3 projets européens trouvés
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TERMINÉ
Genetics of Resistance to Malaria Parasites in the Mosquito Anopheles gambiae (MALARES)
Date du début: 1 juin 2011, Date de fin: 31 mai 2017,
Anopheles gambiae mosquitoes are major vectors of Plasmodium falciparum, a protozoan parasite that causes the most severe form of human malaria in Africa. With an estimated 250 million infected people every year and another 3.3 billion at risk, malaria remains one of the biggest scourges of humanity. One of the promising approaches to fight malaria is the control of vector competence that determin ...
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2
Participants partenaires
TERMINÉ
Transcriptional regulation of IL-9-producing CD4 T cells: use in cancer immunotherapy (T9CAN)
Date du début: 1 avr. 2012, Date de fin: 31 mars 2016,
"Differentiation of naïve CD4 T cells in presence of TGF-beta and IL-4 has led to the identification of a novel IL-9-secreting-population of CD4 T cells, Th9 cells, which are characterized by their potent IL-9 release and their ability to induce proinflammatory responses in vivo. Co-transfer of in vitro differentiated Th9 cells from naïve T cells along with effector cells increase the severity of ...
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1
Participant partenaire
TERMINÉ
EUROpean consortium on NEUTralising antibodies using gp41 (EURONEUT-41)
Date du début: 1 janv. 2008, Date de fin: 31 mars 2014,
There is now an increasingly solid body of scientific evidence which demonstrates that the binding of small molecular weight compounds, peptides and antibodies (Abs) to fusion-intermediate conformations of gp41 leads to an inhibition of HIV cell entry. The principal aim of this project is to exploit this information by establishing a platform where gp41-derived vaccine candidates will be designed ...
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