3 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Improving Prostate Cancer Outcome with Vectored Vaccines (IMPROVE)
Date du début: 1 avr. 2014, Date de fin: 31 mars 2018,
A successful vaccine against cancer is most likely to work through the induction of potent CD8+ T cells that can successfully kill tumour cells. But achieving this has proved difficult and only low level responses are induced by current vaccine approaches. Nonetheless, two therapeutic immunisation strategies have shown partial success in targeting prostate cancer, and one recently reached licensur ...
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5
Participants partenaires
TERMINÉ
Development of very promising humanized therapeutic mAbs efficiently neutralizing a novel immunosuppressive pathway involved in a wide range of cancers (TumAdoR)
Date du début: 1 sept. 2013, Date de fin: 31 août 2017,
Studies have demonstrated the importance of CD73 in the spread of cancer. Overexpressed in numerous cancer types, this enzyme leads to the production of high amounts of extracellular Adenosine, creating an immunosuppressive microenvironment, and contributing to tumor proliferation and dissemination. Neutralizing its activity represents a highly potent and innovative therapy.Following on the recent ...
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8
Participants partenaires
TERMINÉ
Hydroxitirosol, a new generation of microbicides targeting HIV through antiviral and anti-inflammatory pathways (AIM-HIV)
Date du début: 1 déc. 2012, Date de fin: 31 mai 2015,
Since the first cases of AIDS were reported 30 years ago, HIV remains a difficult target for the research field. Although there is no cure for AIDS, HIV infection can be prevented, however in many countries across the world access to prevention and treatment services is limited. Global leaders have pledged to work towards universal access to HIV prevention and care, so that millions of deaths can ...
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