2 projets européens trouvés
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TERMINÉ
"Role of Liver Estrogen Receptor in female Energy Metabolism, Reproduction and Aging: What About Your Liver Sexual Functions?" (WAYS)
Date du début: 1 avr. 2013, Date de fin: 31 mars 2018,
"In mammals, the liver is the peripheral integrator of nutrient availability and energetic needs of the entire organism. We recently demonstrated that dietary amino acids (AA) activate liver Estrogen Receptors (ER) and that, in case of food scarcity, the lowered circulating AA decrease liver ER activity and reduce IGF-1 synthesis with the consequent blockage of the estrous cycle.Here, we hypothesi ...
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TERMINÉ
Imaging of Neuroinflammation in Neurodegenerative Diseases (INMiND)
Date du début: 1 mars 2012, Date de fin: 28 févr. 2017,
The goal of this proposal (INMiND) is to carry out collaborative research on molecular mechanisms that link neuroinflammation with neurodegeneration in order to identify novel biological targets for activated microglia, which may serve for both diagnostic and therapeutic purposes, and to translate this knowledge into the clinic. The general objectives of INMiND are:(i) to identify novel mechanisms ...
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