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Preclinical development of drugs and drug delivery technology for the treatment of inherited photoreceptor degeneration (DRUGSFORD)
Date du début: 1 sept. 2012, Date de fin: 31 août 2016,
Dysregulation of cGMP is a pathological hallmark of inherited retinal degenerations (RD) affecting photoreceptors, the sensory cells of the retina. These RDs, including Retinitis Pigmentosa, Lebers Congenital Amaurosis, and Achromatopsia, are major causes of blindness, affecting approximately one in every 2000 individuals worldwide, and remain without effective treatment. In photoreceptors, cGMP i ...
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