7 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
ATMP GMP Open Access Research Alliance - AGORA (AGORA)
Date du début: 1 sept. 2013, Date de fin: 31 oct. 2015,
We propose an academic & industrial partnership to facilitate safe and effective delivery of new advanced therapy medicines within the framework of the relevant EU regulations which our previous FP7 funded project have identified as creating unanticipated barriers to development of this field. Over 80% of advanced therapy medicines (ATMPs) trials in the EU are academic investigator led and sponsor ...
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8
Participants partenaires
TERMINÉ
Novel immunotherapies for type 1 diabetes (NAIMIT)
Date du début: 1 nov. 2009, Date de fin: 30 avr. 2015,
This proposal will pioneer the concept of tailored interventions with minimal immune system interference in new onset T1DM, leading to beta-cell protection and restoration, based on a solid understanding of the disease pathogenesis. This will enable experimental findings to be adopted for future clinical application. Four work packages are grouped around ‘Reversal of autoimmunity’, in which two ke ...
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15
Participants partenaires
TERMINÉ
Molecular regulation of blood coagulation factor V: from snakes to humans (MoReFV)
Date du début: 1 sept. 2010, Date de fin: 31 août 2014,
The overall goal of this proposal is to provide new information on the molecular mechanisms that regulate the cofactor function of blood coagulation factor V (FV). Shedding light on these processes may provide a framework for developing novel strategies for prevention and treatment in cases of disregulation of the blood coagulation response. This is a uniquely complex process that protects organis ...
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1
Participant partenaire
TERMINÉ
Identification of Mechanisms Correlating with Susceptibility for Avian Influenza (IMECS)
Date du début: 1 avr. 2008, Date de fin: 31 déc. 2012,
IMECS is a proposal of the FLUSECURE network aimed at combating the threat of new and re-emerging forms of highly pathogenic influenza in its first stages of a disease by identifying mechanisms of protection that are essential for a solid immune response to avian influenza. IMECS is uniquely featured by correlating research in humans directly to protection from influenza. The IMECS initiative was ...
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8
Participants partenaires
TERMINÉ
Dissection of T cell cosignaling and development of vaccination strategies to cytomegalovirus (Vaccination to CMV)
Date du début: 1 oct. 2010, Date de fin: 30 sept. 2012,
Cytomegalovirus (CMV, a β-herpesvirus) infects the majority of the world’s population, establishing a lifelong infection. This infection is largely asymptomatic in immune competent hosts, but causes severe disease in immunocompromised neonates and adults. In healthy persistently infected individuals huge numbers of CMV-specific T cells accumulate over time (i.e. “memory inflation”), a process rece ...
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1
Participant partenaire
TERMINÉ
Set up and comparison of multiple stem cell approaches for kidney repair (STAR-T REK)
Date du début: 1 nov. 2008, Date de fin: 31 oct. 2011,
"With the increasing rate of end-stage renal failure and limited alternatives for its treatment, potential regenerative approaches for kidney damages are urgently needed. Because of the complexity of the organ, the development of stem cell therapies for kidney is still in its infancy. Identifying which cell types are capable of beneficial effects is the critical step required to realize the potent ...
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11
Participants partenaires
TERMINÉ
Stem Cell Expansion - Expansion and engraftment of haematopoietic and mesenchymal stem cells (STEMEXPAND)
Date du début: 1 nov. 2008, Date de fin: 31 oct. 2011,
"Serious disorders of the blood system, particularly malignant blood disorders and genetic diseases can be effectively treated by blood and marrow transplantation. Despite considerable success with this treatment modality during the last decades, lack of suitable donors, engraftment failure and graft versus host disease remain serious problems that need to be addressed. This project aims to addres ...
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