3 projets européens trouvés
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TERMINÉ
Targeting novel lipid pathways for treatment of cardiovascular disease (Athero-Flux)
Date du début: 1 sept. 2013, Date de fin: 31 août 2018,
Lipid lowering has significantly reduced cardiovascular disease (CVD) mortality in EU. However, the aim to abolish CVD in EU is far from achieved and attempts to improve on the benefits of statins with new agents have not yet delivered new therapeutics. The Consortium Athero-Flux builds on FP7-generated large-scale lipidomics data showing that specific sphingolipids and in particular distinct cer ...
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12
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TERMINÉ
Targeting and exploiting B cell functions for treatment in cardiovascular disease (Athero-B-Cell)
Date du début: 1 sept. 2013, Date de fin: 31 août 2018,
Cardiovascular disease (CVD) mortality and morbidity is predicted to increase in Europe and worldwide in the next decades due to aging and the rise of diabetes and obesity. The link between metabolic and inflammatory disease is getting stronger, raising hopes for novel therapeutic targets to be exploited clinically. Clinical evidence generated by the Academic partners of the Athero-B-Cell Consorti ...
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11
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TERMINÉ
An urgent need exists for more specific treatment options to target the metabolic changes and the related inflammatory pathways during HF. Targeting microRNAs (miRNAs)-small RNAs implicated in protein regulation- represents a unique possibility to make novel medicines against HF. In view of the central role of inflammatory pathways in the metabolic syndrome, they expect inflammation miRNAs to be e ...
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