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 TERMINÉ 

Early-life stressors and LifeCycle health (LIFECYCLE)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Early life is an important window of opportunity to improve health across the full lifecycle. European pregnancy and child cohort studies together offer an unique opportunity to identify a wide range of early life stressors linked with individual biological, developmental and health trajectory variations, and to the onset and evolution of non-communicable diseases. LIFECYCLE will establish the Eur ...
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 19

 TERMINÉ 

LIFE URBAN-ADAPT: demonstrating urban climate adaptation and resilience in inner city Rotterdam (LIFE URBAN-ADAPT)

Date du début: 16 juil. 2015, Date de fin: 31 déc. 2021,

...ause of increased precipitation and rising water levels; 2. Increased temperatures resulting from the urban heat island effect; and 3. Deterioration of native flora and fauna on land and in water. Rotterdam is the first major European city with an approved climate adaptation strategy. Implementation in public areas is ongoing, but to make real strides, climate adaptation has to be significantly ...
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 3

 TERMINÉ 

Combatting Bacterial Resistance in Europe - Molecules against Gram Negative Infections (COMBACTE-MAGNET)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2021,

Antimicrobial resistance (AMR) is a major global public health threat, and most troublesome is the rapid emergence and dissemination of multidrug resistant (MDR) Enterobacteriaceae, Acinetobacter species and Pseudomonas aeruginosa. There is an unmet medical need to prevent P. aeruginosa infection in critically ill patients and to develop new antibiotics for infections caused by Gram-negative bacte ...
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 44

 TERMINÉ 

Rotterdam, Umea and Glasgow: Generating Exemplar Districts In Sustainable Energy Deployment (Ruggedised)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2021,

The RUGGEDISED project will create urban spaces powered by secure, affordable and clean energy, smart electro-mobility, smart tools and services. The overall aims are:1. Improving the quality of life of the citizens, by offering the citizens a clean, safe, attractive, inclusive and affordable living environment.2. Reducing the environmental impacts of activities, by achieving a significant reducti ...
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 34

 TERMINÉ 

Global Markets, Local Creativities

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

... Glasgow, Scotland and Barcelona, Spain. In the third semester students choose between a track on the history of globalization and the role of creative industries delivered at the Erasmus University, Rotterdam in the Netherlands, and a track specializing in marketing, entrepreneurship and development at Goettingen University, Germany. The final semester will be spent researching and writing a diss ...
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 4

 TERMINÉ 

Worlds of Imagination. A Comparative Study of Film Tourism in India, Nigeria, Jamaica, South Korea and the United Kingdom.Worlds of Imagination: A Comparative Study of Film Tourism in India, Niger (Film Tourism)

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

This research project focuses on film tourism: the phenomenon of people visiting locations from popular films or TV series. Recent years have seen a dramatic, worldwide increase of this type of tourism, with far-reaching implications for the experience and organization of landscapes. While the number of empirical studies on film tourism is growing, most have been limited to isolated, Western examp ...
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 1

 TERMINÉ 

Origins of Alzheimer's disease across the life-course (ORACLE)

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

...ation-based samples totalling 40,829 persons that together cover the entire life-span: children in Generation R Study (in utero – 18 yrs); parents in Generation R Study (18–45 yrs); and the Rotterdam Study (45 yrs – death). Reserve will be quantified structurally using imaging techniques that measure volumetry, perfusion and connectivity as well as functionally by measuring cognitive and non-cogni ...
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 1

 TERMINÉ 

Cerebellar modules and the Ontogeny of Sensorimotor Integration (COSI)

Date du début: 1 juin 2016, Date de fin: 31 mai 2021,

The perfect execution of a voluntary movement requires the appropriate integration of current bodily state, sensory input and desired outcome. To assure that this motor output becomes and remains appropriate, the brain needs to learn from the result of previous outputs. The cerebellum plays a central role in sensorimotor integration, yet -despite decades of studies- there is no generally excepted ...
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 1

