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14 projets européens trouvés

Recherche sur 125080 projets européens

 TERMINÉ 

The quantitative Bcl-2 interactome in apoptosis: decoding how cancer cells escape death (APOQUANT)

Date du début: 1 avr. 2013, Date de fin: 31 mars 2019,

The proteins of the Bcl-2 family function as key regulators of apoptosis by controlling the permeabilization of the mitochondrial outer membrane. They form an intricate, fine-tuned interaction network which is altered in cancer cells to avoid cell death. Currently, we do not understand how signaling within this network, which combines events in cytosol and membranes, is orchestrated to decide the ...
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 2

 TERMINÉ 

Synthetic Biology Approach to Adhesion-Mediated Environmental Sensing (SYNAD)

Date du début: 1 mai 2012, Date de fin: 30 avr. 2018,

The primary aims of this work are tightly connected: (i) development of a bio-inspired “synthetic cell” capable of self-assembling, self-propelling and environmental sensing prepared with reduced molecular complexity compared to living cells (ii) quantitative assessment of the bio-activity of specific cellular components within these “synthetic cells”, leading to better fundamental understanding o ...
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 2

 TERMINÉ 

Chiral Nanostructured Surfaces and Colloidal Microbots (CHIRALMICROBOTS)

Date du début: 1 févr. 2012, Date de fin: 31 janv. 2018,

"From scientific publications to the popular media, there have been numerous speculations about wirelessly controlled microrobots (microbots) navigating the human body. Microbots have the potential to revolutionize analytics, targeted drug delivery, and microsurgery, but until now there has not been any untethered microscopic system that could be properly moved let alone controlled in fluidic envi ...
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 1

 TERMINÉ 

Lab-in-a-tube and Nanorobotic biosensors (LT-NRBS)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

The goal of this project is to develop new types of biosensors based on two different approaches: (i) a new bioanalytic microsystem platform for cell growth, manipulation and analysis using on-chip integrated microtubes and (ii) the use of synthetic self-propelled nanomotors for bioanalytical and biosensing applications. Based on the novel “Lab-in-a-tube” concept, we will design a multifunctional ...
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 3

 TERMINÉ 

Smart Nanoplasmonics for Chemistry and Biology (SNCB)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,

"This multidisciplinary proposal will utilize smart plasmonic concepts to solve intriguing biological and chemical problems. The plasmonic nanostructures will be arranged using biochemical linkers to provide sharp multipolar resonances which are highly sensitive to structural changes in space. The resulting plasmon rulers enable high-resolution plasmon spectroscopy and render possible optical dete ...
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 1

 TERMINÉ 

Machine Learning for Personalized Medicine (MLPM2012)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

"Over the last decade, enormous progress has been made on recording the health state of an individual patient down to the molecular level of gene activity and genomic information – even sequencing a patient’s genome for less than 1000 dollars is no longer an unrealistic goal. However, the ultimate hope to use all this information for personalized medicine, that is to tailor medical treatment to th ...
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 11

 TERMINÉ 

Real neurons-nanoelectronics Architecture with Memristive Plasticity (RAMP)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2016,

Information processing in classical 'von Neumann' architectures is less efficient compared to biological counterparts when dealing with ill-posed problems and noisy data. The reason is that the biological brain is configured differently and the key is its evolving structure, where connectivity elements between individual neurons, the synapses, undergo 'birth' and 'death' as well as strengthening ...
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 6

 TERMINÉ 

Control for Green Energy-Efficient Technologies (COGENT)

Date du début: 1 déc. 2012, Date de fin: 30 nov. 2015,

The EU has set aggressive energy targets that will drive a significant increase in the use of renewable energy sources introducing large uncertainties in the power generation as well as the uptake of plug-in hybrid electric vehicles (PHEVs), offering a new source for balancing the power grid by providing large scale distributed storage capacity. The COGENT project will develop theoretical framewor ...
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 1

 TERMINÉ 

Complex Liquids At Structured Surfaces (CLASS)

Date du début: 1 mai 2011, Date de fin: 30 avr. 2015,

The topography and surface chemistry of substrates is now recognised to significantly impact on the feasibility and quality of many industrial processes where wetting and self-assembly phenomena play a major role. In the emerging lab-on-a-chip technologies based on integrated microfluidic devices, surface forces dominate, and inertial plays only a secondary role. Therefore, tailoring the solid-liq ...
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 3

 TERMINÉ 

Dynamics and Cooperative Phenomena in Complex Physical and Biological Media (DCP-PhysBio)

Date du début: 25 avr. 2011, Date de fin: 24 avr. 2015,

The goal of the DCP-PhysBio exchange program is to bring together several European teams (France, Germany, UK), Israel, as well as partners from Russia and Ukraine. We want to use our combined expertise to study various challenging dynamical and cooperative phenomena taking place in complex physical and biological systems. All the teams have a track record of research in these areas concentrating ...
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 6

 TERMINÉ 

Orthogonally Functionalized Binary Nanopatterned Polymeric Substrates for T cell activation and proliferation in Cancer Immunotherapy (OFB-SCI)

Date du début: 1 avr. 2013, Date de fin: 31 mars 2015,

"Harnessing the power of the immune system to fight malignancies remains a challenging goal although important progress has recently been achieved. For example, cancer remission of terminal leukemia patients was accomplished with genetically modified autologous T cells (Dr. June, University of Pennsylvania, 2011). However, these adoptive T cell therapies are limited by the availability of target s ...
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 1

 TERMINÉ 

Molecular Interfacial structure and dynamics of Nanoscopic droplets in Emulsions (MINE) (MINE)

Date du début: 1 nov. 2009, Date de fin: 31 oct. 2014,

Emulsions consist of one liquid dispersed as nanoscopic droplets in another liquid, such as milk, and butter. The understanding of the structure and stability of emulsions is commonly obtained from empirical studies in which a macroscopic parameter (like temperature or concentration of constituents) is varied. Since the work of Irving Langmuir and others (published in 1917) it is well established ...
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 3

 TERMINÉ 

Multifunctional Photothermal Gold Nanoarrays for Cellular Manipulation (Multi-PGNAs)

Date du début: 15 juil. 2008, Date de fin: 14 juil. 2010,

Transporting, organizing, attaching, guiding, releasing entities of various dimensions over different scales remain central to the development of high throughput biological devices able to conduct millions of tests in a short period of time. The proposed project intends to develop a new generation of substrates for cell manipulation based on photothermal processes. Specifically, it focuses on rea ...
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 2

 TERMINÉ 

Investigation of interfacial structure of buried inorganic-organic interfaces in organic photovoltaics -- LiF at organic-cathode interface (LiFOrganicPV)

Date du début: 1 juil. 2008, Date de fin: 30 juin 2010,

In order to improve the efficiency of organic microelectronic devices, there has to be a better understanding of both the connection between the crystalline structure and device performance, and the role that the organic/organic and inorganic/organic interfaces play in determining that structure. The main objective of the proposed research project is understanding the role of structure in solar ...
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 2