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 TERMINÉ 
Fifteen years ago it was widely believed that asthma was an allergic/atopic disease caused by allergen exposure in infancy; this produced atopic sensitization and continued exposure resulted in eosinophilic airways inflammation, bronchial hyper-responsiveness and reversible airflow obstruction. It is now clear that this model is at best incomplete. Less than one-half of asthma cases involve allerg ...
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 6

 TERMINÉ 

Combatting Bacterial Resistance in Europe - Carbapenem Resistance (COMBACTE-CARE)

Date du début: 1 mars 2015, Date de fin: 28 févr. 2020,

Multi-drug resistant Gram-negative bacteria (MDR-GNB): the ultimate challenge!Antibiotic resistance is a global public health concern recently elevated to the top three threats identified by the WHO, and subject of numerous national and international government activities. Although focused strategies have beneficially influenced infection rates due to methicillin resistant Staphylococcus aureus (M ...
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 23

 TERMINÉ 

European Gram Negative Antibacterial Engine (ENABLE)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2020,

The intensive use and misuse of antibiotics has resulted in some level of antibiotic resistance in essentially all human bacterial pathogens. There is a growing concern that the loss of therapeutic options will present us with a post-antibiotic era where present and future medical advances are negated. Resistant bacteria dramatically reduce the possibilities of treating infections effectively, a ...
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 42

 TERMINÉ 
Vancomycin is the critically important antibiotic to treat neonatal Late Onset Sepsis (LOS) due to Gram positive bacteria in neonates, including Coagulase Negative Staphylococci (CoNS) and Staphylococcus aureus. These organisms also create biofilms which are extremely resistant to antibiotics. The increased incidence of LOS due to bacteria such as CoNS and MRSA in NICUs has led to a marked increas ...
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 14

 TERMINÉ 

Widening Access to Virtual Educational Scenarios

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2018,

Each area of professional competency faces its own challenges in providing relevant training before workplace practice. In public service and industry, too much is expected of students learning from their apprenticeship phase, compromising reliability or safety. Trainees lack opportunities to practise applying “inert” knowledge to a real task context, while in a risk-free environment. In response, ...
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 6

 TERMINÉ 

Eliciting Mucosal Immunity to Tuberculosis (EMI-TB)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

Tuberculosis (TB) is a global health problem, killing 1.5 million of people every year. The only currently available vaccine, Mycobacterium bovis BCG, is effective against severe childhood forms, but it demonstrates a variable efficacy against the pulmonary form of TB in adults. Many of these adult TB cases result from the reactivation of an initially controlled, latent Mycobacterium tuberculosis ...
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 15

 TERMINÉ 
Smoking is the largest avoidable cause of preventable morbidity worldwide. It causes most of the cases of lung cancer and chronic obstructive pulmonary disease (COPD) and contributes to the development of other lung diseases. The control of smoking is considered as a highly important intervention for the prevention of lung diseases. Tobacco consumption is highly influenced by socioeconomic factors ...
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 14

 TERMINÉ 

Training Against Medical Error

Date du début: 15 oct. 2015, Date de fin: 14 oct. 2018,

The overall objective of this project is to introduce innovative pedagogy methods that will provide training for students against medical error (TAME). TAME will innovate curricula towards teaching and learning in safe environment and closer to the needs of the real practice, where medical errors occur. With achievement of TAME’s objectives, a great need for the changes in the national healthcare ...
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 10

 TERMINÉ 

Improving education for sustainable development through development of school culture

Date du début: 1 sept. 2016, Date de fin: 31 août 2018,

...ine education as a vital tool in developing ESD to a global phenomena. In Europe this has been taken into account in curriculums widely but too often ESD education is considered as an ‘add on’. Instead it should be a natural and essential part of school culture in order to educate students towards a sustainable way of life. In this project - the different dimensions of school culture are explored ...
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 8

 TERMINÉ 
The PHOCNOSIS project aims at the development and the preclinical validation of a nanotechnology-based handheld point-of-care testing (POCT) analysis device for its application in the early diagnosis of cardiovascular diseases (CVD). The diagnosis will be carried out by means of the fast (
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 10

