4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
iABC Programme (IABC PROGRAMME)
Date du début: 1 août 2015, Date de fin: 31 juil. 2020,
Cystic Fibrosis (CF) is a common fatal inherited disease with a frequency of 1 in 2500 live births, affecting approximately 36,000 (0.737/10,000) people in the EU. Chronic bacterial pulmonary infection leading to an irreversible decline in lung structure and function is the main cause of mortality and morbidity in patients with CF, with more than 95% of deaths due to respiratory failure. Pseudomon ...
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21
Participants partenaires
TERMINÉ
Cannabinoid receptors CB1 in schizophrenia: role of brain mitochondrial activity and astroglial signalling (SCHIZO-mtCB1)
Date du début: 1 févr. 2015, Date de fin: 31 janv. 2017,
"Schizophrenia is a severe psychiatric disorder characterized by a series of ""positive"" and ""negative"" symptoms, which eventually lead to strong sufferance, social isolation and occupational impairment. Via activation of type-1 cannabinoid receptors (CB1), cannabinoids are known to induce schizophrenic-like symptoms, which are major caveats in the possible therapeutic use of these compounds. O ...
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1
Participant partenaire
TERMINÉ
Characterization of the role of Scrib1 and Vangl2 in neuronal migration (MigPCP)
Date du début: 1 mars 2012, Date de fin: 28 févr. 2015,
Although the cerebral cortex is responsible for all the intellectual life that makes us human, we know remarkably little about how this amazing structure is formed. We do know, however, that genetic conditions in which the cortex is not formed properly have devastating consequences. Neurological disorders are frequently associated with developmental brain malformations. Progress toward understandi ...
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1
Participant partenaire
TERMINÉ
Role of Rnd proteins in the regulation of dendrite, spine and synapse formation in the developing hippocampus and their implication in hippocampal-dependent memory (RhoHippoMemo)
Date du début: 2 juil. 2012, Date de fin: 1 juil. 2014,
The rapidly growing elderly population and the increasing occurrence of memory disorders make the promotion of “healthy ageing” and the treatment of these disorders a major challenge in our modern societies. However, the development of treatments is hindered mainly because the biological basis of memory is still unclear. For this reason a better understanding of the mechanisms regulating memory pr ...
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