4 projets européens trouvés
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TERMINÉ
Mitochondrial calcium signalling: molecules, roles and pharmacological targeting (mitoCalcium)
Date du début: 1 avr. 2012, Date de fin: 31 mars 2017,
Mitochondrial Ca2+ homeostasis is an important component of the calcium-mediated cellular response to extracellular stimuli. It controls key organelle functions, such as aerobic metabolism and the induction of apoptotic cell death, and shapes the spatio-temporal pattern of the cytosolic [Ca2+] increase. While its physiological and pathological relevance is now fully appreciated, lack of molecular ...
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1
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TERMINÉ
Real neurons-nanoelectronics Architecture with Memristive Plasticity (RAMP)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2016,
Information processing in classical 'von Neumann' architectures is less efficient compared to biological counterparts when dealing with ill-posed problems and noisy data. The reason is that the biological brain is configured differently and the key is its evolving structure, where connectivity elements between individual neurons, the synapses, undergo 'birth' and 'death' as well as strengthening ...
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6
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TERMINÉ
Convergence Science Network of Biomimetics and NeuroTechnology (CSNII)
Date du début: 1 mars 2013, Date de fin: 29 févr. 2016,
Despite tremendous progress in neuroscience, ICT and related fields we are still unable to build perceptive, emotive and cognitive systems that are comparable with even simple insect brains with respect to function, energy sufficiency or computational power. One promising approach to answer this challenge is to translate principles underlying the abilities of natural systems into new technologies. ...
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6
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TERMINÉ
Physiological role of the peripheral benzodiazepine receptor and its implications in apoptotic cell-death signaling pathways (PBR AND APOPTOSIS)
Date du début: 3 mars 2008, Date de fin: 2 mars 2009,
The peripheral benzodiazepine receptor (PBR) is an 18-kDa protein receptor, mainly found on the outer mitochondrial membrane of cells. The PBR seems to play a role in several cellular functions, including heme synthesis, steroidogenesis, DNA synthesis, cell growth and differentiation.Recently, a role for PBR in apoptosis has also been proposed and a number of findings argue in favour of this:- ove ...
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