 TERMINÉ 

TRANSATLANTIC TRADE AND INVESTMENT PARTNERSHIP-INTERNATIONAL TRAINING NETWORK (TTIP-ITN)

Date du début: 1 avr. 2017, Date de fin: 31 mars 2021,

The EU currently is negotiating a controversial Transatlantic Trade and Investment Partnership (TTIP) agreement with the USA, the main features of which will be the abolition of tariffs, the reduction of non-tariff barriers to trade between the EU and the USA and the introduction of a dispute settlement mechanism. The objective of the proposed TTIP Innovative Training Network (TTIP-ITN) is to fost ...
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 11

 TERMINÉ 

SPIDIA for Personalized Medicine - Standardisation of generic Pre-analytical procedures for In-vitro DIAgnostics for Personalized Medicine (SPIDIA4P)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Molecular in vitro diagnostics and biomedical research have allowed great progress in personalised medicine but further progress is limited by insufficient guidelines for pre-analytical workflow steps (sample collection, preservation, storage, transport, processing etc.) as well as by insufficient quality assurance of diagnostic practice. This allows using compromised patients’ samples with post c ...
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 21

 TERMINÉ 

Implementation of cost-optimized childhood vision and hearing screening programmes in middle-income countries in Europe (EUSCREEN)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Screening for vision and hearing disorders in children has shown to be highly effective. EU-directive 16620/11 invites EU-member states to give priority to such screening programmes. Early detection and treatment of a lazy eye (prevalence 3%) prevents lifelong visual impairment. Early detection and treatment of hearing impairment (prevalence 0.15%) prevents delayed speech and language development. ...
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 10

 TERMINÉ 

Regulated Assembly of Molecular Machines for DNA REPAIR: a Molecular Analysis training Network (DNAREPAIRMAN)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The European Training Network DNAREPAIRMAN aims to train a new generation of innovative young scientists in cutting edge biophysical research methodology to address central questions in biology concerning the mode of action of critical molecular machines with relevance for human health. The Network consists of a highly collaborative consortium consisting of 12 participants coming from academia, in ...
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 8

 TERMINÉ 

Translational Research Network in Prostate Cancer (TransPot)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The Translational Research Network for Prostate Cancer (TransPot) program adopts an innovative, multidisciplinary approach, providing highly sought-after, effective solutions for incurable prostate cancer (PC).The TransPot scientific objective is to obtain an unmatched depth of molecular, mechanistic and informatics systems-level disease understanding in order to improve the prognosis and treatmen ...
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 11

 TERMINÉ 

Personalised Risk assessment in febrile illness to Optimise Real-life Management across the European Union (PERFORM)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

The management of febrile patients is one of the most common and important problems facing healthcare providers. Distinction between bacterial infections and trivial viral infection on clinical grounds is unreliable, and as a result innumerable patients worldwide undergo hospitalization, invasive investigation and are treated with antibiotics for presumed bacterial infection when, in fact, they ar ...
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 19

 TERMINÉ 

Controlling Cartilage to Bone Transitions for Improved Treatment of Bone Defects and Osteoarthritis (CarBon)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

A well-functioning locomotor system is essential for human well-being. This is an important consideration in our aging population with the increased associated costs of ensuring high quality of life. Many people suffer from diseases of the locomotor system, such as bone defects or osteoarthritis, for which current treatments are insufficient. To develop new treatments, CarBon includes 6 academic p ...
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 9

 TERMINÉ 

Improving Quality of Care in Europe (IQCE)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Improving quality of care has been given too little attention in health economic research in the past although it is the central goal of health care systems in Europe. The proposed ETN on “Improving Quality of Care in Europe (IQCE)” aims to address this gap and has the following aims: 1) Create new evidence and improve existing health economic research in the field of quality of care. Research gap ...
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 8