 TERMINÉ 
Biopharmaceutical proteins are typically produced in cultivated mammalian cells, a costly process with limited scalability. Thus products such as monoclonal antibodies are very expensive and often beyond the reach of the world’s poor. The problem is compounded by the fact that important strategies for preventing diseases such as HIV and rabies typically involve large doses of multiple antibodies a ...
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 2

 TERMINÉ 

International Business Skills for the Vienna Business School Plus

Date du début: 1 nov. 2015, Date de fin: 31 oct. 2017,

This mobility project is based on a cooperation of four partner institutions in three European countries, Austria, the UK and Malta. The aim of the project is to improve the employability of the Austrian participants who will acquire additional qualifications in the course of a three week work experience programme in the UK and in Malta. The forty beneficiaries are students of the Vienna Business ...
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 4

 TERMINÉ 
Drug development in TB requires new integrated methods to transition the novel combination regimens needed to shorten first-line therapy and combat multi-drug resistance. Although new agents are emerging, the path to registration of such regimens remains uncertain while capacity for pivotal trials is limited. Selection and optimization of drug combinations for development depends on preclinical sy ...
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 23

 TERMINÉ 

Higher education student and staff mobility project

Date du début: 1 juin 2016, Date de fin: 30 sept. 2017,

This is a higher education student and staff mobility project, please consult the website of the organisation to obtain additional details.
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 1

 TERMINÉ 

Advanced Immunization Technologies (ADITEC)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2017,

Vaccines so far have been developed mostly by following an empiric approach. To prevent and possibly cure unresolved and emerging infectious diseases we need to fully exploit the potential of the human immune system. Progress in science and technology makes it possible to achieve what was previously deemed impossible. The scope of this project is to produce knowledge necessary to develop novel and ...
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 53

 TERMINÉ 

Medical Curriculum Innovations

Date du début: 1 sept. 2015, Date de fin: 31 août 2017,

The need for standardized curriculum particularly in medical education is indispensable. Today a comprehensive platform that would cover all necessary instruments for easy in-depth curriculum management is still missing. For any platform to achieve these goals, it is essential that data standards are used to enable the systems to communicate across organizations and implementations. The intention ...
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 4

 TERMINÉ 

Global Research in Paediatrics (GRiP)

Date du début: 1 janv. 2011, Date de fin: 30 juin 2017,

Paediatric drugs (PD) lack appropriate testing. Most drugs have inadequate information about dosing regimen, dose adjustment and how to administer them. These are longstanding problems that unquestionably require concerted efforts at the international level. Both the US and the EU have introduced paediatric legislation that facilitates participation of children in research and pharmaceutical innov ...
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 24

 TERMINÉ 

Vielfalt und Identität

Date du début: 1 juin 2015, Date de fin: 31 mai 2017,

...lities for Learners (A), as well as professionals (B) in vocational training.A) LearnersIn 2015, the Leonardo-Project “Diversity and Identity“, organized by the Käthe Kollwitz School, offers 17 students, attending a professional training to become qualified educators, the chance for a professional training abroad.The professional college for qualifying educators is a branch of the Käthe Kollwitz S ...
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 10

 TERMINÉ 

Biomarkers For Enhanced Vaccine Safety (BIOVACSAFE)

Date du début: 1 mars 2012, Date de fin: 31 déc. 2016,

BioVacSafe is a concise consortium of selected academic, public, and SME participants used to co-working in industry-led projects, organised into focused Activity Cores to generate knowledge and tools to benchmark licensed vaccine reactogenicity, and create practical and generalizable guidelines and techniques to enhance immunosafety of novel vaccines from pre-development to post-marketing surveil ...
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 24

 TERMINÉ 
The project „Innovative methods of using payment instruments in a economic activities of a company” is a mobility project implemented by Liceul Tehnologic Bratianu, having as host partner St.Georgess Clubclass School of English Ltd, from Worthing, Great Britain. The purpose of this project is the training through direct participation to an internship stage in the domain of using the payment tools, ...
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 2

