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 TERMINÉ 

Mechanical control of biological function (MECHANO-CONTROL)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Mechanical forces transmitted through specific molecular bonds drive biological function, and their understanding and control hold an uncharted potential in oncology, regenerative medicine and biomaterial design. However, this potential has not been realised, because it requires developing and integrating disparate technologies to measure and manipulate mechanical and adhesive properties from the ...
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 7

 TERMINÉ 

Transcranial brain stimulation as innovative therapy for chronic pediatric neuropsychiatric disorder – STIPED (STIPED)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Due to lack of targeted interventions, compliance issues, insufficient effect sizes and a high non-responder rate to currently available interventions, there is an urgent need to develop innovative and new interventions for chronic paediatric neuropsychiatric disorders, such as Attention-Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD). Transcranial direct current stimulati ...
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 12

 TERMINÉ 

AnTBiotic – progressing TB drug candidates to clinical proof of concept (anTBiotic)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Tuberculosis (TB) today rivals HIV/AIDS as the leading cause of death from infectious diseases. The number of TB patients has never been higher and the growing proportion of drug-resistant TB is threatening control strategies both in the developing and developed world, Eastern Europe being a particularly worrying point in case. The anTBiotic consortium aims to fuel the long-term TB clinical pipeli ...
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 5

 TERMINÉ 

Evaluating a Combination of Immune-based Therapies to Achieve a Functional Cure of HIV Infection (HIVACAR)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

The main goal of HIVACAR proposal is to change the current paradigm of HIV treatment by obtaining a functional cure for HIV (i.e., control of viral load to levels below the threshold of 50 copies/ml and maintenance of high CD4+ T-cell count after discontinuation of antiretroviral therapy) thanks to effectively targeting residual virus replication and viral reservoirs. In order to do so, the planne ...
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 16

 TERMINÉ 

MONTADO & CLIMATE; A NEED TO ADAPT (LIFE-Montado-adapt)

Date du début: 1 sept. 2016, Date de fin: 1 sept. 2021,

Background Mediterranean ecosystems have been identified as being among the most likely to be impacted by climate change. A further clear trend towards drier and hotter conditions is predicted in the Mediterranean area. Here, substantial warming (about 1.5°C in winter and almost 2°C in summer) and a significant decrease in precipitation (5-10%) is likel ...
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 17

 TERMINÉ 

Demonstration of a new agro-silvo-pastoral land use to improve farm profitability in mountain areas (LIFE+ POLYFARMING)

Date du début: 1 juil. 2016, Date de fin: 30 juin 2021,

Background Mediterranean mountain ecosystems are characterised by low production capacity, mainly due to three factors: climatic conditions, difficulties using machinery and low organic matter content of the soils (low fertility). These factors have led to the abandonment of traditional multifunctional management, which has contributed to soil degradation ...
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 2

 TERMINÉ 

Building Innovative Green Hydrogen systems in an Isolated Territory: a pilot for Europe (BIG HIT)

Date du début: 1 mai 2016, Date de fin: 30 avr. 2021,

BIG HIT will create a replicable hydrogen territory in Orkney (Scotland) by implementing a fully integrated model of hydrogen production, storage, transportation and utilisation for heat, power and mobility. BIG HIT will absorb curtailed energy from two wind turbines and tidal turbines on the islands of Eday and Shapinsay, and use 1.5MW of PEM electrolysis to convert it into ~50 t pa of hydrogen. ...
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 12

 TERMINÉ 

DISCOVERER – DISruptive teChnOlogies for VERy low Earth oRbit platforms (DISCOVERER)

Date du début: 1 janv. 2017, Date de fin: 31 mars 2021,

We envision a radical redesign of Earth observation platforms for sustained operation at significantly lower altitudes than the current state of the art, using a combination of new aerodynamic materials, aerodynamic control and air-breathing electric propulsion for drag-compensation, for a variety of observation methods with the aim of creating a new platform paradigm.This vision requires foundati ...
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 9

 TERMINÉ 

PRevention Of Malnutrition In Senior Subjects in the EU (PROMISS)

