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 TERMINÉ 

Hepatic and Cardiac Toxicity Systems modelling (HECATOS)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,

HeCaToS aims at developing integrative in silico tools for predicting human liver and heart toxicity. The objective is to develop an integrated modeling framework, by combining advances in computational chemistry and systems toxicology, for modelling toxic perturbations in liver and heart across multiple scales. This framework will include vertical integrations of representations from drug(metabol ...
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 14

 TERMINÉ 
Chlamydia trachomatis is a devastating human pathogen, causing blindness, infertility and systemic disease; related Chlamydia bacteria cause respiratory infections and pre-term abortions in other vertebrates. These bacteria all have an intricate intracellular lifecycle. Recent in depth genomic studies on Chlamydia trachomatis have provided insights into how this species uses recombination to incre ...
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 1

 TERMINÉ 
Genome sequencing initiated a new age in biology. Now, the emphasis is on the biological interpretation of the genome: zooming on the biological functioning of the gene-products, i.e. the proteins, emerging into a filed termed proteomics. Protein levels depend not only on mRNA levels, but also on translational controls & regulated degradation, making the measurement of expression at the protein le ...
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