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Plus de 40 projets européens trouvés

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 TERMINÉ 

Multiple manifestations of genetic and non-genetic factors in Multiple Sclerosis disentangled with a multi-omics approach to accelerate personalised medicine (MultipleMS)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

The complex interactions between genetic and non-genetic factors produce heterogeneities in patients as reflected in the diversity of pathophysiology, clinical manifestations, response to therapies, disease development and progression. Yet, the full potential of personalized medicine entails biomarker-guided delivery of efficient therapies in stratified patient populations.MultipleMS will therefor ...
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 25

 TERMINÉ 

Precision measurements to discover new scalar and vector particles (PRECISION)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2021,

The Standard Model of particle physics successfully describes all known particles and their interactions. However, questions like the nature of dark matter or the hierarchy of masses and couplings of quarks and leptons remain to be understood. Hence, one searches for new phenomena that will lead to a superior theory that can explain these questions. All such theories introduce additional quantum c ...
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 1

 TERMINÉ 

Reactivity and Assembly of Multifunctional, Stimuli-responsive Encapsulation Structures (RAMSES)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2021,

In biochemical systems, combinations of specialized molecular entities are precisely arranged to give highly complex architectures. Sophisticated functionality, such as the selective chemical transformation of substrates in enzymes, emerges from the interplay of the individual components that are often grouped around a nanoscopic cavity. Control mechanisms based on the cooperative binding of signa ...
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 1

 TERMINÉ 

Big Data Management and Analytics

Date du début: 1 sept. 2016, Date de fin: 31 oct. 2021,

...e amounts of heterogeneous data for decision-making purposes. The curriculum is jointly delivered by Université libre de Bruxelles (ULB), Belgium, Universitat Politècnica de Catalunya (UPC), Spain, Technische Universität Berlin (TUB), Germany, Technische Universiteit Eindhoven (TU/e), the Netherlands, and Université François Rabelais Tours (UFRT), France. Academic partners around the world and par ...
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 5

 TERMINÉ 

Dissecting the role of the ubiquitin proteasome system in the pathogenesis and therapy of B-cell malignancies (BCM-UPS)

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

B-cell malignancies are characterized by high levels of genomic instability, which critically contribute to their pathogenesis and evolution. Recently, the fundamental role of the ubiquitin proteasome system (UPS) in maintaining genome integrity has been appreciated. Two major new therapeutic modalities in B-cell malignancies, proteasome inhibitors and imunomodulatory drugs (IMiDs), target the UPS ...
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 2

 TERMINÉ 

Post-transcriptional Regulation of Germinal Center B Cell Responses in Immunity and Disease (GCB-PRID)

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

Antibodies secreted by B cells of the adaptive immune system establish an essential barrier against bacteria and viruses and their presence is the hallmark of protective vaccinations. B cells are licensed for their tasks during germinal center (GC) reactions and differentiation into antibody-secreting plasma cells. Unfortunately, B cell-derived autoantibodies and proinflammatory cytokines can caus ...
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 2

 TERMINÉ 

Individualised medicine in chronic inflammatory skin diseases (IMCIS)

Date du début: 1 juil. 2016, Date de fin: 30 juin 2021,

More than 100 million EU citizens suffer from chronic inflammatory skin diseases such as psoriasis and atopic eczema (AE). The diseases imply a devastating life quality similar to that of cancer, and cause direct socio-economic costs in the magnitude of 100 billion Euro each year in the EU. Despite all efforts, psoriasis and AE remain undertreated and the concept of individualised (also called pre ...
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 2

 TERMINÉ 

The origin of heavy elements: a nuclear physics and astrophysics challenge (EUROPIUM)

Date du début: 1 mai 2016, Date de fin: 30 avr. 2021,

Where in the universe are heavy elements synthesized? How are these elements produced? These are two exciting and interdisciplinary questions in nuclear astrophysics today and will be investigated in my ERC project EUROPIUM. The favored astrophysical sites are neutrino-driven winds following core-collapse supernovae and neutron star mergers, where extreme conditions enable the rapid neutron captur ...
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 2

