Defects in the primary metabolic functions of mitochondria, the cell’s‘power-plants’, underlie a diverse range of human pathologies, includingrare neuromuscular syndromes, many cases of common multifactorialdiseases (e.g epilepsy, deafness, diabetes), neurodegenerativeconditions such as Parkinson’s disease (PD), and devastating metabolicdisorders of infancy. Mitochondrial dysfunction is also a maj ...