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 TERMINÉ 

Advanced Immunization Technologies (ADITEC)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2017,

Vaccines so far have been developed mostly by following an empiric approach. To prevent and possibly cure unresolved and emerging infectious diseases we need to fully exploit the potential of the human immune system. Progress in science and technology makes it possible to achieve what was previously deemed impossible. The scope of this project is to produce knowledge necessary to develop novel and ...
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 53

 TERMINÉ 
Despite the increasing number of macromolecules with potential impact in the treatment of devastating systemic diseases, these therapies have failed to deliver on their expectations because they cannot be administered in the fashion which is most cost efficient and has the highest patient compliance: the oral route. The availability of an oral form of administration could lead to a great improveme ...
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 20

 TERMINÉ 
Sigmoid Pharma has developed an innovative product, CyCol®, to treat patients with moderate-severe ulcerative colitis, a disease that affects 1 million patients in Europe. CyCol® is enabled using Sigmoid’s proprietary SmPill® nanoemulsion-based technology to target a known and powerful drug, cyclosporine, directly to inflamed colons. In Phase II human studies, CyCol® was proven to be effective and ...
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 1

 TERMINÉ 

Development of an oral Helicobacter Pylori vaccine (HELICOVAXOR)

Date du début: 1 oct. 2012, Date de fin: 31 déc. 2014,

"Helicobacter pylori infection is highly prevalent worldwide and is an important cause of gastritis, peptic ulcer disease, and significantly gastric cancer. Because eradication requires treatment with multidrug regimens, there exists a very strong need for a vaccine to prevent initial infection.Immunization with H pylori protein subunits in humans has shown adjuvant-related adverse effects and onl ...
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 11

 TERMINÉ 
Particles and granules play a key role in process efficacy and final product quality for numerous industries including pharmaceuticals, food, nutritionals and cosmetics. Particle physics governs process variables such as flow, blending, granulation, compression and coating. These variables can have a significant effect on final product behaviour such as blend homogeneity, drug absorption rates, pr ...
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 11