 TERMINÉ 
...ly damaged and usually die but cellular loss can occur hours and days thereafter. These diseases cause massive morbidity and mortality and tremendous economic and societal burden, especially ischemic stroke, which is a leading cause of death and disability with no effective treatment to promote recovery. The brain responds to a stroke, i.e., occlusion of a cerebral artery, with an inflammatory pro ...
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 10

 TERMINÉ 
The project “the acquisition of innovative competences for the practical use of the commerce effects” was born from the necessity to offer to a number of 80 students from initial vocational education, the chance to take part to a practice internship in real conditions of work in the financial – accountancy department of a British company. At the end of the practice internships, it will be ensured ...
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 2

 TERMINÉ 

Higher education student and staff mobility project

Date du début: 1 juin 2015, Date de fin: 30 sept. 2016,

This is a higher education student and staff mobility project, please consult the website of the organisation to obtain additional details.
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 1

 TERMINÉ 

Clinical reasoning skills enhancements with the use of simulations and algorithms

Date du début: 1 sept. 2014, Date de fin: 31 août 2016,

...odules in single discipline biosciences, bear little relationship to eventual learner needs for clinical practice. Practitioners act by synthesizing a range of relevant information, identifying and testing solutions. Developing competence in this crucial process requires an approach that differs from traditional teaching, where students are recipients of information. Problem-Based Learning (PBL) i ...
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 3

 TERMINÉ 

CRECIENDO EN EUROPA I

Date du début: 1 août 2014, Date de fin: 31 juil. 2016,

...a Consortium and submit this European mobility program proposal. At the origin of this proposal is our concern for the labour situation that suffer our young people nowadays, those that are actually studying and those who have recently finished their studies. Besides, their situation is worsened by the shortage of entrepreneurship in our city. 79 young students have participated in this project. ...
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 39

 TERMINÉ 
Outbreaks of clinical infections affect many thousands of patients in Europe yearly. The present effective treatment for infections is large doses of systemically applied drugs. There is a high risk of recurring infections and biofilm formation for patients dependent on long term in-dwelling catheters and the extended dependency on antibiotics result in clinical drug resistance. We present a new t ...
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 7

 TERMINÉ 

Semantic Data Platform for Healthcare (SEMCARE)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2015,

...ical trials. The platform will identify patient cohorts based on patient-level criteria (e.g. age, gender, diagnosis, indication, symptoms, lab results) scattered in heterogeneous clinical data. As most of patient-level data is unstructured, language technologies are necessary to extract and exploit the relevant data. Our platform combines the power of full text search with text analytics and sema ...
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 5

 TERMINÉ 

Cutaneous and Mucosal HIV Vaccination (CUT'HIVAC)

Date du début: 1 janv. 2010, Date de fin: 31 déc. 2015,

Despite significant effort over the past decade to design and implement new vaccines strategies against HIV, no one has met its promise to prevent infection and/or to reduce viral load until reaching eradication of the HIV reservoir. To reach this goal, a translational research is critical to propose innovative approaches for an HIV vaccine enhancing broadly cross-reactive mucosal, humoral and cel ...
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 18

 TERMINÉ 
For decades, researchers have used small mammals to study the underlying processes of human disease and potential therapies for such ailments. Current strategies for measuring disease progression and/or drug effect usually involve groups of animals being killed at multiple time points for post-mortem tissue analysis. Recently, transgenic strains of mice have been created in which light-emitting lu ...
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 3

 TERMINÉ 

TRANSLATIONAL RESEARCH AND PATIENT SAFETY IN EUROPE (TRANSFoRm)

Date du début: 1 mars 2010, Date de fin: 30 nov. 2015,

...for the integration of Primary Care clinical and research activities, to support patient safety and clinical research via:1.\tRich capture of clinical data, including symptoms and signs rather than just a single diagnosis. A generic, dynamic interface, integrated with electronic health records (EHR), will facilitate both diagnostic decision support and identification of patients eligible for resea ...
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 25

 TERMINÉ 

The European Network for Translational Research in Atrial Fibrillation (EUTRAF)