Date du début: 1 avr. 2016, Date de fin: 31 mars 2021,

PROMISS (PRevention Of Malnutrition In Senior Subjects in the EU) is a multi-country project aiming to turn the challenge of tackling malnutrition in community-dwelling older persons into an opportunity for healthy ageing for the future. The PROMISS consortium contains worldwide expertise in epidemiology, clinical trials, geriatrics, nutrition, physical activity, microbiomics, as well as in behavi ...
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 24

 TERMINÉ 

Training Network to Understand and Exploit Mechanisms of Sensory Perception in Bacteria (PATHSENSE)

Date du début: 1 avr. 2017, Date de fin: 31 mars 2021,

The PATHSENSE (Pathogen Sensing) ETN will bring together an interdisciplinary team of world-leading researchers from Europe to tackle a highly ambitious scientific project, focusing on the molecular mechanisms of sensory perception in bacterial pathogens. PATHSENSE will establish an innovative doctoral training programme that will deliver 13 PhD graduates and high-impact scientific outputs. The re ...
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 14

 TERMINÉ 

Holistic Surface Water and Groundwater Management for Sustainable Cities (Water4Cities)

Date du début: 1 mars 2017, Date de fin: 28 févr. 2021,

Urban water management becomes progressively more challenging in the view of population growth and increasing complexity of water management infrastructure. In this line, there is an ever increase demand from the water providers’ and public authorities’ perspective to critically evaluate the existing water ecosystems at city level in respect to the water supply, waste water treatment, reuse potent ...
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 7

 TERMINÉ 

Science and Innovation with thunderstorms (SAINT)

Date du début: 1 mars 2017, Date de fin: 28 févr. 2021,

Lightning is an extremely energetic electric discharge process in our atmosphere. It significantly affects the concentration of greenhouse gases and it threatens electrical and electronic devices, in particular, when placed on elevated structures like wind turbines or aircraft, and when these structures are built with modern composite materials with inherently low electric conductivity. In additio ...
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 10

 TERMINÉ 

Revalorisation of vegetable processing industry remnants into high-value functional proteins and other food ingredients (GreenProtein)

Date du début: 1 sept. 2016, Date de fin: 28 févr. 2021,

The EU28 imports 77% of the protein it requires, for food or feed, representing an important vulnerability for our economy, risking our self-sufficiency and food security. Food waste is a top issue, representing losses costing €442/ton of produced food material, plus environmental and ethical problems in EU.GreenProtein aims at a major innovation for these two needs by producing high-added value, ...
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 9

 TERMINÉ 

Africa-EU Innovation Alliance for Water and Climate (AfriAlliance)

Date du début: 1 mars 2016, Date de fin: 28 févr. 2021,

The main objective of AfriAlliance is for African and European stakeholders to work together in the areas of water innovation, research, policy, and capacity development to prepare Africa for future Climate Change challenges. There are many but fragmented initiatives and networks in place, therefore we will not create new but will consolidate existing networks of scientists, decision makers, pract ...
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 16

 TERMINÉ 

PROMOTING ACTIVE AGEING: FUNCTIONAL NANOSTRUCTURES FOR ALZHEIMER’S DISEASE AT ULTRA-EARLY STAGES. (PANA)

Date du début: 1 mars 2016, Date de fin: 28 févr. 2021,

Alzheimer’s disease (AD) is the leading cause of dementia and loss of autonomy in the elderly, implying a progressive cognitive decline and limitation of social activities. Progressive aging of EU population will increase the magnitude of this problem in the next decades. Currently, there is not an effective method for the early diagnosis of AD. Therefore, there is an urgent need to develop new ef ...
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 11

 TERMINÉ 

New siRNA Nanotherapy for Inflammatory Bowel Diseases, targeting Janus kinase 3 (NEW DEAL)