 TERMINÉ 

Enhancing electrocatalysis in low temperature fuel cells by ionic liquid modification (IL-E-CAT)

Date du début: 1 mai 2016, Date de fin: 30 avr. 2021,

The commercialization of low temperature fuel cells is restricted by the high cost and low durability of cathode catalysts. Intense efforts have been devoted to tackle this issue by engineering the structure of Pt-based catalysts. Herein, a novel concept towards enhancing the performance of low temperature fuel cell catalysts is proposed, namely by tuning the local active site microenvironment wit ...
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 2

 TERMINÉ 

Magnetic resonance imaging platform for probing fat microstructure (ProFatMRI)

Date du début: 1 avr. 2016, Date de fin: 31 mars 2021,

Metabolic syndrome and osteoporosis are the two metabolic diseases with the highest and most rapidly growing prevalence, transforming them into a major global health and socioeconomic concern. Metabolic syndrome can be diagnosed with established biomarkers, but the selection of optimal prevention strategies for each individual patient is still problematic. Osteoporosis can be treated, but its curr ...
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 2

 TERMINÉ 

TRANSATLANTIC TRADE AND INVESTMENT PARTNERSHIP-INTERNATIONAL TRAINING NETWORK (TTIP-ITN)

Date du début: 1 avr. 2017, Date de fin: 31 mars 2021,

The EU currently is negotiating a controversial Transatlantic Trade and Investment Partnership (TTIP) agreement with the USA, the main features of which will be the abolition of tariffs, the reduction of non-tariff barriers to trade between the EU and the USA and the introduction of a dispute settlement mechanism. The objective of the proposed TTIP Innovative Training Network (TTIP-ITN) is to fost ...
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 11

 TERMINÉ 

Science and Innovation with thunderstorms (SAINT)

Date du début: 1 mars 2017, Date de fin: 28 févr. 2021,

Lightning is an extremely energetic electric discharge process in our atmosphere. It significantly affects the concentration of greenhouse gases and it threatens electrical and electronic devices, in particular, when placed on elevated structures like wind turbines or aircraft, and when these structures are built with modern composite materials with inherently low electric conductivity. In additio ...
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 10

 TERMINÉ 

Next-generation in vivo models for improved pancreatic cancer therapies (PanCaT)

Date du début: 1 févr. 2016, Date de fin: 31 janv. 2021,

Maintenance and drug resistance of pancreatic ductal adenocarcioma (PDAC) depends on cancer cell intrinsic mechanisms and a stroma that supports tumor growth. Mouse models of human PDAC have provided important insights into the evolution of this highly lethal tumor, but there are no models that allow secondary genetic manipulation of autochthonous tumors, the tumor microenvironment or the metastat ...
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 2

 TERMINÉ 

Surface Heat Exchangers For Aero Engines 2 (SHEFAE 2)

Date du début: 1 févr. 2016, Date de fin: 31 janv. 2021,

The Project aim is to develop and demonstrate lighter integrated heat exchanger systems for the turbofan engine. Currently in turbofan engines heat exchangers are used to cool the oil that is supplied to the bearing chambers and generators. They contribute to achieving the best engine performance by maintaining oil and fuel temperatures within defined limits. In the future, extensive use of heat e ...
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 3

 TERMINÉ 

Collective effects and optomechanics in ultra-cold matter (ColOpt)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The network “Collective effects and optomechanics in ultra-cold matter” (ColOpt) will train early-stage researchers (ESR) in fundamental science and applications in the areas of cold atom and quantum physics, optical technologies and complexity science to promote European competiveness in emergent quantum technologies. It consists of nine academic nodes and three companies from six European countr ...
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 13

 TERMINÉ 

Combinatorics of Networks and Computation (CONNECT)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

