy. The approach relies on the direct cytotoxic effect of SABR, the abscopal effect of ra ...
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17
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TERMINÉ
Parallel network-based biocomputation: technological baseline, scale-up and innovation ecosystem (Bio4Comp)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,
Many technologically and societally important mathematical problems are intractable for conventional, serial computers. Therefore, a significant need exists for parallel-computing approaches that are capable to solve such problems within reasonable time frames. Recently, part of our consortium demonstrated proof-of-principle of a parallel-computation system in which a given combinatorial problem i ...
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6
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TERMINÉ
Decisions in metabolic inflammation of the liver: Adhesive interactions involved in leukocyte retention and resolution of inflammation in metabolic-inflammatory liver disease (DEMETINL)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,
Resolution of acute inflammation, involving limiting further leukocyte recruitment, apoptosis and clearance of inflammatory cells via macrophages as well as egress of the inflammatory cells, is operative in acute inflammation but dysfunctional in chronic inflammatory disease. In the latter scenario, the retention and activation of leukocytes in the inflamed tissue linked with failure to resolve in ...
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1
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TERMINÉ
Groups, Dynamics, and Approximation (GrDyAp)
Date du début: 1 oct. 2016, Date de fin: 30 sept. 2021,
Eversince, the study of symmetry in mathematics and mathematical physics has been fundamental to a thourough understanding of most of the fundamental notions. Group theory in all its forms is the theory of symmetry and thus an indispensible tool in many of the basic theoretical sciences.The study of infinite symmetry groups is especially challenging, since most of the tools from the sophisticated ...
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1
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TERMINÉ
Homogeneous Structures, Constraint Satisfaction Problems, and Topological Clones (CSP-Infinity)
Date du début: 1 oct. 2016, Date de fin: 30 sept. 2021,
The complexity of constraint satisfaction problems (CSPs) is a field in rapid development, and involves central questions in graph homomorphisms, finite model theory, reasoning in artificial intelligence, and, last but not least, universal algebra. In previous work, it was shown that a substantial part of the results and tools for the study of the computational complexity of CSPs can be generalise ...
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1
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TERMINÉ
Integration of climate change adaptation into the work of local authorities (LIFE LOCAL ADAPT)
Date du début: 1 juil. 2016, Date de fin: 30 juin 2021,
Background
Responsibility for infrastructure is devolved to the regional or local level in many parts of the EU. However, many small and medium-sized authorities lack the knowledge and capacity to address the challenges posed by the need for climate change adaptation (CCA). LIFE LOCAL ADAPT has been designed to identify specific threats at local level and ...
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7
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TERMINÉ
The molecular interface between cell cycle and redox regulation (REDOXCYCLE)
Date du début: 1 juil. 2016, Date de fin: 30 juin 2021,
Aberrant cell cycle and redox regulation are hallmarks of cancer. While cell cycle and redox signaling are extensively studied, it remains poorly understood how both communicate in physiological conditions. One reason is the emphasis on oxidative stress as a signature of cancer cells. Only recently, emerging evidence indicates that reactive oxygen species (ROS) also function as signaling molecules ...
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1
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TERMINÉ
Novel applications based on organic biluminescence (BILUM)
Date du début: 1 avr. 2016, Date de fin: 31 mars 2021,
Organic semiconducting molecules often make for very good luminescent materials. Fundamental excitations are localized on single molecules, which is in stark contrast to inorganic semiconductors, such that exchange interactions lead to energetically distinct singlet and triplet states. The singlet-excited state is the origin of conventional fluorescence. However, once an excitation is in the molec ...
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1
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TERMINÉ
Transcription Factor-mediated Neuronal Cell Fate Programming in Human Stem Cells (ProNeurons)
Date du début: 1 mars 2016, Date de fin: 28 févr. 2021,
The discovery of pluripotent stem cells has expanded the working modes in biology towards the reverse engineering of specific cell types. Unlike studying developmental phenomena in vivo, we are now theoretically able to mimic some of these processes in a dish. The use of human induced pluripotent stem (iPS) cells facilitates studying the genesis of human cell types in an ethically approved setting ...