Date du début: 1 févr. 2017, Date de fin: 31 janv. 2021,

Inflammatory bowel diseases (IBD) are the second most common immune-mediated disorders in Europe, affecting more particularly young people. The current therapies, including antibodies, show three main drawbacks: efficacy, tolerability and convenience. NEW DEAL solution will offer radical therapeutic progress for all IBD patients, thanks to the improved efficacy and increased safety of the specific ...
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 11

 TERMINÉ 

REnaissance of Places with Innovative Citizenship and TEchnolgy (REPLICATE)

Date du début: 1 févr. 2016, Date de fin: 31 janv. 2021,

The objective of REPLICATE is to demonstrate Smart City technologies in energy, transport and ICT in districts in San Sebastia, Florence and Bristol addressing urban complexity and generate replication plans in other districts and in follower cities of Essen,Nilufer and Lausanne.Main challenges for cities are to increase the overall energy efficiency, to exploit better local resources in terms of ...
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 37

 TERMINÉ 

PROTECTion against Endocrine Disruptors;Detection, mixtures, health effects, risk assessment and communication. (PROTECTED)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

PROTECTED aims to develop expertise and protective capabilities against Endocrine Disruptors (EDs). EDs and their mixtures are a modern day health concern leading to failing ecological systems, poor agricultural production and health effects such as obesity, cancer and infertility. While analytical methods have advanced enormously, focus has been mainly on synthetic chemicals, overlooking emerging ...
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 11

 TERMINÉ 

Biomacromolecules from municipal solid bio-waste fractions and fish waste for high added value applications. (DAFIA)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Municipal solids waste (MSW) are collected by municipalities and represents more than 500 kg/capita (EU-27 average), 300 million tonnes overall every year in the EU-32. Currently, approximately 50% of this volume is landfilled. More than 1.3 million tonnes of Marine rest raw material (MRRM) are generated in Europe each year. Some countries, such as Norway and Denmark, have traditionally for anima ...
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 17

 TERMINÉ 

Smart multifunctional GLA-nanoformulation for Fabry disease (Smart-4-Fabry)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Lysosomal storage disorders (LSD) diseases are a group of rare diseases that currently lack a definitive cure. LSD incidence is about 1:5,000 - 1:10,000, representing a serious global health problem. In the case of Fabry LSD Disease (FD), the deficiency in α-Galactosidase A (GLA) enzyme activity results in the cellular accumulation of neutral glycosphingolipids, leading to widespread vasculopathy ...
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 10

 TERMINÉ 

SustainAble Farming for Effective Aquaculture (SAFE-Aqua)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Aquaculture is an important food source for the world’s growing population. The increasing demand and productivity of aquaculture leads to global trade in breeding stock, genetic material and aquaculture products for human consumption, but also exacerbates the globalization of pathogens.SAFE-Aqua, an international inter- and multidisciplinary consortium, aims to provide scientific solutions to sol ...
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 3

 TERMINÉ 

Virus free Fruit Nurseries (VirFree)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Fruit trees and grapevine are propagated vegetatively and are often grafted. As a result they suffer from a high number of pathogens such as viruses and viroids, a number of which are causing severe yield losses and reduce the productive life of the affected plants. As these pathogens cannot be controlled by the application of chemicals, the most efficient way to combat them is the production and ...
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 15

 TERMINÉ 

Blood test for clinical therapy guidance of non-small cell lung cancer patients (LungCARD)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Lung cancer is the most common cancer worldwide. NSCLC alone make up about 75% of all lung cancers and most hospitals currently test all NSCLC patients for EGFR mutations (pharmacogenomics) for treatment decision (personalised medicine) – i.e., patients with mutation(s) in EGFR gene should receive a EGFR-Tyrosine Kinase Inhibitor (TKI) drug (e.g. afitinib) treatment; while those that do not presen ...
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 8

 TERMINÉ 

Compositional security certification for medium- to high-assurance COTS-based systems in environments with emerging threats (certMILS)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

certMILS develops a security certification methodology for Cyber-physical systems (CPS). CPS are characterised by safety-critical nature, complexity, connectivity, and open technology. A common downside to CPS complexity and openness is a large attack surface and a high degree of dynamism that may lead to complex failures and irreparable physical damage. The legitimate fear of security or function ...
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 9

