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Memory loss in Alzheimer disease: underlying mechanisms and therapeutic targets (MEMOSAD)
Date du début: 1 janv. 2008, Date de fin: 30 juin 2011,
"MEMOSAD aims at defining the molecular mechanisms of Abeta- and Tau-induced synaptotoxicity and at developing disease-modifying therapeutics for the prevention of memory loss in Alzheimer disease (AD). Insoluble aggregates of the two proteins provide the pathological hallmarks of this incurable brain disorder. Early stage AD is characterized by a remarkably pure impairment of declarative memory a ...
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