5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Long-term effects of early nutrition on later health (EARLYNUTRITION)
Date du début: 1 févr. 2012, Date de fin: 31 oct. 2017,
Nutrition during early development has an important impact on later health, particularly through greater obesity risk, as demonstrated by FP6 EARNEST. EarlyNutrition explores the current key hypotheses on likely causes and pathways to prevention of early life origins of obesity (specifically adiposity) and associated disorders. We bring extraordinary expertise and study populations of 470,000 indi ...
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40
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TERMINÉ
Development of very promising humanized therapeutic mAbs efficiently neutralizing a novel immunosuppressive pathway involved in a wide range of cancers (TumAdoR)
Date du début: 1 sept. 2013, Date de fin: 31 août 2017,
Studies have demonstrated the importance of CD73 in the spread of cancer. Overexpressed in numerous cancer types, this enzyme leads to the production of high amounts of extracellular Adenosine, creating an immunosuppressive microenvironment, and contributing to tumor proliferation and dissemination. Neutralizing its activity represents a highly potent and innovative therapy.Following on the recent ...
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8
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TERMINÉ
Impact of Prenatal Stress on BRAIN AGEing (BRAINAGE)
Date du début: 1 mars 2012, Date de fin: 28 févr. 2017,
Healthy brain ageing is a major determinant of quality life-long health, allowing integration into society at all ages. Human epidemiological and animal studies indicate that in addition to life style and genetic factors, environmental influences in prenatal life have a major impact on brain ageing and age-associated brain disorders. We hypothesize that: (1) prenatal stress programs early brain ag ...
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10
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TERMINÉ
WINTHERapeutics: development of a systems biology method to predict efficacy of cancer drugs to optimize individualized therapeutic decision and improve clinical outcome for cancer patients (WINTHER)
Date du début: 1 mars 2013, Date de fin: 28 févr. 2015,
Relevance: WINTHER project focuses on the development and validation, in 24 months, of industry supported new tools and computational methods, to predict efficacy of drugs in cancer patientsCurrent medical needs: Selection of cancer targeted therapies based on molecular abnormalities (mutations /amplifications/ translocations) benefit today only to 10-40% of patients. For the remaining majority, ...
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12
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TERMINÉ
CO2 Site Closure Assessment Research (CO2CARE)
Date du début: 1 janv. 2011, Date de fin: 31 déc. 2013,
CO2CARE aims to support the large scale demonstration of CCS technology by addressing the research requirements of CO2 storage site abandonment. It will deliver technologies and procedures for abandonment and post-closure safety, satisfying the regulatory requirements for transfer of responsibility. The project will focus on three key areas: well abandonment and long-term integrity; reservoir mana ...
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