3 projets européens trouvés
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TERMINÉ
Development of mouse mutant resources for functional analyses of human diseases - Enhancing the translation of research into innovation (INFRAFRONTIER-I3)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,
The mouse shows great similarities in development, physiology and biochemistry to humans, which makes it a key model for research into human disease. The major challenges for mouse functional genomics in the 21st century are to:• Develop a series of mutant alleles for every gene in the mouse genome• Determine the phenotypic consequences of each mutation• Identify mouse models for the complete dise ...
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24
Participants partenaires
TERMINÉ
Coordinating the cooperation of the ESFRI project Infrafrontier with the International Phenotyping Consortium (IMPC) (INFRACOMP)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2014,
InfraCoMP will establish efficient coordination mechanisms between the ESFRI project Infrafrontier and the International Mouse Phenotyping Consortium. Infrafrontier is a pan-European initative to build a sustainable research infrastructure for systemic phenotyping, archiving and distribution of mouse models of human diseases. The IMPC is a global project to carry out systemic phenotyping of mouse ...
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9
Participants partenaires
TERMINÉ
Infrafrontier The European infrastructure for phenotyping and archiving of model mammalian genomes (INFRAFRONTIER)
Date du début: 1 mars 2008, Date de fin: 31 déc. 2012,
Medically related Life Sciences use the mouse as a model system to understand the molecular basis of health and disease in humans (>95% similarity of genes in humans and mice). An essential task for Biomedical Sciences in the 21st century will be the functional analysis of mouse models for every gene in the mammalian genome. The major bottlenecks identified by the user community will be proper ...
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