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1
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TERMINÉ
A multicenter phase IIb study using HLA-unmatched allogeneic placenta-derived stromal cells (PLX-PAD) for the treatment of severe critical limb ischemia accompanied by mechanistic studies (PACE)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
PACE aims to transform the treatment of patients suffering from critical limb ischemia (CLI), a disease with high medical need, because of limited treatment options and poor outcome by applying a novel, off-the-shelf allogeneic placenta-derived stromal cell product (PLX-PAD). Despite improvements in medical care and revascularization, patients with CLI continue to have a high risk of major amputat ...
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9
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TERMINÉ
Regeneration of the adult zebrafish brain (ZF-BrainReg)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,
The goal of this research proposal is to unravel the cellular and molecular mechanisms for the ability of the adult zebrafish brain to regenerate itself after a lesion, and to compare these mechanisms in the non-regenerating mammalian brain. The corresponding mechanisms, if reactivated, may rekindle regeneration also in mammalian brains. Specifically, we focus on identifying the endogeneous stem a ...
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1
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TERMINÉ
Effect of ALlopurinol in addition to hypothermia for hypoxic-ischemic Brain Injury on Neurocognitive Outcome (ALBINO)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,
Neonatal hypoxic-ischemic encephalopathy (HIE) is a major cause of death or long-term disability in infants born at term in the western world, affecting about 1-4 per 1.000 life births and consequently about 5-20.000 infants per year in Europe.Hypothermic treatment became the only established therapy to improve outcome after perinatal hypoxic-ischemic insults. Despite hypothermia and neonatal inte ...
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18
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TERMINÉ
SEcure Network Coding for Reduced Energy nexT generation Mobile Small cells (SECRET)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
SECRET is a collaborative European Training Network (ETN) committed to create an “excellent” educational training platform; that is multi-disciplinary and intersectoral in nature, for Early Stage Researchers (ESRs) in the field of wireless communications and networking. In this dynamic field, the challenges are always evolving and more stringent in line with market expectation, and socio-economica ...
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8
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TERMINÉ
The nanoparticle-scope : a new integrated instrument for accurate and reproducible physico-chemical characterisation of nanoparticles (npSCOPE) (npSCOPE)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
The npSCOPE project aims at developing a new integrated instrument (the nanoparticle-scope) optimised for providing a complete physico-chemical characterisation of nanoparticles both in their pristine form or embedded in complex matrices such as biological tissues. Using sophisticated correlative data processing methodologies and algorithms based on statistical methods in conjunction with appropri ...
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9
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TERMINÉ
Spins for Efficient Photovoltaic Devices based on Organic Molecules (SEPOMO)
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,
Organic solar cells (OSCs) have the potential to become an environmental friendly, inexpensive, large area and flexible photovoltaics technology. Their main advantages are low process temperatures, the potential for very low cost due to abundant materials and scalable processing, and the possibility of producing flexible devices on plastic substrates. To improve their commercialization capacity, t ...
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11
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TERMINÉ
Rich, Structured Models for Scene Recovery, Understanding and Interaction (RSM)
Date du début: 1 oct. 2015, Date de fin: 30 sept. 2020,
Computer vision has gained considerable momentum in recent years – both in industry and academia. There seems to be a spirit that the time is ripe to realize grand goals and to bring computer vision from the lab into real life. But is a vision system already as good as a human is? The answer is: “Unfortunately, not yet.” Given a single image, a child can describe the objects and their relationship ...
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1
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TERMINÉ
Environmental modulators of the immune cell balance in health and disease (ENVIROIMMUNE)
Date du début: 1 août 2015, Date de fin: 31 juil. 2020,
The incidence of autoimmune diseases in developed societies is increasing at high rates, but the underlying cause for this phenomenon has not been elucidated yet. Since the genetic architect remains considerably stable, this increase is likely associated with changes in the environment. Autoimmunity is linked to an imbalance of pro-inflammatory Th17 cells and anti-inflammatory Foxp3+ regulatory T ...
