3 projets européens trouvés
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TERMINÉ
Outer Membrane Vesicles (OMVs) from “Vaccinobacter”: A Synthetic Biology approach for effective vaccines against infectious diseases and cancer (OMVAC)
Date du début: 1 juin 2014, Date de fin: 31 mai 2019,
This proposal intends to apply Synthetic Biology to create a new bacterial species, Vaccinobacter, devoted to the production of multivalent, highly effective vaccines. The project originates from the evidence that Outer membrane Vesicles (OMVs) naturally produced by all Gram-negative bacteria can induce remarkable protective immunity, a property already exploited to develop anti-Neisseria vaccines ...
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3
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TERMINÉ
Systems biology for the functional validation of genetic determinants of skeletal diseases (SYBIL)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,
"The aim of SYBIL is to carry out extensive functional validation of the genetic determinants of rare and common skeletal diseases and the age related factors contributing to these painful conditions. To achieve this goal SYBIL will gather complementary translational and transnational scientists, systems biologists, disease modellers, leading SMEs and industrialists that will perform in-depth char ...
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19
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TERMINÉ
Improving Prostate Cancer Outcome with Vectored Vaccines (IMPROVE)
Date du début: 1 avr. 2014, Date de fin: 31 mars 2018,
A successful vaccine against cancer is most likely to work through the induction of potent CD8+ T cells that can successfully kill tumour cells. But achieving this has proved difficult and only low level responses are induced by current vaccine approaches. Nonetheless, two therapeutic immunisation strategies have shown partial success in targeting prostate cancer, and one recently reached licensur ...
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