Date du début: 1 nov. 2010, Date de fin: 31 oct. 2015,

"The initiation and perpetuation of atrial fibrillation (AF) can be regarded as a complication of a progressive transformation of the structure and functional properties of the atria. This transformation is the result of complex and multiple changes at the molecular, cellular and organ levels which interact to form the basis for proarrhythmic mechanisms in AF. Numerous individual and environmental ...
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 20

 TERMINÉ 
...e elimination of malaria in different countries depends critically on provision of effective antimalarials and further that these antimalarials are used appropriately in individual patients. Drug resistance is a major threat to malaria control and has important global public health implications. Over the past decades the genetic bases for resistance to most of the antimalarial classes currently in ...
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 4

 TERMINÉ 

Combined Highly Active Anti-retroviral Microbicides (CHAARM)

Date du début: 1 janv. 2010, Date de fin: 30 juin 2015,

This proposal is for a large scale collaborative project in which we propose both to develop novel microbicides directed against new intracellular targets and to investigate novel combinations of highly active anti-retroviral drugs which may be particularly effective as microbicides. Combinations may enhance efficacy but equally importantly will increase the genetic barrier to the development of r ...
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 34

 TERMINÉ 
Previous studies have demonstrated the high frequency of bacterial sepsis in neonates and infants admitted to neonatal intensive care unit (NICU), often associated with serious complications or death. Many pathogens capable of causing nosocomial bacterial sepsis in neonates and young infants have developed resistance to the antibiotics considered of choice for treatment. Meropenem is an antibiotic ...
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 12

 TERMINÉ 

Knowledge exchange in processing and analysis of multi-omic data (KEPAMOD)

Date du début: 1 avr. 2012, Date de fin: 31 mars 2015,

...h experiments are referred to as omic data, to indicate their genome-wide coverage. Advances in biotechnology have resulted in the possibility to obtain a growing variety of omic datasets. However, most computational and algorithmic efforts have been directed at mining data from each of these molecular levels (genomic, transcriptomic, etc.) separately and combining the results in order to explore ...
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 4

 TERMINÉ 
The main purpose of RESCAP-MED is to enhance the non-communicable diseases (NCDs) research landscape in southern and eastern Mediterranean countries by (a) strengthening capacity in a set of disciplines most relevant to improving public health and reducing health inequalities, and (b) enhancing networking, cooperation, and collaboration between researchers in the Mediterranean region. The main co ...
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 12

 TERMINÉ 

EUROpean consortium on NEUTralising antibodies using gp41 (EURONEUT-41)

Date du début: 1 janv. 2008, Date de fin: 31 mars 2014,

There is now an increasingly solid body of scientific evidence which demonstrates that the binding of small molecular weight compounds, peptides and antibodies (Abs) to fusion-intermediate conformations of gp41 leads to an inhibition of HIV cell entry. The principal aim of this project is to exploit this information by establishing a platform where gp41-derived vaccine candidates will be designed ...
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 19

 TERMINÉ 
...ion has never been better. However, serious public health problems remain, which cannot be ignored including high levels of premature death due to cardiovascular diseases. Thus, new preventive, diagnostic and therapeutic strategies against atherosclerotic cardiovascular diseases are needed. The atherosclerotic changes of the vascular wall are central in the development of cardiovascular complicat ...
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 19

 TERMINÉ 

Arrhythmogenic potential of drugs (ARITMO)

Date du début: 1 janv. 2010, Date de fin: 30 juin 2013,

...e in the QT interval does not necessarily lead to TdP which further increased the regulatory and clinical difficulties. This proposal will assess the arrhythmogenic potential of antipsychotics, antihistamines and anti-infectives (> 250 compounds). It will fulfill this aim by: reviewing the literature on in-vitro and in-vivo preclinical evidence; conducting in-silico modeling to predict the arrh ...
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 21

 TERMINÉ 
Buruli ulcer disease (BUD), caused by Mycobacterium ulcerans, is a neglected bacterial infection of the poor in remote rural areas, mostly affecting children. BUD, the third most common mycobacterial disease in immunocompetent humans after tuberculosis and leprosy, is most endemic in West Africa, but cases have been reported from more than 30 countries. BUD is a mutilating disease leading to sever ...
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 16