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2
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TERMINÉ
Troy+ stomach stem cells in homeostasis, repair and pathogenesis (Troy Stem Cells)
Date du début: 1 août 2015, Date de fin: 31 juil. 2020,
The adult mammalian stomach can be divided into three distinct parts: From the proximal fore-stomach over the corpus to the distal pylorus. Due to constant exposure to mechanical stress and to hostile contents of the lumen, highly specialized cell types have to be constantly reproduced in order to maintain the function of the gastrointestinal tract. Recently, the applicant identified Troy+ chief c ...
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2
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TERMINÉ
Application of omics-based strategies for improved diagnosis and treatment of endocrine hypertension (ENSAT-HT)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,
Arterial hypertension affects up to 45% of the general population and is responsible for 7.1 million deaths per year worldwide. Although a large therapeutic arsenal exists, blood pressure control is sub-optimal in up to two thirds of patients. Yet, even small increments in blood pressure are associated with increased cardiovascular risk, with 62% of cerebrovascular disease and 49% of ischemic hear ...
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13
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TERMINÉ
A multidisciplinary approach to cell division: From human oocyte to synthetic biology (DivIDe)
Date du début: 1 avr. 2016, Date de fin: 31 mars 2020,
The cell is the universal unit of living matter, and there cannot be propagation of life without cell division. DivIDe aims to investigate the mechanisms and principles of cell division and to reproduce them in vitro with synthetic approaches. Crucial to cell division is the mitotic spindle, a structure whose main duty is the separation of chromosomes. The spindle is made of microtubules (MT), mol ...
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9
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TERMINÉ
Clinical development of a dendritic-cell vaccine therapy for acute myeloid leukaemia (AML-VACCiN)
Date du début: 1 janv. 2016, Date de fin: 31 mars 2020,
Eradicating minimal residual disease (MRD) in patients with acute myeloid leukaemia (AML) is an area of high unmet medical need. AML is a deadly rare disease that affects both children and adults. Approximately 45% of younger AML patients who are treated will be cured, and in older patients (>60 years of age), 85% will relapse and die within 2 years.Immunotherapy has great potential for treating M ...
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12
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TERMINÉ
Designing for People with Dementia: designing for mindful self-empowerment and social engagement (MinD)
Date du début: 1 mars 2016, Date de fin: 29 févr. 2020,
This project aims to help people with dementia engage in social contexts to improve psychosocial wellbeing. People who are affected by Alzheimer’s disease or other dementias often face cognitive, behavioural and psychosocial difficulties, including impairment and degeneration of memory and of perceptions of identity. In a social context, this can cause difficulties of recognizing, relating to and ...
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12
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TERMINÉ
Directly Modulated Lasers on Silicon (DIMENSION)
Date du début: 1 févr. 2016, Date de fin: 31 janv. 2020,
DIMENSION establishes a truly integrated electro-optical platform, extending the silicon (Bi)CMOS and silicon photonics platform with III-V photonic functionality. The III-V integration concept is fully CMOS compatible and offers fundamental advantages compared to state-of-the art integration approaches. After bonding and growing ultra-thin III-V structures onto the silicon front-end-of-line, the ...
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6
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TERMINÉ
Intelligent Parkinson eaRly detectiOn Guiding NOvel Supportive InterventionS (i-PROGNOSIS)
Date du début: 1 févr. 2016, Date de fin: 31 janv. 2020,
Transition from healthy status to Parkinson’s Disease (PD) is vaguely tractable, since symptoms can be so subtle in the early stages that they go unnoticed. Lack of biomarkers and/or findings on routine MRI and CT scans, PD is left undiagnosed for years, gradually affecting the life of over 6.5 million of older adults (>55-60 yrs) worldwide, increasing the risk of their health deterioration. Epide ...
