2 projets européens trouvés
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TERMINÉ
Scaling-up biodegradable nanomedicines for multimodal for multimodal precision cancer immunotherapy (PRECIOUS)
Date du début: 1 mai 2016, Date de fin: 30 avr. 2021,
PRECIOUS aims at scaling-up biodegradable nanomedicines for multimodal precision cancer immunotherapy.With 3.5 million cancer patients in Europe every year, new cancer medicines are eagerly awaited, notably for prostate and ovarian cancer.Systemically applied new immunotherapies are promising, but their toxicity is a hurdle. Vaccination against cancer is safe but rather disappointing: the microenv ...
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TERMINÉ
REgeneration of inner ear hair cells with GAmma-secretase INhibitors to regain hearing in patients with sensorineural hearing loss (REGAIN)
Date du début: 1 mai 2015, Date de fin: 31 oct. 2018,
Hearing loss is a chronic non-communicable disease disabling over 328 million adults, and 32 million children worldwide. Sensorineural hearing loss due to loss of auditory hair cells was long thought to be irreversible. However, recent animal studies have demonstrated that pharmacological inhibition of cell signalling via Notch receptors using gamma-secretase inhibitors (GSIs) can regenerate hair ...
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