"Networks are present in our lives in numerous different environments: to name just a few, networks can model social relationships, they can model the Internet and links between web pages, they might model the spread of a virus infection between people, and they might represent computer processors/sensors that have to exchange information.This project aims to obtain new insights into the behaviour ...
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 8

 TERMINÉ 

SPIDIA for Personalized Medicine - Standardisation of generic Pre-analytical procedures for In-vitro DIAgnostics for Personalized Medicine (SPIDIA4P)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Molecular in vitro diagnostics and biomedical research have allowed great progress in personalised medicine but further progress is limited by insufficient guidelines for pre-analytical workflow steps (sample collection, preservation, storage, transport, processing etc.) as well as by insufficient quality assurance of diagnostic practice. This allows using compromised patients’ samples with post c ...
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 21

 TERMINÉ 

Overcoming the Limits of Diffraction with Superresolution Lighting on a Chip (ChipScope)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The physical laws of diffraction generally limit the spatial resolution of optical systems, being about 200 nm for light in the visible range. Within ChipScope we want to overcome this limit by developing the scientific and technological basis for a completely new approach to optical superresolution, based on semiconductor nano Light Emitting Diode (nanoLED) arrays with individual pixel operation. ...
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 7

 TERMINÉ 

SiliconLaser (SiLAS)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Our research aims to revolutionize the electronics industry by adding intra-chip and chip-to-chip communication at the speed of light, offering a significantly reduced energy consumption. Cubic crystal phase SiGe is known to be great for electronics. We propose to develop hexagonal crystal phase SiGe (Hex-SiGe) which features a direct bandgap and will add photonic capabilities to electronics. Dire ...
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 6

 TERMINÉ 

An Artificial Leaf: a photo-electro-catalytic cell from earth-abundant materials for sustainable solar production of CO2-based chemicals and fuels (A-LEAF)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

A novel concept for a photo-electro-catalytic (PEC) cell able to directly convert water and CO2 into fuels and chemicals (CO2 reduction) and oxygen (water oxidation) using exclusively solar energy will be designed, built, validated, and optimized. The cell will be constructed from cheap multifunction photo-electrodes able to transform sun irradiation into an electrochemical potential difference (e ...
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 15

 TERMINÉ 

“In Vivo Click PET Imaging Agents”: Improving clinical companion diagnostics (Click-It)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Companion diagnostics are crucial for drug development and disease management with regard to patient selection, therapy planning and monitoring. Nanomedicines such as antibodies have been proven to be optimal disease-targeting agents because they generally exhibit superior target uptake and retention. However, to date, nuclear imaging of nanomedicines has been limited to the use of long-lived isot ...
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 6

 TERMINÉ 

Scanning probe microscopies for nanoscale fast, tomographic and composition imaging (SPM2.0)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Advanced Microscopy techniques are widely recognized as one of the pillars onto which the research and manufacture of Nanotechnology based products is sustained. At present, the greatest challenge faced by these techniques is the realization of fast and non-destructive tomographic images with chemical composition sensitivity and with sub-10 nm spatial resolution, in both organic and inorganic mate ...
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 10

 TERMINÉ 

European Network on Anti-Cancer Immuno-Therapy Improvement by modification of CAR and TCR Interactions and Nanoscale Geometry (EN_ACTI2NG)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The EN-ACTI2NG program (European Network on Anti-Cancer Immuno-Therapy Improvement by modification of CAR and TCR Interactions and Nanoscale Geometry) emanates from the recent clinical evidence that T cells expressing engineered tumor-specific immune receptors can eradicate certain tumors that do not respond to conventional treatment. To obtain T cells with reactivity to a wider array of tumors an ...
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 11

 TERMINÉ 

Novel Quantum Emitters monolithically grown on Si, Ge and III-V substrates (4PHOTON)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

We propose to forge a partnership between the leading European groups working on the next generation of solid state quantum emitters based on novel growth methods such as Droplet Epitaxy. Future, practical Nano-photonics and Quantum Circuits applications demand semiconductor quantum dots that can be grown on substrates with different lattice parameters (Si, Ge, GaAs), different substrate orientati ...
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 11