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11
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TERMINÉ
Robust Internal Thermal Insulation of Historic Buildings (RIBuild)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,
RIBuild will strengthen the knowledge on how and under what conditions internal thermal insulation is to be implemented in historic buildings, without compromising their architectural and cultural values, with an acceptable safety level against deterioration and collapse of heavy external wall structures. The general objective of RIBuild is to develop effective, comprehensive decision guidelines t ...
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10
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TERMINÉ
Wireless In-Body Environment (WiBEC)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
WiBEC (Wireless In-Body Environment Communications) is an Innovative Training Network for 16 young researchers, who will be recruited and trained in coordinated manner by Academia, Industry, and Medical Centres. This training will address the Social, Health, and Technology challenges of the H2020:Wireless In-Body Devices. WiBEC’s main objective is to provide high quality and innovative doctoral tr ...
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9
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TERMINÉ
Orchestration and Reconfguration Control Architecture (ORCA)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,
ORCA offers experimentation facilities to promote wireless innovation in several market segments, including manufacturing, automotive industry, healthcare, ambient assistant living, public events, home automation, and utilities. Within the manufacturing market, for instance, application requirements vary from very low latency, up to real-time 3D video-driven interaction between collaborative robot ...
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8
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TERMINÉ
Generalized Operational FLEXibility for Integrating Renewables in the Distribution Grid (GOFLEX)
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2019,
The GOFLEX project will innovate, integrate, further develop and demonstrate a group of electricity smart-grid technologies, enabling the cost-effective use of demand response in distribution grids, increasing the grids’ available adaptation capacity and safely supporting an increasing share of renewable electricity generation. The GOFLEX smart grid solution will deliver flexibility that is both g ...
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12
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TERMINÉ
RANGER: RAdars for loNG distance maritime surveillancE and SaR opeRations (RANGER)
Date du début: 1 mai 2016, Date de fin: 31 oct. 2019,
EU trade, transport, tourism and economic development are directly dependent on open and safe seas and oceans. EU's maritime borders are widely spread including various topologies from open sea to semi-enclosed cabins with islands and islets. This poses great challenges that affect securing maritime border areas. Failing to protect against a wide array of maritime threats and risks may result in t ...
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10
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TERMINÉ
New enzymatic oxidation/oxyfunctionalization technologies for added value bio-based products (EnzOx2)
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2019,
Sustainable production of chemical building blocks and other added value products from plant biomass is required for a bio-based economy. However, the biomass biorefineries should benefit not only from the use of renewable feedstocks but also from greener and more efficient bio-chemical technologies. Previous projects have shown the potential of oxidative enzymes in the production of some added va ...
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11
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TERMINÉ
E+ JMD CARTOGRAPHY
Date du début: 15 oct. 2014, Date de fin: 14 oct. 2019,
REFERENCE: 553659-EPP-1-2014-1-DE-EPPKA1-JMD-MOB_CARTOTITLE: Cartography Master of Science, CARTOObjectiveThe Cartography Master of Science (CARTO) aims to provide qualifications to give students access to professions in the area of cartography research, map publishing, Internet mapping and geographic information systems (GIS).Course durationTwo years (120 ECTS credits).Brief descriptionOver four ...
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4
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TERMINÉ
Groundwater and Global Change - Impacts and Adaptation
Date du début: 15 oct. 2014, Date de fin: 14 oct. 2019,
REFERENCE: 553633-EPP-1-2014-1-NL-EPPKA1-JMD-MOB_G-watCHTITLE: Erasmus Mundus Joint Master Programme in Groundwater and Global Change – Impacts and Adaptation, GROUNDWATCHObjectiveThe Erasmus Mundus Joint Master Programme in Groundwater and Global Change – Impacts and Adaptation (GROUNDWATCH) aims to address the current gaps in higher education with regard to the understanding of the interactions ...
