4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Proteostasis of aging and stem cells (Proteostasis of hESC)
Date du début: 1 août 2014, Date de fin: 31 juil. 2018,
While it is has long been noted that genome stability is a central function required for survival of stem cells, the role of protein homeostasis (proteostasis) has not been explored. With the asymmetric divisions invoked by stem cells, the passage of damaged proteins to daughter cells can destroy the resulting lineage of cells and possibly accelerate the aging process. Furthermore, the possible re ...
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1
Participant partenaire
TERMINÉ
Epithelial cells in inflammation (EpInflam)
Date du début: 1 mai 2013, Date de fin: 30 avr. 2018,
The cross talk between the host and the microbiota is believed to be the major determinant of health and disease in the gastrointestinal tract. Inflammatory bowel diseases (IBD) are chronic inflammatory conditions of the intestine with unclear aetiology. Deregulation of the cross talk between the intestinal microbiota and the host immune system is considered a main factor contributing to IBD. Geno ...
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1
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TERMINÉ
Tuning the properties of NanoCarbon with Fluorination (NANOCF)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
Low-dimensional carbon structures such as graphene and carbon nanotubes have raised tremendous interest in recent years both from fundamental and technological perspectives. However, the tunability of the density of electronic states of graphene and carbon nanotubes remains a limiting factor for their implementation in modern nanotechnology. It has been recently shown that the energy bandgap of gr ...
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7
Participants partenaires
TERMINÉ
Mitochondrial membrane organization by protein scaffolds and lipid dynamics (MITOSCAFFOLD)
Date du début: 1 avr. 2009, Date de fin: 31 déc. 2014,
Biological membranes are complex structures built up of a multiplicity of membrane lipids and proteins controlling essential cellular processes. This is exemplified by mitochondria, dynamic double-membrane bound organelles, with essential roles in diverse metabolic and cellular signalling pathways. The mitochondrial inner membrane is considered to be the protein richest cellular membrane, whose fu ...
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