3 projets européens trouvés
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TERMINÉ
More Medicines for Tuberculosis (MM4TB)
Date du début: 1 févr. 2011, Date de fin: 31 juil. 2016,
The More Medicines for Tuberculosis (MM4TB) consortium evolved from the highly successful FP6 project, New Medicines for TB (NM4TB), that delivered a candidate drug for clinical development two years ahead of schedule. Building on these firm foundations and exploiting its proprietary pharmacophores, MM4TB will continue to develop new drugs for TB treatment. An integrated approach will be impleme ...
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27
Participants partenaires
TERMINÉ
Host target identification of anti-virulence drugs (TARGID)
Date du début: 1 janv. 2014, Date de fin: 31 déc. 2015,
While short course chemotherapy for drug-susceptible tuberculosis (TB) remains effective, it is relatively inefficient by modern pharmaceutical standards and universally menaced by the dissemination of multidrug-resistant (MDR), extensively drug-resistant (XDR) strains of Mycobacterium tuberculosis (M.tb) and synergy with the HIV/AIDS pandemic. Since one third of the world’s population is latently ...
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1
Participant partenaire
TERMINÉ
"Exploring decaprenyl-phosphoryl ribose epimerase (DprE1) as a validated target for TB drug discovery: Assay development, high-throughput screening and search for novel DprE1 inhibitor scaffolds" (DPRETB)
Date du début: 1 mai 2010, Date de fin: 30 avr. 2012,
...d their anti-mycobacterial activity. This work will be performed at EPFL, in a close collaboration between the Global Health Institute and the Institute of Chemical Sciences and Engineering, in Prof. Stewart Cole and Prof. Paul Dyson’s laboratories, respectively."
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