4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Adverse Immune Signatures and their Prevention in Corneal Transplantation (VISICORT)
Date du début: 1 avr. 2014, Date de fin: 31 mars 2019,
"Immune system response is the most complex barrier to long-term success of tissue transplants/implants from allogeneic and bio-artificial sources. While newly developed tissue transplant procedures are not yet performed frequently enough for robust analysis of adverse immune responses in humans, corneal transplantation (CT) is a well-established allogeneic tissue transplant with >100,000 full- an ...
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12
Participants partenaires
TERMINÉ
MEsenchymal stem cells to Reduce Liver INflammation (MERLIN)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,
"Prevalence of liver disease is c6% (29 million people) in the EU with mortality rates from chronic liver diseases estimated at 14.3 per 100.000 in the EU-25 in 2004. Most liver diseases have a significant inflammatory component that underpins liver damage and fibrogenesis, yet current therapies have limited effectiveness. Safe novel anti-inflammatory therapies would satisfy a large unmet need for ...
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9
Participants partenaires
TERMINÉ
Decision-making within cells and differentiation entity therapies (DECIDE)
Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,
"Our ITN has both scientific and therapeutic targets. Research in Work Package 1 (WP1) aims to advance understanding of normal blood cell development and why primitive cells fail to differentiate in acute myeloid leukaemia (AML). Research in WP2 will use the information gained from WP1 to develop ways of alleviating the differentiation block in AML and so deliver new agents for use in differentiat ...
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8
Participants partenaires
TERMINÉ
Repair of Diabetic Damage by Stromal Cell Administration (REDDSTAR)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2016,
50 million diabetic EU citizens are using approved anti-diabetic agents to control their glycaemia. However, suboptimal glycemic control leads to 6 progressive diabetic complications, namely: nephropathy, retinopathy, cardiomyopathy, neuropathy and foot ulceration. In 2010, 11% of EU adult deaths (634,000) were caused by diabetic complications. These distinct disorders have few effective medicines ...
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