 TERMINÉ 

Ears, Eyes and Mind: The ‘SENSE-Cog Project’ to improve mental well-being for elderly Europeans with sensory impairment (SENSE-Cog)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Mental, cognitive, vision and hearing health problems in elderly people are amongst the top 10 public health challenges in Europe. They frequently occur co-concurrently and have an additive negative effect on quality of life and mental well-being. To address this negative impact, and promote mental well-being, particularly from a gender and minority community perspective, SENSE-Cog's aim is to: (1 ...
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 18

 TERMINÉ 

Bayesian markets for unverifiable truths (BayesianMarkets)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Subjective data play an increasing role in modern economics. For instance, new welfare measurements are based on people’s subjective assessments of their happiness or their life satisfaction. A problem of such measurements is that people have no incentives to tell the truth. To solve this problem and make those measurements incentive compatible, I will introduce a new market institution, called Ba ...
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 1

 TERMINÉ 

European HIV Vaccine Alliance (EHVA): a EU platform for the discovery and evaluation of novel prophylactic and therapeutic vaccine candidates (EHVA)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Many HIV vaccine concepts and several efficacy trials have been conducted in the prophylactic and therapeutic fields with limited success. There is an urgent need to develop better vaccines and tools predictive of immunogenicity and of correlates of protection at early stage of vaccine development to mitigate the risks of failure. To address these complex and challenging scientific issues, the Eur ...
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 43

 TERMINÉ 

Liaison in Scientific Training for European auditory Neuroscience (LISTEN)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2020,

This ITN will train 10 ESRs to meet the urgent need for translation of Auditory Neuroscience into commercial and pharmaceutical products to treat hearing disorders including tinnitus. Tinnitus is the debilitating perception of imaginary sound that is often associated with hearing loss. This Liaison in Scientific Training for European auditory Neuroscience (LISTEN) is a consortium of top hearing sc ...
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 9

 TERMINÉ 

Common mechanisms and pathways in Stroke and Alzheimer's disease. (CoSTREAM)

Date du début: 1 déc. 2015, Date de fin: 30 nov. 2020,

Common mechanisms and pathways in Stroke and Alzheimer's disease.It has long been recognized that stroke and (Alzheimer’s Disease) AD often co-occur and have an overlapping pathogenesis. As such, these two diseases are not considered fellow travelers, but rather partners in crime. This multidisciplinary consortium includes epidemiologists, geneticists, radiologists, neurologists with a longstandin ...
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 11

 TERMINÉ 

Embryonic origins of cardiovascular health in later life: disentangling early causal pathways in a lifecourse perspective (EMBRYOandLATERHEALTH)

Date du début: 1 sept. 2015, Date de fin: 31 août 2020,

Children born preterm or with a small size at birth have increased risks of cardiovascular disease and type 2 diabetes in adulthood. These intriguing associations strongly suggest that common diseases have at least part of their origins in early fetal life. From both an etiological and preventive perspective, it is important to disentangle the early fetal critical periods and causal pathways. An a ...
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 1

 TERMINÉ 

EU-TOPIA: TOWARDS IMPROVED SCREENING FOR BREAST, CERVICAL AND COLORECTAL CANCER IN ALL OF EUROPE (EU-TOPIA)

Date du début: 1 sept. 2015, Date de fin: 31 août 2020,

Breast, colorectal and cervical cancer cause 250,000 deaths each year, representing 20% of EU-cancer mortality. Although important progress has been made in both detection and treatment, there is persisting inequity in progress to reduce its burden. Screening programmes vary substantially between countries and in most long-term effectiveness of screening has not yet been assessed. The objective of ...
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 7

 TERMINÉ 

Towards solving myopia: from genes to pathways using an integrated approach (MYOP-PATH)

Date du début: 1 sept. 2015, Date de fin: 31 août 2020,

Background: Myopia (near-sightedness) is a growing public health issue due to its rapidly rising prevalence. In particular high myopia carries a significant risk of blindness for which there are no treatment options. The disease etiology of this trait is complex and largely unknown. We recently identified a large number of disease loci and genes, which provide significant clues for pathogenic path ...
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 1

