5 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
iABC Programme (IABC PROGRAMME)
Date du début: 1 août 2015, Date de fin: 31 juil. 2020,
Cystic Fibrosis (CF) is a common fatal inherited disease with a frequency of 1 in 2500 live births, affecting approximately 36,000 (0.737/10,000) people in the EU. Chronic bacterial pulmonary infection leading to an irreversible decline in lung structure and function is the main cause of mortality and morbidity in patients with CF, with more than 95% of deaths due to respiratory failure. Pseudomon ...
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21
Participants partenaires
TERMINÉ
Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases (PRECISESADS)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,
We concur to the IMI on “Reclassification of SLE, connective tissue diseases and RA” call by presenting a proposal aimed at using the power of OMICs, and bioinformatics to identify new classifications for diseases known to share common pathophysiological mechanisms. Such knowledge has not been applied to individual patients, depriving them from potential benefits in terms of the use of new therape ...
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30
Participants partenaires
TERMINÉ
Biomarkers of renal graft injuries in kidney allograft recipients (BIOMARGIN)
Date du début: 1 mars 2013, Date de fin: 28 févr. 2018,
In renal allograft recipients, 10-year graft survival has not improved over the past decades. Histological examination of graft biopsies has long been the gold standard to confirm graft injuries, but biopsies are invasive and histological grading is not very robust. There is thus a need for robust, non-invasive methods to predict and diagnose acute and chronic graft lesions, to improve patient tre ...
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13
Participants partenaires
TERMINÉ
Natural Killer Cell-Based Anti-Cancer Immunotherapies: Research training in molecular medicine and biotechnology business (NATURIMMUN)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,
"In the research part we will deal with the basic principles of the innate immune defense used to control tumors and viral infections with a focus on NK and NK/T cells, including analysis of NK receptor genomics/epigenetics, gene polymorphisms/disease linkage, differentiation of hitherto unrecognized NK cell subpopulations and novel ligands for NK receptors exposed by tumor and/or virally infected ...
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12
Participants partenaires
TERMINÉ
Individualized Implant Placement (IIP)
Date du début: 1 janv. 2014, Date de fin: 31 déc. 2014,
"The goal of the Proof of Concept (PoC) project is a licensing software (e.g. within a spin-off) that provides a framework to compute a suited (individualized) implant placement for patients: E.g. for hip or knee replacements, during an operation planning phase, a surgeon selects an implant and determines its placement and possible motion range. Since humans are highly individual, factors such as ...
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