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3
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TERMINÉ
Vietnamese-European Knowledge and Technology Transfer Education Consortium
Date du début: 15 oct. 2016, Date de fin: 14 oct. 2019,
Vietnam enjoyed 20 years of economic growth following the adoption of Doi Moi or “economic renovation” (°1986). It marked a policy shift from central planning toward a mixed economy, termed as “socialist market economy”. At the same time, the role of universities all over the world changed from producing knowledge for knowledge’s sake to being a source of innovation and a motor of entrepreneurial ...
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6
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TERMINÉ
Principles of Polarity – Integrating genetic, biophysical and computational approaches to understand cell and tissue polarity (PolarNet)
Date du début: 1 oct. 2015, Date de fin: 30 sept. 2019,
The ability of cells to polarize underlies the most basic biological functions such as motility and response to external challenges, but also the formation and maintenance of tissues in a multicellular organism. The importance of cell polarity is underscored by the fact that cell polarity is essential for animal development and is perturbed in disease states such as cancer. Understanding cell pola ...
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9
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TERMINÉ
ANtibioticS and mobile resistance elements in WastEwater Reuse applications: risks and innovative solutions (ANSWER)
Date du début: 1 oct. 2015, Date de fin: 30 sept. 2019,
In response to the increasing problem of water shortage, the reuse of treated urban wastewater is considered the most suitable and reliable alternative for sustainable water management and agricultural development. In spite of the benefits associated with this practice, major concerns currently exist, related to the adverse effects regarding chemical and biological contaminants of emerging concern ...
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10
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TERMINÉ
Erasmus Mundus Master in Nanoscience and Nanotechnology
Date du début: 20 sept. 2015, Date de fin: 19 sept. 2019,
Objective The objective of the Erasmus Mundus Master in Nanoscience and Nanotechnology is to provide a top quality and broad multidisciplinary education in the emerging field of nanoscience and nanotechnology, coupled with an individual top-level specialization in one of five defined areas of nanoscience and nanotechnology: nanophysics, nanochemistry, nanoelectronics, biophysics or nanobiotechnolo ...
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4
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TERMINÉ
Refugees
Date du début: 1 sept. 2016, Date de fin: 31 août 2019,
We have decided to implement this project, because we see the need to familiarize the migrants with our European nations and vice versa. European states have decided to take in a large number of migrants in their lives. The goal is to gradually integrate them into our community. We will analyze problems associated with their integration into the European community and we will propose a partial so ...
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7
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TERMINÉ
Towards a Shared European Logistics Intelligent Information Space (SELIS)
Date du début: 1 sept. 2016, Date de fin: 31 août 2019,
SELIS is aimed at delivering a ‘platform for pan-European logistics applications’ by:- Embracing a wide spectrum of logistics perspectives and creating a unifying operational and strategic business innovation agenda for pan European Green Logistics.- Establishing an exceptionally strong consortium of logistics stakeholders and ICT providers, that can leverage EU IP from over 40 projects so as to c ...
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38
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TERMINÉ
Integrating Technology into Mental Health Care Delivery in Europe (ICare)
Date du début: 1 sept. 2015, Date de fin: 31 août 2019,
The evidence base of Internet-based interventions in the prevention and treatment of mental health conditions has rapidly grown in the past decade. Yet many European countries (e.g., Germany, Austria, Switzerland, Great Britain, The Netherlands, Spain) have not implemented these promising approaches into health systems. Individuals with risk conditions or distinct mental health problems interested ...
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13
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TERMINÉ
EXTREME Dynamic Loading - Pushing the Boundaries of Aerospace Composite Material Structures (EXTREME)
Date du début: 1 sept. 2015, Date de fin: 31 août 2019,
The European industry is currently a world leader in aviation and to maintain its leading position and competitiveness in the dynamic global market, Europe’s industry must develop quickly and efficiently high quality products by meeting time-critical market demands and customers’ needs. Industrial competition is becoming fiercer not only from established regions, such as the USA, but from new eme ...
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