 TERMINÉ 

iABC Programme (IABC PROGRAMME)

Date du début: 1 août 2015, Date de fin: 31 juil. 2020,

Cystic Fibrosis (CF) is a common fatal inherited disease with a frequency of 1 in 2500 live births, affecting approximately 36,000 (0.737/10,000) people in the EU. Chronic bacterial pulmonary infection leading to an irreversible decline in lung structure and function is the main cause of mortality and morbidity in patients with CF, with more than 95% of deaths due to respiratory failure. Pseudomon ...
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 21

 TERMINÉ 

PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke (PRECIOUS)

Date du début: 1 juin 2015, Date de fin: 31 mai 2020,

Every year, 1.3 million Europeans have a stroke and one million ultimately die of stroke. One third of stroke patients remain dependent on the help of others. The annual costs for stroke care in Europe are estimated at € 64.1 billion. Stroke incidence increases almost exponentially with age, and the personal, societal, and economic burden of stroke is therefore largely driven by its frequent occur ...
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 20

 TERMINÉ 

Aiding Social Protection: the political economy of externally financing social policy in developing countries (aidsocpro)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,

This research proposal explores the political economy of international development assistance (aid) directed towards social expenditures, examined through the lens of a particular financial quandary that has been ignored in the literature despite having important economic and political repercussions. The quandary is that aid cannot be directly spent on expenditures denominated in domestic currency ...
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 1

 TERMINÉ 

Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI)

Date du début: 1 oct. 2013, Date de fin: 31 mars 2020,

Traumatic Brain Injury (TBI) is a major cause of death and disability, leading to great personal suffering to victim and relatives, as well as huge direct and indirect costs to society. Strong ethical, medical, social and health economic reasons therefore exist for improving treatment. The CENTER-TBI project will collect a prospective, contemporary, highly granular, observational dataset of 5400 p ...
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 44

 TERMINÉ 

Standardization and Development of Assays for Assessment of Influenza Vaccines Correlates of Protection (FLUCOP)

Date du début: 1 mars 2015, Date de fin: 29 févr. 2020,

Background: Influenza viruses cause annual epidemic and occasional pandemics, both of which induce significant morbidity and mortality. Influenza infections affect all age groups but children and adults over the age of 65 are at most risk of developing severe disease.Vaccination is the most effective approach to reduce the impact of annual influenza outbreaks and potential pandemics, however, the ...
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 26

 TERMINÉ 

Zoonotic Anticipation and Preparedness Initiative (ZAPI)

Date du début: 1 mars 2015, Date de fin: 29 févr. 2020,

Emerging infectious diseases are occurring at increasing frequency in Europe and other regions of the world, having profound impacts on public and/or veterinary health as well as disruptive effects on sector, regional or even global economy. The predominantly zoonotic nature of emerging pathogens calls for a One Health approach uniting the human medical and veterinary fields, dedicated to swiftly ...
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 21

 TERMINÉ 

Optogenetic Protein Therapy for Multiple Sclerosis (OPTOGENERAPY)

Date du début: 1 janv. 2017, Date de fin: 31 janv. 2020,

Optogenerapy proposes a new interferon-ß (IFN-ß) drug delivery system to revolutionize Multiple Sclerosis treatment.The aim is to develop and validate a new bio-electronic cell based implant device to be implanted subcutaneously providing controlled drug release during at least 6 months. The cell confinement within a chamber sealed by a porous membrane allows the device to be easily implanted or r ...
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 11

 TERMINÉ 

Data-driven models for Progression Of Neurological Disease (EuroPOND)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

EuroPOND will develop a data-driven statistical and computational modeling framework for neurological disease progression. This will enable major advances in differential and personalized diagnosis, prognosis, monitoring, and treatment and care decisions, positioning Europe as world leaders in one of the biggest societal challenges of 21st century healthcare. The inherent complexity of neurologica ...
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 9