 TERMINÉ 

Open transPREcision COMPuting (OPRECOMP)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Guaranteed numerical precision of each elementary step in a complex computation has been the mainstay of traditional computing systems for many years. This era, fueled by Moore's law and the constant exponential improvement in computing efficiency, is at its twilight: from tiny nodes of the Internet-of-Things, to large HPC computing centers, sub-picoJoule/operation energy efficiency is essential f ...
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 10

 TERMINÉ 

Synthetic bacterial lipid rafts to optimize industrial bioprocesses (Rafts4Biotech)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Genetic tractability of bacterial cells allows generating synthetic microbial chassis platforms (SMCPs) with remarkable biotechnological applications but their functionality currently faces important off-genome limitations due to deficient protein-protein interactions, unfavorable protein stoichiometry or generation of toxic intermediates that ultimately compromise the industrial production proces ...
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 13

 TERMINÉ 

Quantum Information Access and Retrieval Theory (QUARTZ)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Quantum Information Access and Retrieval TheoryWe aim to establish an European Training Network (ETN) on QUantum information Access and Retrieval Theory (QUARTZ). Towards a new approach to Information Access and Retrieval (IAR) addressing the challenges of the dynamic and multimodal nature of the data and user interaction context, QUARTZ aims to educate its Early Stage Researchers (ESRs) to adopt ...
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 7

 TERMINÉ 

Hybrid Optomechanical Technologies (HOT)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The hybrid optomechanical technologies (HOT) consortium will lay the foundation for a new generation of devices, which connect, or indeed contain, several platforms at the nanoscale in a single “hybrid” system. As hybrid interfaces they will allow to harness the unique advantages of each subsystem within a nano-scale footprint, while as integrated hybrid devices they will enable entirely novel fun ...
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 17

 TERMINÉ 

Small vessel diseases in a mechanistic perspective: Targets for InterventionAffected pathways and mechanistic exploitation for prevention of stroke and dementia (SVDs-at-target)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Stroke and dementia rank among the most pressing health issues in Europe. Cerebral small vessel diseases (SVDs) have emerged as a central link between these two major co-morbidities. SVDs account for more than 30% of strokes and at least 40% of dementia cases. They encounter multiple distinct diseases that can be separated based on their underlying genetic defects, risk factors, and clinical prese ...
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 14

 TERMINÉ 

Analytical and Characterisation Excellence in nanomaterial risk assessment: A tiered approach (ACEnano)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2020,

An increasing number of nanomaterials (NMs) are entering the market in every day products spanning from health care and leisure to electronics, cosmetics and foodstuff. Nanotechnology is a truly enabling technology, with unlimited potential for innovation. However, the novelty in properties and forms of NMs makes the development of a well-founded and robust legislative framework to ensure safe dev ...
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 27

 TERMINÉ 

PlantHUB - Boosting technology transfer and responsible research and innovation (RRI) in plant sciences (PlantHUB)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2020,

In PlantHUB will capture the academic, industrial and regulatory expertise from 5 world-class universities, 1 public research organisation, 1 governmental organization, 8 enterprises including 5 SMEs to train 10 ESRs in skills and competencies necessary to apply responsible research and innovation (RRI) in the area of plant breeding and production. We wish to address the demand of RRI leadership i ...
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 10

 TERMINÉ 

Goal-based Open-ended Autonomous Learning Robots (GOAL-Robots)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,

This project aims to develop a new paradigm to build open-ended learning robots called `Goal-based Open-ended Autonomous Learning' (GOAL). GOAL rests upon two key insights. First, to exhibit an autonomous open-ended learning process, robots should be able to self-generate goals, and hence tasks to practice. Second, new learning algorithms can leverage self-generated goals to dramatically accelerat ...
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 5

 TERMINÉ 

An e-infrastructure for software, training and consultancy in simulation and modelling (E-CAM)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2020,

