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THE ROLE OF O-GlcNAc IN BACTERIAL SIGNAL TRANSDUCTION AND VIRULENCE (SUGABACT)
Date du début: 1 nov. 2010, Date de fin: 31 oct. 2014,
O-GlcNAc modification of specific serines/threonines on intracellular proteins in higher eukaryotes has been shown to directly regulate important processes such as the cell cycle, insulin sensitivity and transcription. This dynamic modification, which shows interplay with protein phosphorylation, is regulated by two counteracting proteins, which catalyse transfer of GlcNAc from UDP-GlcNAc to speci ...
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