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17 projets européens trouvés

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 TERMINÉ 
"High incidence of degenerative skeletal tissue disorders in a progressively aging human population make tissue engineering of cartilage and bone a focus of extensive research. Bone and joint disorders are the most common disease in Europe: more than 100 million European citizens suffer from arthritis and 19 million people have osteoporosis (one of three women and one of eight men are affected). T ...
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 7

 TERMINÉ 

Anti-Parasitic Drug Discovery in Epigenetics (A-PARADDISE)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2017,

This proposal builds on the proven methodology developed in the SEtTReND FP7 project to develop inhibitors of schistosome HME as lead compounds for new drugs. We will employ a target-based strategy for the development of novel drug leads against schistosomiasis, leishmaniasis, Chagas disease and malaria by targeting histone modifying enzymes (HME), in particular those involved in acetylation/deace ...
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 16

 TERMINÉ 
Background:In current drug safety education and training in Europe, an integrative and translational approach is lacking. This shortfall has been identified by EUFEPS. The IMI (‘Strategic Research Agenda’), the FDA and the EMEA have also characterised this fact as a crucial gap in the education and training of scientists evaluating the safety of drug candidates and new medicines. Scope and objecti ...
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 34

 TERMINÉ 
The M C Squared project will design and develop an intelligent digital environment to support stakeholders from creative industries involved in the production of media content for educational purposes to engage in collective forms of creative thinking and working to co-design appropriate digital media. The focus will be on social creativity in the design of digital media intended to enhance creati ...
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 12

 TERMINÉ 

Drug Disease Model Resources (DDMORE)

Date du début: 1 mars 2011, Date de fin: 31 août 2016,

Model based-drug development (MBDD) is accepted as a vital approach in understanding patient risk/benefit and attrition. At the core of MBDD lies Modelling and Simulation (M&S), a technology providing the basis for informed, quantitative decision-making.M&S facilitates the continuous integration of available information related to a drug or disease into constantly-evolving mathematical models capa ...
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 28

 TERMINÉ 

Psychiatric Diagnostic and Prevention Consortium (PSYCHDPC)

Date du début: 1 janv. 2012, Date de fin: 31 juil. 2016,

PsychDPC contains leading European centres in genetics and psychiatry, richly endowed with expertise in both clinical and basic research. The partners bring together state-of-the-art technical facilities, high academic standards as well as established training activities, which will be utilized in concert to maximise the outcome of the project. The primary aim of PsychDPC is to translate data emer ...
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 6

 TERMINÉ 
Treatment resistant schizophrenia (TRS) is the most disabling of all psychiatric illnesses, affecting about 1/3 of patients (~1 million Europeans), a considerable economic and social burden. First-line treatments include atypical (e.g. olanzapine) and typical (e.g. haloperidol) antipsychotics. The original atypical, clozapine, is a final option, and although it is the only antipsychotic shown to b ...
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 11

 TERMINÉ 
Inspection and Maintenance are important aspects when considering the availability of aircraft for revenue flights. Modern airframe design is exploiting new exciting developments in materials and structures to construct ever more efficient air vehicle able to enable ‘smart’ maintenance including self-repair capabilities. The improvement in the aircraft safety by self-healing structures and protect ...
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 10

 TERMINÉ 

New approaches for the targeted therapy of Non-Small Cell Lung Cancer (LUNGTARGET)

Date du début: 1 janv. 2011, Date de fin: 30 juin 2015,

Lung cancer is the most common cancer fatality in Europe (335000 deaths/yr). Non-small cell lung cancer (NSCLC) consists 85% of the cases, with 5 yr survival
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 10

 TERMINÉ 

Functional significance of forest biodiversity in Europe (FunDivEUROPE)

Date du début: 1 oct. 2010, Date de fin: 31 mars 2015,

FunDivEUROPE (FUNctional significance of forest bioDIVersity in EUROPE) proposes to quantify the effects of forest biodiversity on ecosystem function and services in major European forest types in the main bioclimatic regions of Europe. FunDivEUROPE will be based on four scientific platforms and seven cross-cutting Work Packages.The project will combine a global network of tree diversity experimen ...
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 26

 TERMINÉ 
For any strategy aimed to reduce socioeconomic inequities in health in Europe it is vital to tackle the large and widening inequalities in smoking. However, there is only limited evidence on effectiveness of tobacco control policies in terms of reducing inequalities. Especially lacking are evaluations of the effects of policies that have actually been implemented in different European countries. I ...
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 12

 TERMINÉ 
This project analyses tourism development in relation to social policy in Broome, Western Australia. Tourism is the largest and fastest growing industry in the world and therefore a major field in the area of globalization. Social policy is an integral part of this growing market space. The central question is how images of Aboriginal culture and environment change through tourism impact and how t ...
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 1

 TERMINÉ 
In the context of climate change mitigation, technologies for removing the CO2 from the atmosphere are key challenges. The transfer of carbon from the atmosphere into useful carbon deposits is currently one promising option.Transferring biomass to carbon-rich materials with potential mega-scale application is an option to sequester carbon from plant material, taking it out of the short-term carbon ...
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 8

 TERMINÉ 

Next Generation Hybrid Interfaces for Spintronic Applications (HINTS)

Date du début: 1 juin 2011, Date de fin: 31 mai 2014,

The development of conceptually new materials following a “double beyond” trend, that is going “beyond CMOS” with “beyond silicon” materials, is one of the most challenging issues for the next generation of products for Information and Communication applications. Future devices for information processing able to increase the public wealth and occupation require a further material downscaling, toge ...
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 14

 TERMINÉ 

Complex Socio-Technical System in Ambient Intelligence (SOCIONICAL)

Date du début: 1 févr. 2009, Date de fin: 31 janv. 2013,

We will develop Complexity Science based modelling, prediction and simulation methods for large scale socio-technical systems. We focus on the specific example of Ambient Intelligence (AmI) based smart environments. A key component of such environments is the ability to monitor user actions and to adjust its configuration and functionality accordingly. Thus, the system reacts to human behaviour wh ...
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 17

 TERMINÉ 

Schistosoma Epigenetics - Targets, Regulation, New Drugs (SEtTReND)

Date du début: 1 janv. 2010, Date de fin: 31 déc. 2012,

We propose to develop novel drug leads for the therapy of the major human parasitic disease, schistosomiasis, using a holistic approach that will enable us to progress from the cloned target protein to the lead compound and from epigenetic inhibitors to crucial targets. For this, we have chosen to target the histone modifying enzymes (HME); histone deacetylases (HDAC), histone acetyltransferases ( ...
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 9

 TERMINÉ 
Mitochondrial dysfunction is a major hallmark of various neurodegenerative disorders including Alzheimer’s disease, Parkinson’s disease, Huntington’s diseases or Amyotrophic Lateral Sclerosis (ALS). However linking mitochondrial dysfunction to the pathogenesis of some of these diseases still needs to be elucidated. Furthermore, in pathologies where this link is already established, the question re ...
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 19