 TERMINÉ 

REgenerative therapy of intervertebral disc: a double blind phase 2b trial of intradiscal injection of mesenchymal stromal cells in degenerative disc disease of the lomber SPINE unresponsive to conventional therapy (RESPINE)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The World Health Organisation (WHO) has included low back pain in its list of twelve priority diseases. Notably, Degenerative disc disease (DDD) presents a large, unmet medical need which results in a disabling loss of mechanical function. Today, no efficient therapy is available. Chronic cases often receive surgery, which may lead to biomechanical problems and accelerated degeneration of adjacent ...
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 18

 TERMINÉ 

Overcoming the Limits of Diffraction with Superresolution Lighting on a Chip (ChipScope)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The physical laws of diffraction generally limit the spatial resolution of optical systems, being about 200 nm for light in the visible range. Within ChipScope we want to overcome this limit by developing the scientific and technological basis for a completely new approach to optical superresolution, based on semiconductor nano Light Emitting Diode (nanoLED) arrays with individual pixel operation. ...
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 7

 TERMINÉ 

Advanced Materials technologies to QUADRUPLE the Concentrated Solar Thermal current POWER GENERATION (IN-POWER)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The benefits of high efficiency concentrated solar power (CSP) and photovoltaic (PV) are well known: environmental protection, economic growth, job creation, energy security. Those technologies can only be applied properly in regions with annual mean radiation values higher than 1750 kWh/m2 per year. CSP has advantages in front of PV: possible 24h continuous electricity production, electricity and ...
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 11

 TERMINÉ 

Advanced materials solutions for next generation high efficiency concentrated solar power (CSP) tower systems (NEXTOWER)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

NEXTOWER shall introduce a set of innovative materials to boost the performance of atmospheric air-based concentrated solar power (CSP) systems to make them commercially viable. In particular, tower systems are appealing for the great environmental compatibility and offer tremendous potential for efficient (electrical and thermal) power generation. Yet, their industrial exploitation has been so fa ...
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 18

 TERMINÉ 

Demonstration actions to mitigate the carbon footprint of beef production in France, Ireland, Italy and Spain (LIFE BEEF CARBON)

Date du début: 4 janv. 2016, Date de fin: 31 déc. 2020,

Background Beef production generates greenhouse gas (GHG) emissions accounting for six per cent of all human-induced emissions. Nevertheless, studies reveal that knowledge gaps exist among beef farmers about the use of innovative practices to reduce GHG emissions. Beef production can also regulate climate through carbon storage in grassland. This dual rol ...
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 27

 TERMINÉ 

Management of Urban SPAs in Extremadura for the conservation of Lesser kestrel (Falco naumanni) (LIFE- ZEPAURBAN)

Date du début: 1 sept. 2016, Date de fin: 31 déc. 2020,

Background In the Extramadura region, more than 70% of the small falcon lesser kestrel (Falco naumanni) breeding colonies are located in urban centres. In particular, this unique network of 19 urban Special Protection Areas (SPAs) within the EU Natura 2000 network is currently home to over 50% of the region’s lesser kestrel population. A recent survey ...
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 8

 TERMINÉ 

Demonstration of an innovative solution to reduce GHG emissions in vineyards while improves the soil in arid areas (LIFE SARMIENTO)

Date du début: 1 sept. 2016, Date de fin: 31 déc. 2020,

Background Like most economic sectors, agriculture produces greenhouse gases, accounting for around 10% of total CO2 emissions in the EU (4.7 billion tonnes in 2012). In Europe, around 57 million hectares are cultivated for agriculture, of which 5.6% (3 million ha) is devoted to vineyards. The main wastes and by-products from viticulture and winemaking ac ...
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 3

 TERMINÉ 

Synthetic bacterial lipid rafts to optimize industrial bioprocesses (Rafts4Biotech)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Genetic tractability of bacterial cells allows generating synthetic microbial chassis platforms (SMCPs) with remarkable biotechnological applications but their functionality currently faces important off-genome limitations due to deficient protein-protein interactions, unfavorable protein stoichiometry or generation of toxic intermediates that ultimately compromise the industrial production proces ...
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 13

