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13 projets européens trouvés

Recherche sur 125080 projets européens

 TERMINÉ 

Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging with ‘Minimally-Invasive Segmental Artery Coil-Embolization’: A Randomized Controlled Multicentre Trial (PAPA-ARTIS)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Chronic aortic aneurysms are permanent and localized dilations of the aorta that remain asymptomatic for long periods of time but continue to increase in diameter before they eventually rupture. Left untreated, the patients’ prognosis is dismal, since the internal bleeding of the rupture brings about sudden death. Although successful treatment cures the disease, the risky procedures can result in ...
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 26

 TERMINÉ 

BIOlogical therapy CYCLEs towards tailored, needs-driven, safer and cost-effective management of Crohn’s disease (BIOCYCLE)

Date du début: 1 avr. 2015, Date de fin: 31 mars 2021,

"The BIOCYCLE Project proposes to test and critically assess the benefits and risks of an innovative regimen for improving the treatment of Crohn’s disease (CD), a chronic immune-mediated inflammatory disease affecting the gastro-intestinal tract of an increasing number of patients. Currently, the combination of anti-TNFα monoclonal antibodies and immunosuppressants used without interruption is th ...
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 13

 TERMINÉ 

Clinical study in Parkinson's disease with two unique goals: 1) Proof-of-concept of CDNF protein for disease modification; 2) Validation of clinically tested device for intracerebral drug delivery (TreatER)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,

The main focus of TreatER is conducting a randomized, placebo-controlled, first-in-human, proof-of-concept, safety and efficacy study of intracerebrally administered CDNF protein therapy in patients with Parkinson’s disease (PD), using a neurosurgically implanted Drug Delivery System (DDS), which will also be clinically validated in the study. Thus the TreatER project has two independent goals, ei ...
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 12

 TERMINÉ 

EURO EWING Consortium – International Clinical Trials to Improve Survival from Ewing Sarcoma (EEC)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,

Ewing Sarcomas (ES) are fatal, rare bone cancers particularly affecting young people. About 60% of patients achieve long term survival with current treatment but there has been no improvement in this proportion for 25 years. Treatment is unsuccessful because chemotherapy fails to prevent the development of, or to effectively treat established, metastases. In addition, of the 600 new cases of ES o ...
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 21

 TERMINÉ 

Development of a prophylactic treatment for the prevention of fetal/neonatal alloimmune thrombocytopenia (FNAIT) (PROFNAIT)

Date du début: 1 août 2012, Date de fin: 31 juil. 2018,

Objective--The project aims to develop an anti HPA-1a immunoglobulin (IgG), Tromplate® that can prevent post delivery immunisation of the mother against the Human Platelet Antigen-1a (HPA-1a). This prophylactic treatment will prevent Fetal/Neonatal Alloimmune Thrombocytopenia (FNAIT) in the fetus/newborn in subsequent pregnancies.FNAIT--FNAIT is a rare but potentially serious condition which affec ...
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 13

 TERMINÉ 

Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in EUrope (EU-CERT-ICD)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

An estimated 500.000 sudden cardiac deaths (SCD) occur each year in the European Union. Patients at risk for SCD may benefit from prophylactic treatment with an implantable cardioverter-defibrillator (ICD). ICD implantations have dramatically increased in recent years leading to multi-billion Euros of costs with significant regional disparities across Europe. Information on risks, benefits and cos ...
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 27

 TERMINÉ 

European multicentre, randomised, phase III clinical trial of hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke (EuroHYP-1)

Date du début: 1 févr. 2012, Date de fin: 31 janv. 2017,

The consortium led by UKER and EuroHYP, the European Stroke Research Network for Hypothermia, proposes a large, multicentre clinical trial which will assess mild hypothermia as a novel treatment for ischemic stroke.Stroke is the second cause of death world-wide and the second cause of lost disability-adjusted life years in high-income countries. Stroke incidence rises exponentially with age, so it ...
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 38

 TERMINÉ 

Regional Digital Agendas for Healthcare (READI FOR HEALTH)

Date du début: 1 sept. 2013, Date de fin: 31 août 2016,

READi for Health aims to strengthen the research potential of four leading eHealth regions (Murcia, Skane, Oulu and Midi-Pyrénées) by supporting their triple helix clusters to become world-class players in domains related to the EU Digital Agenda for Healthcare.The major limitation of the eHealth market today is not scarcity of technology, but that innovationup-take is slow compared with other sec ...
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 9

 TERMINÉ 

NEURAL TRANSPLANTATION IN THE TREATMENT OF PATIENTS WITH PARKINSON’S DISEASE (TRANSEURO)

Date du début: 1 janv. 2010, Date de fin: 30 juin 2016,

There are currently no cures for Parkinson's disease (PD) but one of the most effective reparative therapies in patients to date has been with allotransplants of dopamine (DA) neuroblasts obtained from fetal ventral mesencephalic (VM) tissue. However, this cell transplantation approach has given inconsistent results, with some patients doing extremely well and coming off anti-PD medication for yea ...
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 15

 TERMINÉ 

Phase II clinical trial of PDGF-BB for the neurological regeneration and recovery in Parkinson´s disease (NRT)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

"The goal of this project is to perform a European phase II clinical trial to demonstrate that PDGF-BB acts as a unique regenerative therapy for Parkinson’s Disease (PD), aimed at reversing the course of the disease, by promotion of endogenous brain repair mechanisms. Current pharmacological therapies for PD carry side-effects and become less effective as the disease progresses. This causes immen ...
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 10

 TERMINÉ 

"ECNIS2: towards ECNIS Centre for Research and Education on Cancer, Environment and Food" (ECNIS2)

Date du début: 1 juin 2011, Date de fin: 31 mai 2013,

"The proposed project ECNIS2 aims at continuing the integrative and coordinative works initiated during ECNIS network with an ultimate goal of transforming network into a virtual centre, the European Centre for Research and Education on Cancer, Environment and Food (ECRECEF).ECNIS has already laid foundations for the development of the centre by bringing together researchers from different discipl ...
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 23

 TERMINÉ 

Europe against Cancer: Optimisation of the Use of Registries for Scientific Excellence in research (EUROCOURSE)

Date du début: 1 avr. 2009, Date de fin: 30 sept. 2012,

"EUROCOURSE will tackle fragmentation in the funding and usage of cancer registries in Europe. It will do so by exploring ways to link and integrate national/regional programmes aimed at supporting cancer registries and research carried out using registry data. At the same time EUROCOURSE is seeking to optimize the use of cancer registration data for the amelioration of cancer control and the stre ...
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 15

 TERMINÉ 

The Development of a Next Generation Probiotic Supplement for Treatment and Prevention of Antibiotic Associated Diarrhoea (Qualvivo)

Date du début: 1 juil. 2009, Date de fin: 30 juin 2011,

Stress, medications, global travel and an imbalanced diet are having an increasingly adverse effect on the health of the European population derived from weakened immune systems. This manifests itself in the occurrence of serious ailments such as acute infectious diarrhoea (AID), ulcerative colitis (UC), travellers’ diarrhoea (TD) and antibiotic associated diarrhoea (AAD). Specifically, in the cas ...
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 6