E-CAM will create, develop and sustain a European infrastructure for computational science applied to simulation and modelling of materials and of biological processes of industrial and societal importance. Building on the already significant network of 15 CECAM centres across Europe and the PRACE initiative, it will create a distributed, sustainable centre for simulation and modelling at and acro ...
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 18

 TERMINÉ 

OMT - Optomechanical Technologies (OMT)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2020,

The proposed project is built on the successful training and research experience of the leading European research groups working in the field of cavity optomechanics. Our ENT unites a total of 14 leading groups in the field, of which two are major industrial players that utilize MEMS and NEMS - Bosch and IBM. The main goal of the project is to exploit optomechanical interactions in views of novel ...
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 14

 TERMINÉ 

Alternative models and robust decision-making for future forest management (ALTERFOR)

Date du début: 1 avr. 2016, Date de fin: 30 sept. 2020,

European forests are expected to provide a broad range of ecosystem services (ES). This capacity is however threatened by the uncertainties of climate change, the complex dynamics of evolving global markets and the pressures for increased use of bioenergy. Such challenges cannot be effectively addressed with an uncritical regional or national commitment to traditional forest management models (FMM ...
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 21

 TERMINÉ 

A DECentralIzed management Scheme for Innovative Valorization of urban biowastE (DECISIVE)

Date du début: 1 sept. 2016, Date de fin: 31 août 2020,

The growing attractiveness of cities leads to increasing population, thus rising energetic and food demands in urban areas. This makes urban waste management increasingly challenging, both in terms of logistics and environmental or health impacts. To decrease the cities’ environmental impacts and to contribute to a better resilience of urban areas towards energy or food supply crisis, waste manage ...
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 13

 TERMINÉ 

REPAiR - REsource Management in Peri-urban AReas: Going Beyond Urban Metabolism (REPAiR)

Date du début: 1 sept. 2016, Date de fin: 31 août 2020,

A shift towards a more circular economy is crucial to achieve more sustainable and inclusive growth. Our objective is to provide local and regional authorities with an innovative transdisciplinary open source geodesign decision support environment (GDSE) developed and implemented in living labs in six metropolitan areas. The GDSE allows creating integrated, place-based eco-innovative spatial devel ...
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 18

 TERMINÉ 

European Training Network for the sustainable, zero-waste valorisation of (critical) metal containing industrial process residues (SOCRATES)

Date du début: 1 sept. 2016, Date de fin: 31 août 2020,

Unlike China, Russia or South Africa, the EU-28 Member States are not in the fortunate position of having vast, easily accessible ore deposits containing valuable metals. However, Europe does have large quantities of secondary industrial residues (tailings, sludges, slags and ashes) that contain sig¬nificant concentrations of both critical and economically important metals. The Euro¬pean Training ...
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 8

 TERMINÉ 

Demonstration of solvent and resin production from lignocellulosic biomass via the platform chemical levulinic acid (GreenSolRes)

Date du début: 1 sept. 2016, Date de fin: 31 août 2020,

The GreenSolRes-Project demonstrates the levulinic acid value chain of lignocellulosic feedstocks to high-value products in a 3-step approach on TRL 6 to 7: First, the feedstock of GFBs existing demo plant in Caserta is shifted to lignocellulosic residues or wastes by implementation of a char separation unit and a boiler to cover the process energy demand. A new product separation unit enables mor ...
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 7

 TERMINÉ 

Light induced spatially EXact and genetically encoded labeling of immune cells for monitoring of lOng Distance and Ultra-compartment Shuttling during autoimmunity and chronic inflammation (EXODUS)

Date du début: 1 sept. 2015, Date de fin: 31 août 2020,

The incidence of autoimmune diseases including multiple sclerosis is dramatically increasing. While there is a genetically defined “bedrock” susceptibility to develop T cell mediated autoimmunity, environmental cues likely determine the threshold for disease development. Yet, little is known on how environmental cues sensed at body/environment interfaces are translated into immunopathology in dist ...
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 2