 TERMINÉ 

Training network for Research on molecUlar and Biomechanical Interactions in CONnective tissue disorders (RUBICON)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

RUBICON will establish a global network for staff exchange of scientists and for research training focussed on connective tissue disorders. It will bring together leading scientific groups from 5 European and 5 non-European countries who will study the molecular and biomechanical factors involved in the pathophysiology of connective tissues, including tendons, cartilage and bone. The ambitious obj ...
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 5

 TERMINÉ 

Restoring tissue regeneration in patients with visceral Graft versus Host Disease. (RETHRIM)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,

Stem cell regenerative therapies hold great promise for patients suffering from a variety of disorders that are associated with tissue or organ injury. Regeneration relies on tissue or organ-specific stem and progenitor cells, but can also aim at promoting the endogenous repair capacity of the body. Mesenchymal stromal cells (MSC) are undergoing clinical testing in a variety of clinical conditions ...
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 12

 TERMINÉ 

Combatting Bacterial Resistance in Europe (COMBACTE-NET)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2019,

The emergence of Antibiotic-resistant bacteria (ARB) is a global problem, having recently been elevated to the top three threats identified by the World Health Organisation (WHO), and subject of numerous national and international government activities, including the Trans-Atlantic Task Force on Antimicrobial Resistance established by the US and EU presidencies. The estimated costs of ARB are aro ...
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 38

 TERMINÉ 

European Prevention of Alzheimer’s Dementia Consortium (EPAD)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,

Background:The secondary prevention of Alzheimer’s dementia (AD) is achievable if we can identify individuals at risk of disease progression defined by biomarker evidence of AD pathology and no or only minimal clinical symptoms and engage them in a standing adaptive clinical trial, of the highest quality, testing multiple interventions. To achieve this, EPAD will also provide the analytical infras ...
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 40

 TERMINÉ 

Paediatric Inflammatory Bowel Diseases Network for Safety, Efficacy, Treatment and Quality improvement of care (PIBD-SETQuality)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

"The incidence of paediatric onset Inflammatory Bowel Diseases (PIBD) has risen dramatically in recent decades. Compared to adult forms, PIBD reflects a more severe disease, more often requiring aggressive treatment with immunomodulators, and thereby exposing children to a life-long risk of serious disease and treatment-related adverse events, such as infections and malignancies. Therefore, there ...
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 12

 TERMINÉ 

DC-based immunotherapy to treat Malignant Mesothelioma (H2020MM04)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

...sting of a combination of pemetrexed and cisplatin is considered standard of care with a median survival increase of 3 months (9-12 months).The department of pulmonary diseases of the Erasmus MC, Rotterdam, The Netherlands, in collaboration with international partners, have developed a promising personalised immunotherapy for MM with very limited adverse effects. The first clinical results show a ...
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 8

 TERMINÉ 

In Vivo Spectral Photon Counting CT Molecular Imaging in Cardio- and Neuro-Vascular Diseases (SPCCT)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

The objective of the SPCCT project is to develop and validate a widely accessible, new quantitative and analytical in vivo imaging technology combining Spectral Photon Counting CT and contrast agents, to accurately and early detect, characterize and monitor neurovascular and cardiovascular disease. Spectral Photon Counting Computed Tomography (SPCCT) is a new imaging modality, currently in develop ...
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 12

 TERMINÉ 

Image-Guided Surgery (IGS) and Personalised Postoperative Immunotherapy To Improving Cancer Outcome (ISPIC)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

The basic concept of our proposal is to develop nanoparticle-based encapsulated libraries of different immunotherapeutic biomolecules for treatment after surgery as part of a novel cancer management strategy. The current state-of-art for the management of cancer starts with surgery, after identification of an accessible tumour mass. Surgery remains an effective treatment option for many types of c ...
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 14