6 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Integrating chemical approaches to treat pancreatic cancer: making new leads for a cure (Panacreas)
Date du début: 1 mars 2011, Date de fin: 29 févr. 2016,
Pancreatic ductal adenocarcinoma (PDAC) causes 34000 deaths in the EU every year. Conventional cancer treatments have close to no impact on this disease. As a result, almost all patients diagnosed with PDAC develop metastases and eventually die. Given this poor outlook, the search for new therapeutics is mandatory. These will have to target relevant cancer pathways and be designed based on the ava ...
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12
Participants partenaires
TERMINÉ
NANOTECHNOLOGICAL TOOLKITS FOR MULTI-MODAL DISEASE DIAGNOSTICS AND TREATMENT MONITORING (NAMDIATREAM)
Date du début: 1 juil. 2010, Date de fin: 30 juin 2014,
NAMDIATREAM will develop a cutting edge nanotechnology-based toolkit for multi-modal detection of biomarkers of most common cancer types and cancer metastases, permitting identification of cells indicative of early disease onset in a high-specificity and throughput format in clinical, laboratory and point-of-care devices. The project is built on the innovative concepts of super-sensitive and highl ...
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24
Participants partenaires
TERMINÉ
The Synthesis and Evaluation of Organometallic Dinuclear Ruthenium Complexes as Anti-Cancer Drugs (DINURU)
Date du début: 1 juil. 2011, Date de fin: 30 juin 2013,
"Current platinum-based anti-cancer drugs, such as cisplatin, are well established in the successful treatment of various forms of cancer, however, the use of these drugs is significantly limited by associated side effects and drug resistance. Ruthenium-based alternatives, some of which are in clinical testing, have shown considerable promise, exhibiting low general toxicity alongside selectivity ...
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1
Participant partenaire
TERMINÉ
Tandem catalysis for the production of biofuel related chemicals from biomass derived polyols (TCPBRCBDP)
Date du début: 1 mai 2010, Date de fin: 30 avr. 2012,
"One promising strategy for the production of biofuels from cellulosic, hemicellulosic and lipid materials is to use polyols as a platform. Recent advances have led to direct and (potentially) large scale production of polyols such as ethylene glycol, glycerol and sorbitol. Nevertheless, the downstream production of valuable fuels from polyols is comparatively lacking. In this project we intend to ...
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1
Participant partenaire
TERMINÉ
Sugar-linked Ruthenium-anticancer Complexes (SuRuCo)
Date du début: 1 mai 2008, Date de fin: 30 avr. 2010,
Cancer is a major cause of death in Europe, being second to heart disease and responsible more than 1.7 million (6.7 worldwide) lives every year. It is expected that these numbers will rise dramatically such that by 2020 more than 16 million new cases will be registered, with the number of deaths more than 10.3 million people per year worldwide (in Europe the number of deaths is estimated to rise ...
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1
Participant partenaire
TERMINÉ
Synthesis of Targeted Organometallic Anticancer Drugs and their mode of Action (STOADA)
Date du début: 1 mai 2009, Date de fin: 28 févr. 2010,
"The project is designed to study a new class of ruthenium antimetastasis compounds, which provides a flexible scaffold onto which various groups of known biological function can be grafted, in order to identify the mechanism of antimetastasis action and obtain superior compounds. In addition, targets will be identified from these compounds using an innovative bio-analytical method. The generic co ...
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