7 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Unrestricted Leveraging of Targets for Research Advancement and Drug Discovery (ULTRA-DD)
Date du début: 1 mars 2015, Date de fin: 29 févr. 2020,
ULTRA-DD (Unrestricted Leveraging of Targets for Research Advancement and Drug Discovery) will be an European-wide, highly collaborative and inclusive consortium, to validate new targets for drug discovery by (1) generating high quality research tools, with an emphasis on chemical probes; (2) generating the chemical probes in the most cost-effective manner, using structure-guided methods and harne ...
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10
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TERMINÉ
Analytical Research In ADME profiling (ARIADME) (ARIADME)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
The integration of absorption, distribution, metabolism and excretion (ADME) profiling into early drug discovery has been put forward as a strategy for reducing drug candidate attrition. Europe is challenged to develop novel ADME screening methodologies with increased efficiency and predictive power to profile the multitude of lead compounds currently being generated. The principal objective of th ...
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6
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TERMINÉ
Environmentally Low Impact Cooling Technology (ELICIT)
Date du début: 1 janv. 2014, Date de fin: 31 déc. 2016,
This proposal outlines a range of activities that will help efficient gas-free magnetic cooling move from being a laboratory scale technology to being a high-volume marketable product. This project specifically focuses on the application of magnetic cooling technology to the domestic refrigeration market. This is a technology being developed by SMEs but which will eventually be used by global app ...
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9
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TERMINÉ
STRATEGY TO INHIBIT TGF-Beta IN LIVER DISEASE (IT-LIVER)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,
Chronic liver diseases (CLD) and their end-stages, cirrhosis and hepatocellular carcinoma (HCC), are leading causes of morbidity and mortality worldwide with enormous socio-economic costs. Patients with liver cirrhosis are at high risk of deadly hepatic failure and over 80% of HCC develop on a cirrhotic background. HCC ranks as the 5th most common cancer and with >600,000 deaths per annum it const ...
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12
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TERMINÉ
The Open Pharmacological Concepts Triple Store (OPEN PHACTS)
Date du début: 1 mars 2011, Date de fin: 29 févr. 2016,
Drug discovery is data-hungry and all major pharmaceutical companies maintain extensive in-house instances of public data alongside internal. Analysis and hypothesis generation for drug-discovery projects requires assembly, overlay and comparison of data from many sources, requiring shared identifiers and common semantics. Expression profiles need to be overlaid with gene or pathway identifiers an ...
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32
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TERMINÉ
Electronic Health Record systems for Clinical Research (EHR4CR)
Date du début: 1 mars 2011, Date de fin: 29 févr. 2016,
Current medical needs, the growth of targeted therapies and personalized medicines, and escalating R&D costs result in formidable cost pressures on healthcare systems and the pharmaceutical industry. Clinical research is also growing in complexity, labour intensity and cost. There is a growing realization that the development and integration of Electronic Health Record systems (EHRs) for medical ...
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37
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TERMINÉ
Collaborative HIV and Anti-HIV Drug Resistance Network (CHAIN)
Date du début: 1 avr. 2009, Date de fin: 31 mars 2014,
CHAIN is a large scale integrating project aimed to effectively and durably combat new and existing anti-HIV drug resistance in clinical settings, with a special emphasis on Eastern Europe and in heavily affected resource-poor regions in Africa. This will be achieved through our pan-European network of surveillance and basic research activities, the involvement of all main actors in the field of H ...
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