9 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Exploring brain intracellular space using diffusion-weighted NMR spectroscopy in vivo (INCELL)
Date du début: 1 déc. 2013, Date de fin: 30 nov. 2018,
"Alterations of the intracellular space, including intracellular protein accumulation, organelle and cytoskeleton dislocation, and modifications in cell shape, are an early hallmark of many neurodegenerative processes. The ability to assess and quantify these alterations non-invasively would be of tremendous interest, not only in a clinical context, but also for preclinical research. However, no t ...
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1
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TERMINÉ
Human pluripotent stem cell differentiation, safety and preparation for therapeutic transplantation in Huntington’s disease (Repair-HD)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
This project will tackle the huge complexity of taking stem cell therapies to clinical application for neurodegenerative disease by focusing on selective differentiation of a single neuronal phenotype (medium spiny striatal neuron: MSN) for a single well-defined disease (Huntington’s: HD). Our consortium contains expertise in all elements required to drive this technology to the point of clinical ...
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10
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TERMINÉ
European Autism Interventions - A Multicentre Study for Developing New Medications (EU-AIMS)
Date du début: 1 avr. 2012, Date de fin: 31 mars 2017,
Despite dramatic advances in molecular and imaging technologies, there are currently no effective pharmacological treatments for the core symptoms of autism spectrum disorder (ASD). Major obstructions to this include a lack of aetiologically-driven or pathophysiologically-accurate animal models; an absence of tests that indicate efficacy; and reliance of clinical trials on DSM/ICD10 categories wh ...
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29
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TERMINÉ
Imaging of Neuroinflammation in Neurodegenerative Diseases (INMiND)
Date du début: 1 mars 2012, Date de fin: 28 févr. 2017,
The goal of this proposal (INMiND) is to carry out collaborative research on molecular mechanisms that link neuroinflammation with neurodegeneration in order to identify novel biological targets for activated microglia, which may serve for both diagnostic and therapeutic purposes, and to translate this knowledge into the clinic. The general objectives of INMiND are:(i) to identify novel mechanisms ...
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32
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TERMINÉ
The Human Brain Project (HBP)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,
Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the ...
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116
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TERMINÉ
Automatic detection and monitoring of consciousness (COMONIN)
Date du début: 1 mars 2014, Date de fin: 31 août 2015,
When patients recover from coma, determining their level of consciousness can be difficult, even for an experienced clinician. Our goal is to provide a Consciousness Monitoring Index: a robust method to detect and quantitatively monitor the extent to which a human being is or is not conscious. Using electrodes attached to the scalp, we monitor the electro-encephalographic (EEG) signal which reflec ...
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2
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TERMINÉ
NeuGRID for you: expansion of NeuGRID services and outreach to new user communities (N4U)
Date du début: 1 juil. 2011, Date de fin: 30 avr. 2015,
Unprecedented growth in the accessibility of imaging data of persons with brain diseases has led to the development of computational infrastructures offering scientists access to image databases and e-Science services. FP7 neuGRID is the leading e-Infrastructure where neuroscientists can find core services and resources for brain image analysis. "neuGRID for Users" (N4U) will provide an e-Science ...
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14
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TERMINÉ
Neural correlates of predictive mechanisms in multisensory perception (PredictiveNeuroSens)
Date du début: 1 mars 2010, Date de fin: 28 févr. 2014,
There are many situations in which what we see (hear) is strongly affected by what we hear (see). For instance, in the classic ventriloquism effect, the perceived location of a sound (ventriloquist's speech) is displaced towards the location of a concomitant visual event (puppet). In spite of the implausibility of the situation, our perception is resilient to our conscious knowledge that the puppe ...
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1
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TERMINÉ
Human Brain Project (HBP)
Date du début: 1 mai 2011, Date de fin: 30 avr. 2012,
The human brain can be seen as an immensely powerful, energy efficient, self-learning, self-repairing computer. If we could understand and mimic the way the brain works, we could revolutionize information technology, medicine and society. But to do so we have to bring together everything we know and everything we can learn about the inner workings of the brain's molecules, cells and circuits. The ...
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