2 projets européens trouvés
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TERMINÉ
3-O-sulfated heparan sulfate translocation in altered membrane biology: A newstrategy for early population screening and halting Alzheimer’s neurodegeneration (ArrestAD)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
ArrestAD proposes a novel and visionary thinking resulting from the demonstration of the central role of a particular heparan sulfate species at the intracellular level in neurons and in circulating cells in the molecular pathology of Alzheimer’s disease (AD). AD is a societal challenge for which there is neither prevention nor possible cure. Research in the field has long been refining classic co ...
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TERMINÉ
Imaging the Force of Cancer (FORCE)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
Cancer is the second leading cause of mortality in EU member states with ~90% of all cancer deaths caused by metastatic spread. Despite its significance, measuring metastatic potential as well as potential indicators of therapy efficacy remain unmet clinical challenges. Recently, it has been demonstrated in vitro, that aggressive metastatic cells pull on their surroundings suggesting that metastat ...
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