12 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Advanced Immunization Technologies (ADITEC)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2017,
Vaccines so far have been developed mostly by following an empiric approach. To prevent and possibly cure unresolved and emerging infectious diseases we need to fully exploit the potential of the human immune system. Progress in science and technology makes it possible to achieve what was previously deemed impossible. The scope of this project is to produce knowledge necessary to develop novel and ...
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53
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TERMINÉ
Global Research in Paediatrics (GRiP)
Date du début: 1 janv. 2011, Date de fin: 30 juin 2017,
Paediatric drugs (PD) lack appropriate testing. Most drugs have inadequate information about dosing regimen, dose adjustment and how to administer them. These are longstanding problems that unquestionably require concerted efforts at the international level. Both the US and the EU have introduced paediatric legislation that facilitates participation of children in research and pharmaceutical innov ...
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24
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TERMINÉ
Cutaneous and Mucosal HIV Vaccination (CUT'HIVAC)
Date du début: 1 janv. 2010, Date de fin: 31 déc. 2015,
Despite significant effort over the past decade to design and implement new vaccines strategies against HIV, no one has met its promise to prevent infection and/or to reduce viral load until reaching eradication of the HIV reservoir. To reach this goal, a translational research is critical to propose innovative approaches for an HIV vaccine enhancing broadly cross-reactive mucosal, humoral and cel ...
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18
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TERMINÉ
Combined Highly Active Anti-retroviral Microbicides (CHAARM)
Date du début: 1 janv. 2010, Date de fin: 30 juin 2015,
This proposal is for a large scale collaborative project in which we propose both to develop novel microbicides directed against new intracellular targets and to investigate novel combinations of highly active anti-retroviral drugs which may be particularly effective as microbicides. Combinations may enhance efficacy but equally importantly will increase the genetic barrier to the development of r ...
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34
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TERMINÉ
European multicenter network to evaluate pharmacokinetics, safety and efficacy of Meropenem in neonatal sepsis and meningitis (NEOMERO)
Date du début: 1 janv. 2010, Date de fin: 30 juin 2015,
Previous studies have demonstrated the high frequency of bacterial sepsis in neonates and infants admitted to neonatal intensive care unit (NICU), often associated with serious complications or death. Many pathogens capable of causing nosocomial bacterial sepsis in neonates and young infants have developed resistance to the antibiotics considered of choice for treatment. Meropenem is an antibiotic ...
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12
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TERMINÉ
Development of a Novel Treatment for Clostridium Difficile (DNTCD)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2013,
"We wish to exploit the need for effective treatment for nosocomial diarrhoea especially that caused by Clostridium difficiledisease (CDD). Patients treated with broad spectrum antibiotics are at greatest risk of CDD diarrhoea and many of thoseaffected are hospitalised elderly patients with serious underlying illnesses. Antibiotics can cause disruption of the normalintestinal flora, an important p ...
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9
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TERMINÉ
European Collaborative Project on Inflamation and Vascular Wall Remodelling in Atherosclerosis (ATHEROREMO)
Date du début: 1 mai 2008, Date de fin: 31 oct. 2013,
"The health of the EC population has never been better. However, serious public health problems remain, which cannot be ignored including high levels of premature death due to cardiovascular diseases. Thus, new preventive, diagnostic and therapeutic strategies against atherosclerotic cardiovascular diseases are needed. The atherosclerotic changes of the vascular wall are central in the developmen ...
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19
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TERMINÉ
Arrhythmogenic potential of drugs (ARITMO)
Date du début: 1 janv. 2010, Date de fin: 30 juin 2013,
The ability of some compounds to prolong the QT interval of the electrocardiogram and to precipitate Torsade de Pointes (TdP, a potentially fatal arrhythmia) has caused several regulatory interventions, including drug withdrawals. Specific guidelines have been implemented to detect QT liability of new compounds as early as possible. However there is growing evidence that an increase in the QT inte ...
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21
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TERMINÉ
Identification and development of vaccine candidates for Buruli Ulcer Disease (BuruliVac)
Date du début: 1 mars 2010, Date de fin: 31 mai 2013,
Buruli ulcer disease (BUD), caused by Mycobacterium ulcerans, is a neglected bacterial infection of the poor in remote rural areas, mostly affecting children. BUD, the third most common mycobacterial disease in immunocompetent humans after tuberculosis and leprosy, is most endemic in West Africa, but cases have been reported from more than 30 countries. BUD is a mutilating disease leading to sever ...
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16
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TERMINÉ
Access to Pharmaceuticals (ATP)
Date du début: 1 oct. 2009, Date de fin: 31 mars 2013,
Access to Pharmaceuticals Equitable access to pharmaceuticals, particularly for developing countries is an essential human right. Various complex impediments hinder access, which is the subject of ongoing multidisciplinary studies. Intellectual Property and product development are two issues that can be used as tools to address the problem of access, particularly to make patented drugs more afford ...
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5
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TERMINÉ
Contained Molecular Farming – Controllable Contained Systems for High Yield and Consistency (CoMoFarm)
Date du début: 1 juin 2009, Date de fin: 31 déc. 2012,
The CoMoFarm project will establish high-yielding production systems for pharmaceutical and industrial proteins based on plants, plant tissue and plant cells. The aim is to develop systems in which both the production host and the product itself show consistent yield and quality. The project will include a comparison of four alternative systems – hydroponic plants, root cultures, moss and suspensi ...
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10
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TERMINÉ
Multicentre discovery of breast cancer biomarkers (CANOMICS)
Date du début: 1 août 2010, Date de fin: 31 juil. 2012,
"Breast cancer is the most common cause of death from cancer among European women, and over half of the worldwide breast cancer related mortalities occur in the developing world. Despite improvements in surgical techniques and chemoradiotherapy, the ability to cure patients with breast cancer remains limited and five year survival for patients with advanced disease is dismal. Expression profiling ...
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