 TERMINÉ 

Single Point Of aTtachment communications empowered by cLoud computing and bIG data analytics running on-top of massively distributed and loosely-coupled Heterogeneous mobile data neTworks (SPOTLIGHT)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

To handle the unprecedented demand for mobile data traffic, different vendors, operators and research programmes have aimed to develop radio access technologies (RATs) that boost physical-layer link capacity, utilize millimeter wave radio, or further densify network topology. Notable steps have also been made towards shifting baseband processing from the (currently) ultra dense network edge to a c ...
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 10

 TERMINÉ 

Predictive Neural Information for Proactive Actions: From Monkey Brain to Smart House Control (Plan4Act)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Planning and mental simulation of actions and outcomes are a major cognitive trait of humans. We predict action consequences and perform goal-directed actions in proactive, forward-looking ways. By contrast, systems that lack predictive planning are reactive and dominated by reflex-like, cumbersome behaviors. Most currently existing brain-machine-interfaces (BMI) fall into this category. Plan4Act ...
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 6

 TERMINÉ 

Composable Models and Software for Robotics Systems (RobMoSys)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

RobMoSys will coordinate the whole community’s best and consorted effort to build an open and sustainable, agile and multi-domain European robotics software ecosystem.RobMoSys envisions an integration approach built on-top-of, or rather around, the current code-centric robotic platforms, by means of the systematic application of model-driven methods and tools that explicitly focus on (system-of-) ...
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 9

 TERMINÉ 

Drug Discovery and Delivery NEtwork for ONcology and Eye Therapeutics (3D NEONET)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Severe ocular disorders are affecting the lives of more than 100Mill people world-wide and at least 25% of the population above 70 years of age, a growing demographic group in EU. More than 8 million people lose their lives to cancer every year, making cancer a leading cause of pre-mature mortality in the world. The main hallmarks of severe eye conditions (i.e angiogenesis, inflammation and vascul ...
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 18

 TERMINÉ 

European Academy for Biomedical Science (ENABLE)

Date du début: 1 juil. 2016, Date de fin: 31 déc. 2020,

The proposed European Academy for Biomedical Science (ENABLE) consortium will connect aspiring European researchers of tomorrow with prominent scientists of today, in particular to inspire and to give them the necessary tools to follow in their footsteps. ENABLE will organize peer-reviewed symposia celebrating European life science achievements from molecule to man/patient. These symposia will hav ...
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 6

 TERMINÉ 

Arrhythmias monitoring and comprehensive care (RITMOCORE)

Date du début: 1 nov. 2016, Date de fin: 31 déc. 2020,

RITMOCORE is addressing the evolution in the treatment of elderly patients with arrhythmias using or in need of a pacemaker. The proposed approach promotes a comprehensive model of care including: empowerment of general practitioners and integration of care pathways through the adequate information sharing; remote monitoring of pacemakers; home monitoring of vital signs using wearables, Apps and a ...
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 9

 TERMINÉ 

Smart high-frequency environmental sensor networks for quantifying nonlinear hydrological process dynamics across spatial scales (HiFreq)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2020,

Regulators and industries are challenged by the difficulty to analyse and predict the impact of nonlinear environmental processes on short-term and long-term responses of ecosystems to environmental change. Until very recently, the development of most conventional monitoring, forecasting and prediction tools has been based on the assumption of stationary environmental systems. In the context of gl ...
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 18

 TERMINÉ 

Sustainable Algae Biorefinery for Agriculture aNd Aquaculture (SABANA)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2020,

SABANA aims at developing a large-scale integrated microalgae-based biorefinery for the production of biostimulants, biopesticides and feed additives, in addition to biofertilizers and aquafeed, using only marine water and nutrients from wastewaters (sewage, centrate and pig manure). The objective is to achieve a zero-waste process at a demonstration scales up to 5 ha sustainable both environmenta ...
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 11